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Detection of Mycobacterium tuberculosis complex DNA in CD34-positive peripheral blood mononuclear cells of asymptomatic tuberculosis contacts : an observational study

Background: Haematopoietic stem cells expressing the CD34 surface marker have been posited as a niche for Mycobacterium tuberculosis complex bacilli during latent tuberculosis infection. Our aim was to determine whether M tuberculosis complex DNA is detectable in CD34-positive peripheral blood mononuclear cells (PBMCs) isolated from asymptomatic adults living in a setting with a high tuberculosis

The Irradiated brain microenvironment supports glioma stemness and survival via astrocyte-derived transglutaminase 2

The tumor microenvironment plays an essential role in supporting glioma stemness and radioresistance. Following radiotherapy, recurrent gliomas form in an irradiated microenvironment. Here we report that astrocytes, when pre-irradiated, increase stemness and survival of cocultured glioma cells. Tumor-naïve brains increased reactive astrocytes in response to radiation, and mice subjected to radiati

Poverty and new welfare economics

What is New Welfare Economics (NWE), how does it explain poverty, and what can we learn from this school of thought when it comes to poverty relief? Answering these questions is the aim in this chapter. The chapter opens with a description of the development of NWE and its central tools and concepts, providing a non-technical explanation of the differences between ʼnew’ and ‘old’ welfare economics.

HD 76920 b pinned down : A detailed analysis of the most eccentric planetary system around an evolved star

We present 63 new multi-site radial velocity (RV) measurements of the K1III giant HD 76920, which was recently reported to host the most eccentric planet known to orbit an evolved star. We focused our observational efforts on the time around the predicted periastron passage and achieved near-continuous phase coverage of the corresponding RV peak. By combining our RV measurements from four differen

Kelly trading and option pricing

In this paper we show that a Kelly trader is indifferent to trade a derivative if and only if the no-arbitrage price is uniquely given by the minimal martingale measure price, thus providing a natural selection mechanism for option pricing in incomplete markets. We also show that the unique Kelly indifference price results in market equilibrium in the sense that no Kelly trader can improve the mag

Djuren! Våra moraliska och nationella gränser

”Djuren! Våra moraliska och nationella gränser” (Gränsløs nr 11 2021) har fokus på hur människor, framförallt i Sverige och Danmark, kan förhålla sig till hästar, grisar och oxar, i både nutid och dåtid. Numret är redigerat av Johanna Rivano Eckerdal och Mia Krokstäde. Författarna i numret är verksamma inom filosofi, etologi, etnologi, medie- och kommunikationsvetenskap, sociologi, historia, arkeo

Patients' perspective on prostatic artery embolization : A qualitative study

Objectives: The aim was to describe the patients' experience of undergoing prostatic artery embolization.Methods: A retrospective qualitative interview study was undertaken with 15 patients of mean age 73 years who had undergone prostatic artery embolization with a median duration of 210 min at two medium sized hospitals in Sweden. The reasons for conducting prostatic artery embolization were clea

Persistent organic pollutants and the size of ovarian reserve in reproductive-aged women

Industrial chemicals such as persistent organic pollutants (POPs) have been associated with reduced fertility in women, including longer time-to-pregnancy (TTP), higher odds for infertility, and earlier reproductive senescence. Fertility is highly dependent on the ovarian reserve, which is composed of a prenatally determined stock of non-growing follicles. The quantity and quality of the follicles

Asynchronous δ13Ccarb and δ13Corg records during the onset of the Mulde (Silurian) positive carbon isotope excursion from the Altajme core, Gotland, Sweden

High-resolution paired analyses of δ13Ccarb and δ13Corg from a new drill core from Gotland, Sweden, demonstrate asynchronous positive change in the carbon isotope records during the onset of one of the major Silurian biogeochemical events known as the Mulde Event or “Big Crisis”. The detailed carbon isotope record presented here provides Δ13C (the difference between δ13Ccarb and δ13Corg) and allow

The two-loop perturbative correction to the (g − 2) μ HLbL at short distances

The short-distance behaviour of the hadronic light-by-light (HLbL) contribution to (g − 2)μ has recently been studied by means of an operator product expansion in a background electromagnetic field. The leading term in this expansion has been shown to be given by the massless quark loop, and the non-perturbative corrections are numerically very suppressed. Here, we calculate the perturbative QCD c

Catch-up dynamics in early industry lifecycle stages - A typology and comparative case studies in four clean-tech industries

The literature on catch-up cycles has not yet systematically conceptualized how catch-up dynamics differ between the various industries that are emerging in the green techno-economic paradigm. We address this gap by connecting catch-up cycle theory with an industry typology from global innovation systems (GISs) literature, which distinguishes four generic industry types with footloose, spatially s

Genome assembly, sex-biased gene expression and dosage compensation in the damselfly Ischnura elegans

The evolution of sex chromosomes, and patterns of sex-biased gene expression and dosage compensation, are poorly known among early winged insects such as odonates. We assembled and annotated the genome of Ischnura elegans (blue-tailed damselfly), which, like other odonates, has a male-hemigametic sex-determining system (X0 males, XX females). By identifying X-linked genes in I. elegans and their o

Influence of diabetes on diagnostic performance of computed tomography angiography of the calf arteries in acute limb ischemia

Background: Patients with diabetes mellitus (DM) have a more extensive distal arterial occlusive disease compared to non-diabetic patients. Diagnostic imaging is a necessity to identify the location and extent of the arterial occlusion in acute limb ischemia (ALI). Computed tomography angiography (CTA) is the most commonly used modality and the diagnostic performance with CTA of calf arteries may

Immune Profile in Patients With COVID-19 : Lymphocytes Exhaustion Markers in Relationship to Clinical Outcome

The velocity of the COVID-19 pandemic spread and the variable severity of the disease course has forced scientists to search for potential predictors of the disease outcome. We examined various immune parameters including the markers of immune cells exhaustion and activation in 21 patients with COVID-19 disease hospitalised in our hospital during the first wave of the COVID-19 pandemic in Slovakia

Agriculture for Development in the 21st Century : Evidence from Ethiopia

The 21st century has seen a rise of optimism about the prospects for African economic development, and Ethiopia, with its rapid economic growth in the last two decades, is at the forefront of this current wave of optimism. The rapid growth has been achieved under a policy focus on the agricultural sector – another aspect of development that has seen a renewed wave of optimism in the 21st century. The 21st century has seen a rise of optimism about the prospects for African economic development, and Ethiopia, with its rapideconomic growth in the last two decades, is at the forefront of this current wave of optimism. The rapid growth has been achievedunder a policy focus on the agricultural sector – another aspect of development that has seen a renewed wave of optimism in the21st century. Rec

Gaia Early Data Release 3: Summary of the contents and survey properties

Context. We present the early installment of the third Gaia data release, Gaia EDR3, consisting of astrometry and photometry for 1.8 billion sources brighter than magnitude 21, complemented with the list of radial velocities from Gaia DR2. Aims. A summary of the contents of Gaia EDR3 is presented, accompanied by a discussion on the differences with respect to Gaia DR2 and an overview of the main l