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Cobalamin, folate, methylmalonic acid, homocysteine, and gastritis markers in dementia

The prevalence of dementia disorders, cobalamin and/or folate deficiency as well as gastritis increases with age. To investigate whether there is an association between these conditions, plasma homocysteine (Hcy), serum methylmalonic acid, serum cobalamin and blood folate concentrations were measured. Gastritis was indirectly diagnosed by measuring serum antibodies against H,K-ATPase, HELICOBACTER

Eta decays at and beyond p(4) in Chiral Perturbation Theory

An overview is given of Chiral Perturbation Theory and various applications to eta decays. In particular. the main decay eta --> 3pi is discussed at the one-loop level, and estimates of the higher order corrections are given. The importance of p(6) and higher order effects in double Dalitz and eta --> pi(0)gammagamma decays is pointed out. In all these cases the need for new experimental results i

Variability in diagnosis of clue cells, lactobacillary grading and white blood cells in vaginal wet smears with conventional bright light and phase contrast microscopy

Objective: Study the reproducibility of wet smear interpretation of clue cells, lactobacillary grades and leukocyte dominance with conventional bright light and phase contrast microscopy. Study design: Sets of vaginal specimens were taken from unselected consecutive women attending an outpatient gynaecology clinic. Air-dried vaginal fluid on a microscope slide was rehydrated with isotonic saline b

Equilibrium sampling through membrane based on a single hollow fibre for determination of drug-protein binding and free drug concentration in plasma

The determination of drug-protein binding and free drug concentration in plasma applying the equilibrium sampling through membrane (ESTM) technique has been studied using supported liquid membrane extraction in a single hollow fibre without any membrane carrier. In the extraction setup, the donor phase (plasma or buffer) was placed in the vial, into which was immersed the hollow fibre with the acc

Systematics of the Dactylorhiza euxina/incarnata/maculata polyploid complex (Orchidaceae) in Turkey: evidence from allozyme data

Material of Dactylorhiza were sampled from 49 localities in Turkey and investigated for allozyme variation at ten loci (nine enzyme systems). Among diploids, the Anatolian D. osmanica and D. umbrosa were allozymically variable, but not distinct from each other or from D. incarnata. Dactylorhiza saccifera contained the same alleles as the European D. fuchsii. Dactylorhiza iberica and D. euxina were

Landscape analysis of the Huang He headwaters, NE Tibetan Plateau - Patterns of glacial and fluvial erosion

The large-scale geomorphology of the Huang He (Yellow River) headwaters, centered around the Bayan Har Shan (5267 m asl) in the northeastern part of the Tibetan Plateau, is dominated by an uplifted remnant of a low-refief relict plateau with several mountain ranges. We have performed geomorphological mapping using SRTM topographic data and Landsat 7 ETM+ satellite imagery to evaluate landscape cha

Electrical "wiring" of viable Gluconobacter oxydans cells with a flexible osmium-redox polyelectrolyte

An application of a flexible polyvinylimidazole osmium functionalised polymer for efficient electrical wiring of whole Gluconobacter oxydans cells is described. The performance of the redox polymer as a mediator for intact bacterial cells was tested with glucose, ethanol and glycerol, typical substrates of the periplasmically localised PQQ-dependent membrane bound dehydrogenases. The efficiency of

Extracellular matrix in disc degeneration.

The extracellular matrix of the intervertebral disc structures contains many molecules also found in cartilage. The extremely polyanionic proteoglycans play a central role, particularly in the nucleus, by creating an osmotic environment leading to retention of water and ensuing resistance to deformation—important for the resilience of the tissue. Another major structural entity particularly impor

Subcutaneous alemtuzumab vs ATG in adjusted conditioning for allogeneic transplantation: influence of Campath dose on lymphoid recovery, mixed chimerism and survival.

Sixty-nine consecutive patients ( median age 54 years) were prospectively enrolled in a single-institution protocol for allogeneic transplantation with adjusted non-myeloablative fludarabine - melfalan-based conditioning including cyclosporin A and MMF, and one of three modes of serotherapy. Thirty-one donors (45%) were unrelated. The first cohort of 29 had ATG (Thymoglobulin 2 mg/kg x 3 days), th

Absence of the common IGF1 19 CA-repeat allele is more common among BRCA1 mutation carriers than among non-carriers from BRCA1 families.

BRCA1 mutations predispose to early-onset breast cancer. We previously reported an association between absence of the common IGF1 19 CA-repeat allele (IGF1-19/-19) and being a BRCA1 mutation carrier in young women from breast cancer high-risk families. Others have reported a four-fold risk of premenopausal breast cancer in women with a family history and the IGF1-19/-19 genotype. The aim of this s

Stratospheric ozone, ultraviolet radiation, and cryptogams

The stratospheric ozone layer, which protects the biosphere from biologically active (mostly harmful) ultraviolet-B (UV-B) solar radiation, thinned during the latter half of the 20th century. In this paper some of the effects of UV-B radiation on cryptogams (cyanobacteria, algae, lichens, mosses, liverworts, pteridophytes and fungi) are reviewed. Effects vary among species, and therefore changes i

Low genetic diversity among isolates of the nematode-trapping fungus Duddingtonia flagrans: evidence for recent worldwide dispersion from a single common ancestor

The genetic variation of Duddingtonia flagrans, which has become a promising biocontrol agent of animal parasitic nematodes, was investigated in a worldwide collection of 22 isolates. We analysed the sequence variation in four nuclear genes, tubA (beta-tubulin), CMD1 (calmodulin), EF1alpha (translation elongation factor 1alpha), and PII (extracellular serine protease). 1428 aligned base pairs (bp)

Which depth dose data should be used for dose planning when wedge filters are used to modify the photon beam?

The use of beam data for open photon fields when calculating absorbed dose distributions for beams with wedge filters has been studied. The depth doses for beams with wedge filters are changed through beam hardening and the dose maximum can be shifted; both these changes result in errors in the final dose calculations of several per cent if open beam data are used. The errors are larger for 6 MV t

Hepatitis C virus genotypes in different regions of the former Soviet Union (Russia, Belarus, Moldova, and Uzbekistan)

The prevalence of HCV genotypes in four republics of the former Soviet Union (Russia, Belarus, Moldova, and Uzbekistan) was investigated. Overall, 197 HCV isolates from 66 blood donors and 131 patients with chronic hepatitis were typed. Viral sequences from sera of infected subjects were amplified by nested RT-PCR using primers from the core region and typed by one or two techniques: (1) DNA enzym

The experiences of treatment from other people as narrated by people with moderate or severe traumatic brain injury and their close relatives

Purpose. The aim of this study was to describe the treatment from other people as experienced by people with moderate or severe traumatic brain injury (TBI) and their close relatives. Method. Twelve people with moderate or severe TBI and eight of their close relatives were interviewed. The interviews were analysed using thematic content analysis. Results. The results were described by the means of

An everyday struggle- Swedish families' lived experiences during a child's cancer treatment

The aim was to elucidate families' lived experience during a child's cancer treatment. Interviews were conducted with members of 11 affected families. A hermeneutical phenomenological approach was chosen. "Focus on the ill child-An everyday struggle" emerged as an essential theme. The families' lived experience of daily life was described as "feeling drained," "disrupting family life," "feeling lo