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The Role of Energy Quality in Shaping Long-Term Energy Intensity in Europe

On the European aggregate level there is an inverted-U curve for long-term energy intensity. In the 19th century aggregate European energy intensity rose, followed by a declining trend during the 20th century. This article discusses the possible explanations for the declining trend during the 20th century and explores the role of energy quality as expressed in energy prices. For the first time a c

Analysis of radon origin by backward atmospheric transport modelling

This work shows how ambient radon concentrations measured at Cabauw station in central Netherlands are influenced by transport from different regions under typical transport conditions occurring during April and November, 2007 by means of atmospheric Lagrangian particle dispersion modelling in a receptor-oriented approach. Four specific regions have been isolated to assess their contribution to th

Dystrophin deficiency reduces atherosclerotic plaque development in ApoE-null mice.

Dystrophin of the dystrophin-glycoprotein complex connects the actin cytoskeleton to basement membranes and loss of dystrophin results in Duchenne muscular dystrophy. We have previously shown injury-induced neointima formation of the carotid artery in mice with the mdx mutation (causing dystrophin deficiency) to be increased. To investigate the role of dystrophin in intimal recruitment of smooth m

Dynamic modelling of nitrous oxide emissions from three Swedish sludge liquor treatment systems.

The objective of this paper is to model the dynamics and validate the results of nitrous oxide (N2O) emissions from three Swedish nitrifying/denitrifying, nitritation and anammox systems treating real anaerobic digester sludge liquor. The Activated Sludge Model No. 1 is extended to describe N2O production by both heterotrophic and autotrophic denitrification. In addition, mass transfer equations a

Channel Estimation Algorithms for OFDM-IDMA: Complexity and Performance

Abstract in UndeterminedIn this paper, a number of channel estimation algorithms for iterative receivers are compared for the case of an up-link orthogonal frequency division multiplexing interleave division multiple access (OFDM-IDMA) system. Both pilot based algorithms, used to obtain an initial estimate, as well as semi-blind decision-directed algorithms working as a component of the iterative

Combined Costimulation Blockade Inhibits Accelerated Rejection Mediated by Alloantigen-primed Memory T Cells in Mice

Donor-reactive memory T cells threaten the survival of transplanted organs via multiple pathways. This study was undertaken to induce tolerance of cardiac allografts in mice, in which alloreactive memory T cells were adoptively transferred, by combined costimulatory blockade of both effector and memory T cells. We found that the median survival time (MST) of the grafts was 5.17 days in the untreat

Lactobacillus reuteri Maintains a Functional Mucosal Barrier during DSS Treatment Despite Mucus Layer Dysfunction

Treatment with the probiotic bacterium Lactobacillus reuteri has been shown to prevent dextran sodium sulfate (DSS)-induced colitis in rats. This is partly due to reduced P-selectin-dependent leukocyte-and platelet-endothelial cell interactions, however, the mechanism behind this protective effect is still unknown. In the present study a combination of culture dependent and molecular based T-RFLP

Introducing a gender-neutral pronoun in a natural gender language: the influence of time on attitudes and behavior

The implementation of gender fair language is often associated with negative reactions and hostile attacks on people who propose a change. This was also the case in Sweden in 2012 when a third gender-neutral pronoun hen was proposed as an addition to the already existing Swedish pronouns for she (hon) and he (han). The pronoun hen can be used both generically, when gender is unknown or irrelevant,

Adherence to a Mediterranean diet and risk of gastric adenocarcinoma within the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort study

Background: The Mediterranean dietary pattern is believed to protect against cancer, although evidence from cohort studies that have examined particular cancer sites is limited. Objective: We aimed to explore the association between adherence to a relative Mediterranean diet (rMED) and incident gastric adenocarcinoma (GC) within the European Prospective Investigation into Cancer and Nutrition stud

Presynaptic Mechanisms of l-DOPA-Induced Dyskinesia: The Findings, the Debate, and the Therapeutic Implications.

The dopamine (DA) precursor l-DOPA has been the most effective treatment for Parkinson's disease (PD) for over 40 years. However, the response to this treatment changes with disease progression, and most patients develop dyskinesias (abnormal involuntary movements) and motor fluctuations within a few years of l-DOPA therapy. There is wide consensus that these motor complications depend on both pre

Law, Norms, Piracy and Online Anonymity – Practices of de-identification in the global file sharing community

Purpose The purpose of this study is to better understand online anonymity in the global file-sharing community in the context of social norms and copyright law. The study describes the respondents in terms of use of Virtual Private Networks (VPNs) or similar services with respect to age, gender, geographical location, as well as analysing the correlation with file-sharing frequencies. Design/me

Anti-dyskinetic effect of anpirtoline in animal models of L-DOPA-induced dyskinesia

The serotonin system has emerged as a potential target for anti-dyskinetic therapy in Parkinson's disease. In fact, serotonin neurons can convert L-DOPA into dopamine, and mediate its synaptic release. However, they lack a feedback control mechanism able to regulate synaptic dopamine levels, which leads to un-physiological stimulation of post-synaptic striatal dopamine receptors. Accordingly, drug

Analyzing the Image Warp Forecast Verification Method on Precipitation Fields from the ICP

Image warping for spatial forecast verification is applied to the test cases employed by the Spatial Forecast Verification Intercomparison Project (ICP), which includes both real and contrived cases. A larger set of cases is also used to investigate aggregating results for summarizing forecast performance over a long record of forecasts. The technique handles the geometric and perturbed cases with

Oxidation of Fe(110) in oxygen gas at 400 degrees C

The initial oxidation of Fe(110) in oxygen gas at 400 degrees C beyond initial adsorbate structures has been studied using X-ray photoelectron spectroscopy, X-ray absorption spectroscopy, low-energy electron diffraction, and scanning tunneling microscopy (STM). Formation of several ordered phases of surface oxides is observed at oxygen coverages between approximately 2.3 and 3.5 oxygen atoms/Fe(11

Reducing the Cycle-Cycle Variability of a Natural Gas Engine Using Controlled Ignition Current

Running an internal combustion engine with diluted methane/air mixtures has a potential of reducing emissions and increasing efficiency. However, diluted mixtures need high ignition energy in a sufficiently large volume, which is difficult to accomplish. Increasing the spark duration has shown to be a promising way of delivering more energy into the diluted charge, but this requires a more sophist

Inverse Problems for Graph Laplacians

This thesis is devoted to inverse spectral problems for Laplace operators on metric graphs, and it is based on the following papers: Paper I - P. Kurasov and M. Nowaczyk 2005 Inverse spectral problem for quantum graphs J. Phys. A: Math. Gen 38 4901--15 Paper II - M. Nowaczyk 2007 Inverse spectral problem for quantum graphs with rationally dependent edges Operator Theory, Analysis and Mathematical

Endogenous IFN-β signaling exerts anti-inflammatory actions in experimentally induced focal cerebral ischemia.

Interferon (IFN)-β exerts anti-inflammatory effects, coupled to remarkable neurological improvements in multiple sclerosis, a neuroinflammatory condition of the central nervous system. Analogously, it has been hypothesized that IFN-β, by limiting inflammation, decreases neuronal death and promotes functional recovery after stroke. However, the core actions of endogenous IFN-β signaling in stroke a

Pattern of antigen expression in metastases after radioimmunotherapy of a syngeneic rat colon carcinoma utilizing the BR96 antibody.

Abstract ABSTRACT: BACKGROUND: Repeated administration of antibody-based therapies such as radioimmunotherapy depends on preserved antigen expression in tumor lesions. The purpose of this study was to evaluate whether the antigen expression in metastases observed after radioimmunotherapy differs from that of untreated primary tumors. FINDINGS: 30 of the 35 Brown Norway rats with syngeneic colon