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Positive effect of removal of subchondral bone plate for cemented acetabular component fixation in total hip arthroplasty: a randomised RSA study with ten-year follow-up.

We hypothesised that the removal of the subchondral bone plate (SCBP) for cemented acetabular component fixation in total hip arthroplasty (THA) offers advantages over retention by improving the cement-bone interface, without jeopardising implant stability. We have previously published two-year follow-up data of a randomised controlled trial (RCT), in which 50 patients with primary osteoarthritis

Structured illumination for 3-D Mie imaging and 2-D attenuation measurements in optically dense sprays

Qualitative description of spray structure and geometry in the near-field region of atomizing sprays is particularly challenging due to the lack of visibility through such optically dense media. Similarly, quantitative determination of the optical depth can be particularly underestimated as a result of detecting photons which have experienced a number of scattering events. In this paper we demonst

Old Puzzle, New Insights: A Lithium-rich Giant Quietly Burning Helium in Its Core

About 1% of giant stars have been shown to have large surface Li abundances, which is unexpected according to standard stellar evolution models. Several scenarios for lithium production have been proposed, but it is still unclear why these Li-rich giants exist. A missing piece in this puzzle is the knowledge of the exact stage of evolution of these stars. Using low-and-high-resolution spectroscopi

A combined crystal plasticity and graph-based vertex model of dynamic recrystallization at large deformations

A mesoscale model of microstructure evolution is formulated in the present work by combining a crystal plasticity model with a graph-based vertex algorithm. This provides a versatile formulation capable of capturing finite-strain deformations, development of texture and microstructure evolution through recrystallization. The crystal plasticity model is employed in a finite element setting and allo

Search for supersymmetry in pp collisions at root s=7 Te V in final states with missing transverse momentum and b-jets with the ATLAS detector

The results of a search for supersymmetry in events with large missing transverse momentum and heavy-flavor jets using an integrated luminosity corresponding to 2.05 fb(-1) of pp collisions at root s = 7 TeV recorded with the ATLAS detector at the Large Hadron Collider are reported. No significant excess is observed with respect to the prediction for standard model processes. Results are interpret

How expensive is Big Science? Consequences of using simple publication counts in performance assessment of large scientific facilities

Although the nuclear era and the Cold War superpower competition have long since passed, governments are still investing in Big Science, although these large facilities are nowadays mostly geared towards areas of use closer to utility. Investments in Big Science are also motivated not only by promises of scientific breakthroughs but also by expectations (and demands) of measurable impact, and with

Exact evaluation of the depletion force between nanospheres in a polydisperse polymer fluid under Θ conditions.

We analyze a system consisting of two spherical particles immersed in a polydispersed polymer solution under theta conditions. An exact theory is developed to describe the potential of mean force between the spheres for the case where the polymer molecular weight dispersity is described by the Schulz-Flory distribution. Exact results can be derived for the protein regime, where the sphere radius (

Searches for heavy long-lived charged particles with the ATLAS detector in proton-proton collisions at root s=8 TeV

Searches for heavy long-lived charged particles are performed using a data sample of 19.1 fb(-1) from proton-proton collisions at a centre-of-mass energy of root s = 8 TeV collected by the ATLAS detector at the Large Hadron Collider. No excess is observed above the estimated background and limits are placed on the mass of long-lived particles in various supersymmetric models. Long-lived tau slepto

2-year follow-up report on micromotion of a short tibia stem.

Background and purpose - A shortened tibial stem could influence the early prosthetic fixation. We therefore compared the short stem to the standard-length stem using radiostereometric analysis (RSA) as primary outcome measure. Patients and methods - 60 patients were randomized to receive a cemented Triathlon total knee arthroplasty (TKA) with a tibial tray of either standard or short stem length.

A CFAR Adaptive Subspace Detector Based on a Single Observation in System-Dependent Clutter Background

In this paper, the problem of detecting target in system-dependent clutter (SDC) background with a single observation from the test cell is researched. Classical detectors, such as the generalized likelihood ratio detectors (GLRDs) and the adaptive matched filters (AMFs), etc., usually deal with the clutter and the noise as a whole. The low rank detectors (LRDs) make use of the low rank property o

The Struggle for History: Lindsay Anderson Teaches Free Cinema

In spring 1986, Lindsay Anderson appeared in a television programme on British cinema. This was part of a series of three under the heading British Cinema: Personal View, produced by Thames Television. Anderson’s contribution, Free Cinema 1956–? An Essay on Film by Lindsay Anderson, was written and directed by him. He was also the star of the programme, providing a lecture on the history of Britis

Conformational dynamics and thermodynamics of protein-ligand binding studied by NMR relaxation.

Protein conformational dynamics can be critical for ligand binding in two ways that relate to kinetics and thermodynamics respectively. First, conformational transitions between different substates can control access to the binding site (kinetics). Secondly, differences between free and ligand-bound states in their conformational fluctuations contribute to the entropy of ligand binding (thermodyna

M1 Protein-Dependent Intracellular Trafficking Promotes Persistence and Replication of Streptococcus pyogenes in Macrophages

Streptococcus pyogenes is an important human pathogen that causes a variety of diseases including life-threatening invasive diseases, such as toxic shock and deep tissue infections. Although S. pyogenes are classically considered extracellular pathogens, a clinical significance of an intracellular source has been emphasized. In patients with deep tissue infections, an intracellular reservoir of S.

The Psychosocial Atmosphere in Community-Based Activity Centers for People with Psychiatric Disabilities: Visitor and Staff Perceptions.

This study investigated how visitors and staff in community-based activity centers in Sweden perceived the psychosocial atmosphere and whether this could be explained by the centers' orientation (work-oriented versus meeting place-oriented centers). Eighty-eight visitors and 37 staff members at three work-oriented and three meeting place-oriented centers participated. The Community-oriented Progra

Ovarian Cancer and Body Size: Individual Participant Meta-Analysis Including 25,157 Women with Ovarian Cancer from 47 Epidemiological Studies

Background: Only about half the studies that have collected information on the relevance of women's height and body mass index to their risk of developing ovarian cancer have published their results, and findings are inconsistent. Here, we bring together the worldwide evidence, published and unpublished, and describe these relationships. Methods and Findings: Individual data on 25,157 women with o