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Multicomponent services for symptoms in serious respiratory illness : a systematic review and meta-analysis

Background People living with serious respiratory illness experience a high burden of symptoms. This review aimed to determine whether multicomponent services reduce symptoms in people with serious illness related to respiratory disease. Methods Electronic databases were searched to identify randomised controlled trials (RCTs) evaluating multicomponent services that enrolled patients due to sympto

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Around one in ten Central Asians work abroad. Most migrant workers are Uzbeks, followed by Tajiks and Kyrgyz. They leave their homeland because of poverty and a lack of prospects. Many go to Russia. Their remittances from there to their home country are an important economic factor. In Russia, migrants live under difficult conditions. Many end up living illegally. So-called “digital neighbourhoods

Stimuli-responsive drug delivery systems for inflammatory skin conditions

Inflammatory skin conditions highly influence the quality of life of the patients suffering from these disorders. Symptoms include red, itchy and painful skin lesions, which are visible to the rest of the world, causing stigmatization and a significantly lower mental health of the patients. Treatment options are often unsatisfactory, as they suffer from either low patient adherence or the risk of

The EUropeanisation of Research Infrastructure Policy

Political interest in Research Infrastructures on a European scale has been a new phenomenon, marked in the early 2000s with the launch of the Lisbon Strategy and the European Research Area. European Research Infrastructure policy then developed through, first, the strategic incorporation of incumbents through new modes of coordination; second, the European Commission’s emphasis of joint responsib

The genus Siderus (Lepidoptera: Lycaenidae) in French Guiana : four newly discovered species and conspicuous male genitalia polymorphism

The species of Siderus Kaye present in French Guiana are listed and detailed with notes on male territorial behavior and the plants at which adults feed. In total, seven species were recorded: Siderus leucophaeus (Hübner); Siderus parvinotus Kaye (first record from French Guiana); Siderus athymbra (Hewitson); Siderus diringeri Faynel, Robbins & Fåhraeus sp. nov.; Siderus bisignatus Faynel, Ram

Hypoxia-induced complement component 3 promotes aggressive tumor growth in the glioblastoma microenvironment

Glioblastoma (GBM) is the most aggressive form of glioma with a high rate of relapse despite intensive treatment. Tumor recurrence is tightly linked to radio-resistance, which in turn is associated with hypoxia. Here, we discovered a strong link between hypoxia and local complement signaling using publicly available bulk, single-cell, and spatially resolved transcriptomic data from patients with G

Opioids for the palliation of symptoms in people with serious respiratory illness : a systematic review and meta-analysis

Background People living with serious respiratory illness experience a high burden of distressing symptoms. Although opioids are prescribed for symptom management, they generate adverse events, and their benefits are unclear. Methods We examined the efficacy and safety of opioids for symptom management in people with serious respiratory illness. Embase, MEDLINE and the Cochrane Central Register of

A test of strangeness quantum number conservation in proton-proton collisions

The study delves into the production of (multi-) strange hadrons in proton-proton collisions at LHC. Novel observables are proposed to distinguish between Epos4, based on core-corona separation between a thermalised QGP phase and a vacuum phase with global strangeness conservation, and Pythia 8.3, based on microscopic interactions between Lund strings that conserve strangeness locally. Correlation

Maternal Accommodation of Adolescent Body Dysmorphic Disorder : Clinical Correlates and Association with Treatment Outcomes

Family accommodation (FA) is widely-recognised as an important clinical phenomenon in obsessive–compulsive disorder (OCD) and anxiety disorders, and is related to poorer treatment outcomes. However, FA has not been quantitatively explored in Body Dysmorphic Disorder (BDD). The aim of this study was to investigate the patterns and correlates of maternal accommodation in adolescent BDD, and its asso

No Effects of Auditory and Visual White Noise on Oculomotor Control in Children with ADHD

Background: White noise stimulation has demonstrated efficacy in enhancing working memory in children with ADHD. However, its impact on other executive functions commonly affected by ADHD, such as inhibitory control, remains largely unexplored. This research aims to explore the effects of two types of white noise stimulation on oculomotor inhibitory control in children with ADHD. Method: Memory gu

Re-Os geochronology and geochemical evolution of late Cambrian to Middle Ordovician Alum and Tøyen shales, Sweden

The limited number of accurate and precise radiometric ages through the ~100 Myr span of the Cambrian and Ordovician impedes reliable age determinations for stage boundaries in these periods. Here, we fill significant gaps in the early Paleozoic chronostratigraphy by providing precise Re-Os time-pins. Sample selection is linked to a firm biostratigraphic framework built on the appearance and distr

The Ordovician of Scandinavia: a revised regional stage classification

The Ordovician of Scandinavia (i.e. Denmark, Norway and Sweden) has been investigated for over two centuries and, through time, various chronostratigraphic schemes have been introduced, facilitating regional correlation. However, a modern chronostratigraphy has never been proposed. Here, we delineate ten regional stages for the Ordovician of Scandinavia, comprising, in ascending order, the Slemmes

Perceived global accent in Turkish heritage speakers in Germany : The impact of exposure and use for early bilinguals

This chapter is concerned with Turkish heritage speakers (HSs) in Germany, here exemplified by 21 early bilinguals during adulthood who live in Hamburg, North Germany. We introduce the population, report their self-perceived proficiency and propose the Turkish Use Score (TUS) that is based on quantitative aspects of language use (e.g., the number of people Turkish is spoken with) and qualitative o

Formal Linguistics and Language Education : Bridging the Gap

In this chapter, we provide a brief introduction to recent work in linguistics that has its origin and motivation in formal linguistics and theoretical acquisition research, and on this basis indicates potential connections and contributions to language pedagogy, including students’ and teachers’ beliefs about what ‘grammar’ actually is.