Materials with heterogeneous microstructures architected across several scales are becoming increasingly popular in structural applications due to unique strength–ductility balance. One of the most popular 3D-architected structure designs is harmonic structure (HS) where soft coarse-grain (CG) islands are embedded in a hard continuous 3D skeleton of ultrafine grains (UFGs). In this work, a series

Since the Industrial Revolution, human activities have elevated atmospheric CO2 concentrations. The consequences of this include rising temperatures, shifts in precipitation patterns, and increased intensity and frequency of extreme weather events, such as heat waves and droughts. Elevated temperatures can accelerate microbial activity in soil, potentially resulting in an increased rate of soil or

OBJECTIVE:Recent advances in AI-based Large Language Models (LLM) can transform individuals’ descriptions of emotional health into numeric representations that predict rating scales with an accuracy approaching theoretical upper limits. This advancement enables examing various open-ended response formats. We develop and evaluate formats ranging from closed to more open: 1) selecting descriptive wo

Lipid metabolism dysregulation is a critical factor contributing to obesity. To counteract obesity-associated disorders, bariatric surgery is implemented as a very effective method. However, surgery such as Roux-en-Y gastric bypass (RYGB) is irreversible, resulting in life-long changes to the digestive tract. The aim of the present study was to elucidate changes in the fecal microbiota before and

Background: By being highly involved in the tumor evolution and disease progression of small cell lung cancer (SCLC), Myc family members (C-Myc, L-Myc, and N-Myc) might represent promising targetable molecules. Our aim was to investigate the expression pattern and prognostic relevance of these oncogenic proteins in an international cohort of surgically resected SCLC tumors. Methods: Clinicopatholo

Axially heterostructured nanowires (NWs) constitute a promising platform for advanced electronic and optoelectronic nanodevices. The presence of different materials in these NWs introduces a mismatch resulting in complex strain distributions susceptible of changing the band gap and carrier mobility. The growth of these NWs presents challenges related to the reservoir effect in the catalysts drople

Background: Quantitative cardiovascular magnetic resonance (CMR) first pass perfusion maps are conventionally acquired with 3 short-axis (SAX) views (basal, mid, and apical) in every heartbeat (3SAX/1RR). Thus, a significant part of the left ventricle (LV) myocardium, including the apex, is not covered. The aims of this study were 1) to investigate if perfusion maps acquired with 3 short-axis view

Language development is a long-term process. Individual-level longitudinal case studies have been foundational to SLA. However, methodologies that can support person-focused and process-oriented research lack consolidation. Qualitative longitudinal (QL) research (Neale, 2021a, 2021b) is a methodology that facilitates exploration of the influences of time over time. It provides a temporal architect

Den här boken handlar om de lexikogrammatiska förutsättningarnaför välfungerande och rimligt lättillgängliga inhemska lagtexter ochöversatta EU-rättsakter och -domar. Bokens huvudtes är attspråkformen i bägge fallen måste grundas på skriftlighet, dvs. på ettkvalificerat bruk av hela det formella skriftspråketskonstruktionsregister och med strikt tillämpning av dess generellanormsystem. Boken vände

Sustaining yields for smallholder perennial agriculture under a rapidly changing climate regime may require consideration of landscape features and on-farm management decisions in tandem. Optimising landscape and management may not be possible for maximising yields in any one year but maintaining heterogeneous landscapes could be an important climate adaptation strategy. In this study, we observed

The construction of large hydro infrastructures often causes severe socio-environmental issues. When the facility is projected on transboundary rivers, such as the Nile, these issues may become political and involve a much greater number of actors. The Grand Ethiopian Renaissance Dam (GERD) is provoking significant geopolitical tensions in the Horn of Africa since it involves two of the most dynam

Quality enhancement projects in universities frequently rely on short-term, fragmented studies implemented in response to snapshot data linked to student feedback. Such projects may not address the complex interplay across stakeholder groups and do not always acknowledge the unintended consequences of change. This article, focused on systems design, draws on research conducted over seventeen years

Despite decades of research on the pathophysiology of depression, the development of new therapeutic interventions has been slow, and no biomarkers of treatment response have been clinically implemented. Several lines of evidence suggest that the clinical and biological heterogeneity among patients with major depressive disorder (MDD) has hampered progress in this field. MDD with low-grade inflamm