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Kardiovaskulär sjukdom och diabetes typ II som riskfaktorer för kognitiv sjukdom

En kort sammanställning i tidningen Neurolog i Sverige av våra två artiklar som presenterar prevalensen av kardiovaskulär sjukdom och typ 2 diabetes i olika kognitiva sjukdomar. Här visar vi att Alzheimer's sjukdom och Lewykroppssjukdom, de två vanligaste neurodegenerativa sjukdomarna, har en signifikant lägre förekomst av både kardiovaskulär sjukdom och typ 2 diabetes jämfört med vaskulär demens.Here we presented a review of our two articles presenting the prevalence of cardiovascular disease and diabetes in neurocognitive disorders; Alzheimer's disease, vascular dementia, mixed dementa and Lewy body disease. Cardiovascular disease and diabetes showed a significantly lower prevalence among cases with Alzheimer's disease and Lewy body disease, both neurodegenerative disorders, compared to

The Logic behind Quine's Criterion of Ontological Commitment

This article first explains why Quine took first‐order classical logic to be the only language in which we should formulate a theory or declarative statement to determine its ontological commitments. I then argue that Quineans cannot relax Quine's restriction to classical logic such that any nonclassical logic may be used to uncover a theory's ontological commitments. The reason is that this leads

High density supercritical carbon dioxide for the extraction of pesticide residues in onion with multivariate response surface methodology

The excessive use of pesticides is a serious health problem due to their toxicity and bioaccumulation through the food chain. Due to the complexity of foods, the analysis of pesticides is challenging often giving large matrix effects and co‐extracted compounds. To overcome this problem, a selective and “green” supercritical fluid extraction method was developed, using neat carbon dioxide as a solv

Muscle mass and plasma myostatin after exercise training : a substudy of Renal Exercise (RENEXC)-a randomized controlled trial

BACKGROUND: Sarcopenia increases as renal function declines and is associated with higher morbidity and mortality. Myostatin is a negative regulator of muscle growth. Its expression in response to exercise is unclear. In this prespecified substudy of the Renal Exercise (RENEXC) trial, we investigated the effects of 12 months of exercise training on sarcopenia, muscle mass and plasma myostatin and

Prime-boost vaccination strategy enhances immunogenicity compared to single pneumococcal conjugate vaccination in patients receiving conventional DMARDs, to some extent in abatacept but not in rituximab-treated patients

OBJECTIVE: To explore whether a prime-boost vaccination strategy, i.e., a dose of pneumococcal conjugate vaccine (PCV) and a dose of 23-valent polysaccharide vaccine (PPV23), enhances antibody response compared to single PCV dose in patients with inflammatory rheumatic diseases treated with different immunosuppressive drugs and controls. METHODS: Patients receiving rituximab (n = 30), abatacept (n

Different domains of self-reported physical activity and risk of type 2 diabetes in a population-based Swedish cohort : the Malmö diet and Cancer study

BACKGROUND: While a dose-response relationship between physical activity and risk of diabetes has been demonstrated, few studies have assessed the relative importance of different measures of physical activity on diabetes risk. The aim was to examine the association between different self-reported measures of physical activity and risk of type 2 diabetes in a prospective cohort study. METHODS: Out

Non-radiative decay and fragmentation in water molecules after 1a1-14a1 excitation and core ionization studied by electron-energy-resolved electron-ion coincidence spectroscopy

In this paper, we examine decay and fragmentation of core-excited and core-ionized water molecules combining quantum chemical calculations and electron-energy-resolved electron-ion coincidence spectroscopy. The experimental technique allows us to connect electronic decay from core-excited states, electronic transitions between ionic states, and dissociation of the molecular ion. To this end, we ca

Biomolecular analyses reveal the age, sex and species identity of a near-intact Pleistocene bird carcass

Ancient remains found in permafrost represent a rare opportunity to study past ecosystems. Here, we present an exceptionally well-preserved ancient bird carcass found in the Siberian permafrost, along with a radiocarbon date and a reconstruction of its complete mitochondrial genome. The carcass was radiocarbon dated to approximately 44-49 ka BP, and was genetically identified as a female horned la

Augustinus många kvinnor : Bibliska och historiska kvinnor i Augustinus skrifter om jungfrulighet och äktenskap

The following article discusses the role different women play in shaping Augus-tine’s theological thoughts on marriage and virginity. It argues that Augustine developed different definitions of Christian marriage, holy virginity and conse-cratedwidowhood through ongoing contacts with contemporary women such as Proba, Juliana and Demetrias. Furthermore, biblical women as, for example, Ruth, the pro

European Position Paper on Rhinosinusitis and Nasal Polyps 2020

The European Position Paper on Rhinosinusitis and Nasal Polyps 2020 is the update of similar evidence based position papers published in 2005 and 2007 and 2012. The core objective of the EPOS2020 guideline is to provide revised, up-to-date and clear evidence-based recommendations and integrated care pathways in ARS and CRS. EPOS2020 provides an update on the literature published and studies undert

Towards a European health research and innovation cloud (HRIC)

The European Union (EU) initiative on the Digital Transformation of Health and Care (Digicare) aims to provide the conditions necessary for building a secure, flexible, and decentralized digital health infrastructure. Creating a European Health Research and Innovation Cloud (HRIC) within this environment should enable data sharing and analysis for health research across the EU, in compliance with

Routing using Safe Reinforcement Learning

The ever increasing number of connected devices has lead to a metoric rise in the amount data to be processed. This has caused computation to be moved to the edge of the cloud increasing the importance of efficiency in the whole of cloud. The use of this fog computing for time-critical control applications is on the rise and requires robust guarantees on transmission times of the packets in the ne

Double quantum-dot engine fueled by entanglement between electron spins

The laws of thermodynamics allow work extraction from a single heat bath provided that the entropy decrease of the bath is compensated for by another part of the system. We propose a thermodynamic quantum engine that exploits this principle and consists of two electrons on a double quantum dot (QD). The engine is fueled by providing it with singlet spin states, where the electron spins on differen

Adaptive Routing with Guaranteed Delay Bounds using Safe Reinforcement Learning

Time-critical networks require strict delay bounds on the transmission time of packets from source to destination. Routes for transmissions are usually statically determined, using knowledge about worst-case transmission times between nodes. This is generally a conservative method, that guarantees transmission times but does not provide any optimization for the typical case. In real networks, the