Chaperones protect other proteins against misfolding and aggregation, a key requirement for maintaining biological function. Experimental observations of changes in solubility of amyloid proteins in the presence of certain chaperones are discussed here in terms of thermodynamic driving forces. We outline how chaperones can enhance amyloid solubility through the formation of heteromolecular aggrega

Genetic diversity is the basis for evolutionary adaptation and selection under changing environmental conditions. Phytoplankton populations are genotypically diverse, can become genetically differentiated within small spatiotemporal scales and many species form resting stages. Resting stage accumulations in sediments (seed banks) are expected to serve as reservoirs for genetic information, but so

More than 20 years after the adoption of UN Security Council Resolution 1325 on Women, Peace and Security, the international community is concerned with taking stock of its implementation in countries undergoing transitions from war to peace. This article contributes to a better understanding of the dynamics involved in implementing the Women, Peace and Security agenda through a focus on the frict

The eddy-covariance (EC) method is the most direct micrometeorological approach to measure the surface–atmosphere trace gases under turbulent conditions. The measurement of trace gas fluxes by eddy covariance requires fast-response instruments (higher than 1 Hz) to measure the turbulent fluctuations of vertical wind velocity and trace gas mixing ratio. For many trace gas species, such fast respons

Background: The use of firefighting foams at a military airport resulted in high levels of perfluorinated substances (PFAS) in the drinking water distributed to one-third of households in the Swedish municipality of Ronneby between the mid-1980s and the end of 2013. Method: The Ronneby Register Cohort, a large cohort comprising all individuals (N = 60,507) who ever lived in the Ronneby municipalit

Background: Evaluation of cardiac resynchronization therapy (CRT) often includes New York Heart Association (NYHA) classification, and echocardiography. However, these measures have limitations. Perfusion gradients from ventilation/perfusion single-photon emission computed tomography (V/P SPECT) are related to left-heart filling pressures and have been validated against invasive right-heart cathet

Purpose: Prostate cancer is the second most common cancer in men and a leading cause of cancer mortality worldwide. Men with drug use disorders (DUD) may potentially be at high risk for prostate cancer mortality because of delayed diagnosis and/or undertreatment. In this study, we aimed to investigate prostate cancer incidence, mortality, and stage at time of diagnosis among men with DUD compared

SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase (dNTPase) that restricts viral replication in infected cells and limits the sensitivity to cytarabine by hydrolysing its active metabolite, as recently shown in acute myeloid leukemia. Cytarabine is an essential component in the Nordic mantle cell lymphoma protocols (MCL2 and MCL3) for induction and high-dose chemotherapy treatment befor

This thesis is a study of Twelver Shi’a Islam in the context of Azeri-Turkish Muslims living in the Anatolia-Caucasus borderlands of Northeastern Turkey. Taking the sonic as the central focus and field of enquiry I listen to the ways that sound mediates between bodies, both somatic and social, and the divine in the ritual and quotidian lives of Shi’i practitioners. I argue that sound, voice and li

This study explores the control degree in success criteria operationalization. A literature review reveals that control degree relates to two patterns operationalizing success criteria: one directed to measurement and measure selection; the other directed to operationalization through the conceptualization of a relationship between a specific factor and project success. While in both patterns tighThis study explores the control degree in success criteria operationalization. A literature review reveals that control degree relates to two patterns operationalizing success criteria: one directed to measurement and measure selection; the other directed to operationalization through the conceptualization of a relationship between a specific factor and project success. While in both patterns tigh