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Changes in regional fetal cerebral blood flow perfusion in relation to hemodynamic deterioration in severely growth-restricted fetuses

Objectives To study regional cerebral blood perfusion with power Doppler ultrasound (PDU) imaging in appropriate-for-gestational age (AGA) fetuses and those with intrauterine growth restriction (IUGR) at different hemodynamic stages of fetal deterioration. Methods Brain blood perfusion was studied with PDU imaging, and the fractional moving blood volume (FMB V) was estimated in 56 growth-restricte

Swedish guidelines on the management of community-acquired pneumonia in immunocompetent adults-Swedish Society of Infectious Diseases 2012

This document presents the 2012 evidence based guidelines of the Swedish Society of Infectious Diseases for the in-hospital management of adult immunocompetent patients with community-acquired pneumonia (CAP). The prognostic score 'CRB-65' is recommended for the initial assessment of all CAP patients, and should be regarded as an aid for decision-making concerning the level of care required, micro

Selecting analytical tools for characterization of polymersomes in aqueous solution

Selecting the appropriate analytical methods for characterizing the assembly and morphology of polymer-based vesicles, or polymersomes are required to reach their full potential in biotechnology. This work presents and compares 17 different techniques for their ability to adequately report size, lamellarity, elastic properties, bilayer surface charge, thickness and polarity of polybutadiene-polyet

Zebularine induces long-term survival of pancreatic islet allotransplants in streptozotocin treated diabetic rats.

Coping with the immune rejection of allotransplants or autologous cells in patients with an active sensitization towards their autoantigens and autoimmunity presently necessitates life-long immune suppressive therapy acting on the immune system as a whole, which makes the patients vulnerable to infections and increases their risk of developing cancer. New technologies to induce antigen selective l

On the shore

In 2006 a palisade enclosure dated to the late Middle Neolithic was excavated at Bunkeflostrand, Malmö, Sweden. The excavation of pits and wells containing flints, animal bones and pottery revealed a wide range of activities at the site, which is exceptional in comparison with most other palisade enclosures of southern Scandinavia. Palisade enclosures have emerged as places of great significance t

Multiple antibody reactivities to citrullinated antigens in sera from patients with rheumatoid arthritis: association with HLA-DRB1 alleles

Background: Autoantibodies to cyclic citrullinated peptides (anti-CCP) are present in most patients with rheumatoid arthritis ( RA), and associate with HLA-DRB1 shared epitope (SE) alleles. Objective: To investigate reactivities of anti-CCP to various citrullinated proteins/peptides, which represent potential autoantigens in RA, and to examine the relationship between such antibodies, and their as

Visual acuity and sensitivity increase allometrically with body size in butterflies

In insects, the surface area of the compound eye increases with body size both within and between species with only a slight negative allometry. This increase in surface area permits changes in eye structure that affect the eye's acuity and sensitivity, two features of eye performance that cannot be simultaneously maximized. Hence, as eye size varies within a lineage, so will the compromises betwe

Abort-on-Fail Test Scheduling for Modular SOCs without and with Preemption

System-on-chips (SOCs) and 3D stacked ICs are often tested for manufacturing defects in a modular fashion, enabling us to record the module test pass probability. We use this pass probability to exploit the abort-on-fail feature of automatic test equipment (ATE) and hence reduce the expected test time in the context of single-site testing. We present a model for calculation of expected test time,

Comment on "The mechanism for activation of GTP hydrolysis on the ribosome".

Voorhees et al. (Reports, 5 November 2010, p. 835) determined the structure of elongation factor Tu (EF-Tu) and aminoacyl-transfer RNA bound to the ribosome with a guanosine triphosphate (GTP) analog. However, their identification of histidine-84 of EF-Tu as deprotonating the catalytic water molecule is problematic in relation to their atomic structure; the terminal phosphate of GTP is more likely

Heavy-quark production in p plus p and energy loss and flow of heavy quarks in Au plus Au collisions at root s(NN)=200 GeV

Transverse momentum spectra of electrons (p(T)(e)) from semileptonic weak decays of heavy-flavor mesons in the range of 0.3 < p(T)(e) < 9.0 GeV/c have been measured at midrapidity (|y| < 0.35) by the PHENIX experiment at the Relativistic Heavy Ion Collider in p + p and Au + Au collisions at root s(NN) = 200 GeV. In addition, the azimuthal anisotropy parameter v(2) has been measured for 0.3 < p(T)(

The influence of large-amplitude librational motion on the hydrogen bond energy for alcohol-water complexes

The far-infrared absorption spectra have been recorded for hydrogen-bonded complexes of water with methanol and t-butanol embedded in cryogenic neon matrices at 2.8 K. The partial isotopic substitution of individual subunits enabled by a dual inlet deposition procedure provides for the first time unambiguous assignments of the intermolecular high-frequency out-of-plane and low-frequency in-plane d

Aspects of retransfusion of shed blood in cardiac surgery

Popular Abstract in Swedish De flesta större operationer på hjärtat idag kräver att hjärtat under en del av operationen står stilla utan att blod cirkulerar igenom det. För att kunna bibehålla ett blodflöde av syresatt blod genom kroppen kopplas en hjärt-lungmaskin till patienten. Blodet förs via slangar från höger förmak först ner till ett uppsamlingskärl, varifrån blodet pumpas vidare genom en oThe use of cardiotomy suction during open heart surgery with cardiopulmonary bypass (CPB) has a long tradition and often regarded as mandatory. Recently, studies have described potentially negative effects of cardiotomy suction with activation of the complement system, enhanced inflammatory response, hemolysis and coagulopathy. Emboli of various matters has also been studied. Whether they affect t

Two-stage anaerobic digestion of aerobic pre-treated sisal leaf decortications residues: hydrolases activities and biogas production profile

A two-stage system was investigated for anaerobic digestion (AD) of aerobically pre-treated sisal leaf decortication residue (SLDR) with regard to hydrolytic enzymes and biogas production. The system consisted of a solid-bed bioreactor for hydrolysis connected to methanogenic bioreactor packed with sisal fibre decortication residues (SFDR) as biofilm carriers. Some of the enzymes produced by micro

Effects of different boundary conditions on the long-range structure of polar liquids

The long-range order in strongly coupled dipolar systems has been studied using large-scale simulations for systems containing up to 100 000 particles. It is found that the boundary conditions used strongly influence the result. It is found that a periodic system modeled with the minimum image approximation yields an artificial order, whereas the same system described using the Ewald summation tec

Multimodal hard X-ray imaging of a mammography phantom at a compact synchrotron light source

The Compact Light Source is a miniature synchrotron producing X-rays at the interaction point of a counter-propagating laser pulse and electron bunch through the process of inverse Compton scattering. The small transverse size of the luminous region yields a highly coherent beam with an angular divergence of a few milliradians. The intrinsic monochromaticity and coherence of the produced X-rays ca

Re-evaluation of the fludrocortisone test: duration, NaCl supplementation and cut-off limits for aldosterone

Objective. Primary aldosteronism (PA) is the most common form of secondary hypertension. Thus, the aims of this study were: (1) to clarify whether the fludrocortisone suppression test (FST), which confirms autonomous aldosterone secretion, is reliable when carried out during a shorter period of time and (2) to confirm the importance of NaCl supplementation. The cut-off limits already obtained for