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Increased postnatal concentrations of pro-inflammatory cytokines are associated with reduced IGF-I levels and retinopathy of prematurity

Objective: Retinopathy of prematurity (ROP) is a multifactorial disease linked to low insulin-like growth factor (IGF)-I levels and perhaps to postnatal inflammation. Here, we investigated the longitudinal postnatal serum concentrations of pro-inflammatory cytokines interleukin (IL)-6 and tumor necrosis factor (TNF)-α in relation to IGF-I levels and ROP. Design: The study cohort included 52 infant

Does Female Leadership Matter? An Analysis of Swedish Foreign Ministers and their Parliamentary Speeches, 1955–2016

The current Swedish Foreign Minister, Margot Wallström, has in her foreign policy statement claimed that a feminist foreign policy will be an integral part of activities throughout the Swedish Foreign Service. Even though an explicit ‘feminist foreign policy’ is a rather recent and ‘Swedish’ phenomenon, foreign policies in line with such a general ‘feminist’ agenda may have been implemented throug

SNPs related to vitamin D and breast cancer risk : A case-control study

Background: It has been suggested that vitamin D might protect from breast cancer, although studies on levels of vitamin D in association with breast cancer have been inconsistent. Genome-wide association studies (GWASs) have identified several single-nucleotide polymorphisms (SNPs) to be associated with vitamin D. The aim of this study was to investigate such vitamin D-SNP associations in relatio

Sustained Psoriasis Area and Severity Index, Dermatology Life Quality Index and EuroQol-5D response of biological treatment in psoriasis : 10 years of real-world data in the Swedish National Psoriasis Register

Background: Few studies have analysed the long-term effects of biological treatment in psoriasis. PsoReg, the Swedish national register for systemic psoriasis treatment, started in 2006 and now includes 10 years of real-world data on the effectiveness of biological treatment. Objectives: To analyse the long-term real-world outcome data of patients who are biologically naïve with moderate-to-severe

Phototransduction in fan worm radiolar eyes

Fan worms (Annelida: Sabellidae) are sessile polychaetes that spend their adult lives in tubes and project their fans, composed of radiolar tentacles, up into the water column for respiration and filter feeding. To protect the fan from predation, many species have evolved unique compound eyes on the radioles that function as shadow or motion detectors, eliciting a rapid withdrawal response in reac

Emotion regulation individual therapy for adolescents with nonsuicidal self-injury disorder : A feasibility study

Background: Nonsuicidal self-injury (NSSI) is a serious health risk behavior that forms the basis of a tentative diagnosis in DSM-5, NSSI Disorder (NSSID). To date, established treatments specific to NSSI or NSSID are scarce. As a first step in evaluating the feasibility, acceptability, and utility of a novel treatment for adolescents with NSSID, we conducted an open trial of emotion regulation in

Assessing the GeneRead SNP panel for analysis of low-template and PCR-inhibitory samples

Massive parallel sequencing (MPS) is increasingly used for human identification purposes in forensic DNA laboratories. Forensic DNA samples are by nature heterogeneous and of varying quality, both concerning DNA integrity and matrices, creating a need for assays that can handle low amounts of DNA as well as impurities. Commercial short tandem repeat (STR) analysis kits for capillary electrophoresi

Altered structural network organization in cognitively normal individuals with amyloid pathology

Recent findings show that structural network topology is disrupted in Alzheimer's disease (AD), with changes occurring already at the prodromal disease stages. Amyloid accumulation, a hallmark of AD, begins several decades before symptom onset, and its effects on brain connectivity at the earliest disease stages are not fully known. We studied global and local network changes in a large cohort of

Causal nature of neighborhood deprivation on individual risk of coronary heart disease or ischemic stroke : A prospective national Swedish co-relative control study in men and women

We studied the association between neighborhood socioeconomic status (SES) and incidence of coronary heart disease (CHD) or ischemic stroke in the total population and in full- and half-siblings to determine whether these associations are causal or a result from familial confounding. Data were retrieved from nationwide Swedish registers containing individual clinical data linked to neighborhood of

Design of DISCO—Direct or Subacute Coronary Angiography in Out-of-Hospital Cardiac Arrest study

Background Acute coronary syndrome is a common cause of out-of-hospital cardiac arrest (OHCA). In patients with OHCA presenting with ST elevation, immediate coronary angiography and potential percutaneous coronary intervention (PCI) after return of spontaneous circulation are recommended. However, the evidence for this invasive strategy in patients without ST elevation is limited. Observational st

Efficacy and safety of outpatient treatment with direct oral anticoagulation in pulmonary embolism

Anticoagulant treatment of acute pulmonary embolism (PE) has traditionally been hospital-based. The lesser need for monitoring with the increasingly used direct acting oral anticoagulants (DOAC) in comparison to warfarin potentially facilitates outpatient treatment of PE with these drugs. This study aimed to evaluate efficacy and safety of outpatient treatment of PE with DOAC. We extracted data fr

Current smoking is associated with a larger waist circumference and a more androgenic profile in young healthy women from high-risk breast cancer families

The purpose was to elucidate the interplay between current smoking, anthropometric measurements, and endogenous hormone levels in women ≤ 40 years. Questionnaires on lifestyle and reproductive factors were completed by 269 healthy women from high-risk breast cancer families between 1996 and 2006 in Sweden. Blood samples for analyses of plasma testosterone, estradiol, androstenedione, sex hormone-b

Introduction : “Formulas of Betrayal”—Traitors, Collaborators and Deserters in Contemporary European Politics of Memory

Basing their study on conceptualizations current in anthropology, history, memory studies, and cultural sociology, Eleonora Narvselius and Gelinada Grinchenko offer a new, complex approach to understanding the violations of loyalty and trust that constitute betrayal, as well as their present-day revisions. Acts of betrayal and their subsequent reinterpretations are viewed through the prism of powe

Femtoscopy with identified charged pions in proton-lead collisions at s NN =5.02 TeV with ATLAS

Bose-Einstein correlations between identified charged pions are measured for p+Pb collisions at sNN=5.02TeV using data recorded by the ATLAS detector at the CERN Large Hadron Collider corresponding to a total integrated luminosity of 28nb-1. Pions are identified using ionization energy loss measured in the pixel detector. Two-particle correlation functions and the extracted source radii are presen