Low molecular weight heparins (LMWH's) are used to prevent and treat thrombosis. Tests for monitoring LMWH's include anti-factor Xa (anti-FXa), activated partial thromboplastin time (aPTT) and thrombin generation. Anti-FXa is the current gold standard despite LMWH's varying affinities for FXa and thrombin.

Popular Abstract in Swedish Denna avhandling syftar till att föreslå, utvärdera och applicera testprocedurer för rationalitet, svag separabilitet och effektivitet. Främst behandlas icke-parametriska så kallade ’revealed preference’ procedurer, vilka har fördelen att de, till skillnad från den parametriska ansatsen, inte behöver anslå någon funktionell form för nyttofunktionen. En majoritet av de tThis thesis aims to propose, evaluate and apply test procedures for rationality, weak separability and efficiency. In particular, it focuses on nonparametric revealed preference procedures. This approach has the advantage of not having to stipulate any functional form for the utility function, unlike the parametric approach which relies on finding a suitable functional form for the utility functio

Sophisticated statistical analyses are common in ecological research, particularly in species distribution modeling. The effects of sometimes arbitrary decisions during the modeling procedure on the final outcome are difficult to assess, and to date are largely unexplored. We conducted an analysis quantifying the contribution of uncertainty in each step during the model-building sequence to variat

The herbaceous understory forms the richest stratum in temperate broadleaved forests in terms of plant diversity. Understanding the process of understory succession is thus of critical importance for the development of management guidelines for biodiversity restoration in post-agricultural plantation forests. We studied effects of stand age, forest fragmentation, and soil and canopy conditions on

Background: A delay in surgical nerve repair results in impaired nerve function in humans, but mechanisms behind the weakened nerve regeneration are not known. Activating transcription factor 3 (ATF3) increases the intrinsic growth state of injured neurons early after injury, but the role of long-term changes and their relation to axonal outgrowth after a delayed nerve repair are not well understo

Reklamen blinkar, ljuder, ändrar färg och form. Söta djur och maskotar svischar förbi, tonas ned, dyker plötsligt upp igen. Köp, beställ, registrera dig, klicka här! Ibland skriker den högljutt. Ibland är den helt tyst, knappt synlig, svår att fånga, svår att skilja ut, men uppmuntrar till interaktion och pockar på barns uppmärksamhet. Marknadsförare är allt mer angelägna om att kommunicera med ba

The most typical enhancement for electrokinetic remediation (EKR) involves the neutralization of the alkaline front generated at the cathode by the addition of an acid to the catholyte. Although the use of strong and weak acids can be found in the literature, there is still a clear lack of reliable comparisons between them. This paper presents a comparison of the results obtained for a real lead c

The objective of this exploratory study was to develop signal processing methods for assisting in the diagnosis of arteriovenous fistula stenosis on patients suffering from end-stage renal disease and undergoing haemodialysis treatments. The proposed method is based on the classification of vessels sounds utilizing parameter extraction from wavelets transform coefficients. The coefficients energy

Popular Abstract in Swedish Joniserande strålning används ofta som behandling vid olika tumörsjukdomar i bukhåla och bäckenregion men är ibland förenad med biverkningar. Dessa kan uppkomma tidigt/akut, dvs i direkt anslutning till genomförd behandling eller sent, efter månaderår. Besvären kan vara av mycket varierande och ofta lindrig övergående karaktär såsom buksmärtor, diarré och blödningar fråGastrointestinal tract damage is an insidious feature in patients undergoing radiotherapy. Microvascular inflammation, including leukocyte and platelet recruitment as well as epithelial barrier dysfunction, are considered to constitute key components in the pathophysiology of radiation-induced enteropathy. The aim of this thesis was to investigate the basic mechanisms behind leukocyte-platelet-end

The glial cell line-derived neurotrophic factor (GDNF) has an important role in neuronal survival through binding to the GFRα1 (GDNF family receptor alpha-1) receptor and activation of the receptor tyrosine kinase Ret. Transient brain ischemia alters the expression of the GDNF signaling machinery but whether the GDNF receptor proteins are also affected, and the functional consequences, have not be

Popular Abstract in Swedish Made in China - På hur många av dina barns leksaker står det? Produktionen inom många sektorer flyttas från Europa till länder där arbetskraften är billigare. Forskningen i avhandlingen "Modeling and Control of Stiff Robots for Flexible Manufacturing" ska hjälpa europeiska småföretag att bli mer konkurrenskraftiga och samtidigt underlätta för arbetarna. Högt ljud frånTo survive on a global market, small and medium size enterprises (SMEs) require affordable and competitive industrial automation for high quality flexible manufacturing. This thesis contributes to the development of robot concepts that fit the needs of SMEs. A major part of the thesis deals with the modeling of the three degree-of-freedom (DOF) Gantry-Tau parallel kinematic robot, which has the po

Background: Despite conflicting results after surgically treated ankle fractures few studies have evaluated the effects of different types of training programs performed after plaster removal. The aim of this study was to evaluate the effects of a 12-week standardised but individually suited training program ( training group) versus usual care ( control group) after plaster removal in adults with

This study aimed to assess the costs and benefits of three alternative second-line treatment strategies for Swedish patients with type 2 diabetes mellitus (T2DM) who fail to reach glycated hemoglobin (HbA1c) ≤ 7% with metformin treatment alone: glucagon-like peptide-1 (GLP-1) receptor agonists, dipeptidyl peptidase-4 (DPP-4) inhibitors, and neutral protamine Hagedorn (NPH) insulin.

The aim of this myocardial perfusion imaging (MPI) study was to compare the diagnostic performance of two computer-aided diagnosis (CAD) systems, EXINI Heart(TM) (EXINI), and PERFEXTM (PERFEX) Emory Cardiac Toolbox (ECT), and the summed stress score (SSS) values from both software packages. We studied 1,052 consecutive patients who underwent 2-day stress/rest Tc-99m-sestamibi MPI studies. The refe

There is growing evidence of the importance of extramatrical mycelium (EMM) of mycorrhizal fungi in carbon (C) cycling in ecosystems. However, our understanding has until recently been mainly based on laboratory experiments, and knowledge of such basic parameters as variations in mycelial production, standing biomass and turnover as well as the regulatory mechanisms behind such variations in fores

Cultivated fields and forests in South China are experiencing serious damage due to invasive alien plants. We investigated the relation between DNA C-values and invasiveness. The DNA C-values of 23 species ranged from 0.39 pg to 3.37 pg. Herbs, perennials and native species had higher mean DNA C-values than shrubs, annuals and invasive alien species. DNA C-values decreased with increasing invasive

Background: A beneficial role of fish consumption on the risk of myocardial infarction (MI) has been reported and is mostly ascribed to n-3 (omega-3) fatty acids. However, fish also contains methylmercury, which may increase the risk of MI. Objective: The objective was to determine how fish consumption and erythrocyte concentrations of mercury (Ery-Hg) and selenium (Ery-Se) are related to the risk