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Increasing number of long-lived ancestors associates with up to a decade of healthspan extension and a healthy metabolomic profile in mid-life
Globally, the lifespan of populations increases but the healthspan is lagging behind. Previous research showed that survival into extreme ages (longevity) clusters in families as illustrated by the increasing lifespan of study participants with each additional long-lived family member. Here we investigate whether the healthspan in such families follows a similar quantitative pattern using three-ge
European Prurigo Project: Underlying aetiology and comorbidities in patients with chronic nodular prurigo.
Realism - en intern angelägenhet?
Det verkar vara naturligt för oss människor att i metafysisk mening ha realistiska uppfattningar om världen. Våra vardagliga intuitioner säger oss att ting som exempelvis stolar och bord existerar, och att de gör det oberoende av oss och vad vi tänker, tror och tycker om det. Vi verkar också ha en intuitiv förståelse av sanning som någon form av korrespondens mellan ord och värld. Ett påstående so
4s-4p transitions including intercombination lines in Zn-like Zr XI, Nb XII and Mo XIII
Energy levels of the configurations 4s4p and 4p2 in zink-like Zr, Nb and Mo have been derived through the identification of spectral lines emitted from laser-produced plasmas. Intercombination lines in the 4s4p-4p2 transition connect the singlet and triplet systems. Wavelengths for spinforbidden and magnetic quadrupole ground term combinations have been derived from the energy levels.
Dendrokronologisk analys av enskärret 1:244 på Ingarö, Värmdö kommun
Dendrokronologisk analys av en bod på Slattefors 4:15, "Stora Lund", i Lunds by, Linköpings kommun
Dendrokronologisk analys av stugan på Norbergsby 12:78 i Norberg, Västermanland
The Hydration State of Bone Tissue Affects Contrast in Neutron Tomographic Images
Neutron tomography has emerged as a promising imaging technique for specific applications in bone research. Neutrons have a strong interaction with hydrogen, which is abundant in biological tissues, and they can penetrate through dense materials such as metallic implants. However, in addition to long imaging times, two factors have led to challenges in running in situ mechanical characterization e
Measurements of the groomed and ungroomed jet angularities in pp collisions at √s = 5.02 TeV
The jet angularities are a class of jet substructure observables which characterize the angular and momentum distribution of particles within jets. These observables are sensitive to momentum scales ranging from perturbative hard scatterings to nonperturbative fragmentation into final-state hadrons. We report measurements of several groomed and ungroomed jet angularities in pp collisions at s = 5.
Muon reconstruction and identification efficiency in ATLAS using the full Run 2 pp collision data set at √s=13 TeV
This article documents the muon reconstruction and identification efficiency obtained by the ATLAS experiment for 139 fb - 1 of pp collision data at s=13 TeV collected between 2015 and 2018 during Run 2 of the LHC. The increased instantaneous luminosity delivered by the LHC over this period required a reoptimisation of the criteria for the identification of prompt muons. Improved and newly develop
Historiografi och naturalism i ljuset av antropocen
Jordens inträde i antropocen har lett till att historievetenskapens traditionella motsättningar mellan natur och kultur, samt den mänskliga historiens tid och geologisk tid har börjat ifrågasättas. Hur står sig historievetenskapens traditionella syften och metoder i förhållande till den pågående omförhandlingen mellan historiografi och naturalism?
Real-world wintertime CO, N2O, and CO2 emissions of a central European village
Although small rural settlements are only minor individual sources of greenhouse gases and air pollution, their high overall occurrence can significantly contribute to the total emissions of a region or country. Emissions from a rural lifestyle may be remarkably different than those of urban and industrialized regions, but nevertheless they have hardly been studied so far. Here, flux measurements
Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation
We assembled an ancestrally diverse collection of genome-wide association studies (GWAS) of type 2 diabetes (T2D) in 180,834 affected individuals and 1,159,055 controls (48.9% non-European descent) through the Diabetes Meta-Analysis of Trans-Ethnic association studies (DIAMANTE) Consortium. Multi-ancestry GWAS meta-analysis identified 237 loci attaining stringent genome-wide significance (P < 5 ×
Unequal excess mortality during the Spanish Flu pandemic in the Netherlands
A century after the Spanish Flu, the COVID-19 pandemic has brought renewed attention to socioeconomic and occupational differences in mortality in the earlier pandemic. The magnitude of these differences and the pathways between occupation and increased mortality remain unclear, however. In this paper, we explore the relation between occupational characteristics and excess mortality among men duri
Birthweight, BMI in adulthood and latent autoimmune diabetes in adults : a Mendelian randomisation study
Aims/hypothesis: Observational studies have found an increased risk of latent autoimmune diabetes in adults (LADA) associated with low birthweight and adult overweight/obese status. We aimed to investigate whether these associations are causal, using a two-sample Mendelian randomisation (MR) design. In addition, we compared results for LADA and type 2 diabetes. Methods: We identified 43 SNPs actin
Improving human papillomavirus (HPV) testing in the cervical cancer elimination era : The 2021 HPV LabNet international proficiency study
Background: Proficient Human Papillomavirus (HPV) genotyping services are essential to support HPV and cervical cancer elimination strategies, in particular to support HPV vaccine research. Objectives: To perform a global HPV genotyping proficiency study, with evaluation in relation to previous proficiency studies. Study design: The proficiency panel contained 44 coded samples (40 samples containi
Detailed luminescence dating of dust mass accumulation rates over the last two glacial-interglacial cycles from the Irig loess-palaeosol sequence, Carpathian Basin
Mineral dust records distant from dust sources are crucial in establishing wider atmospheric dust loads in the past. However, detailed, independent chronologies for loess-palaeosol sequences distant from local dust sources are still rare in Europe. In this study we present a high-resolution OSL and pIRIR290 chronology and multi-proxy investigation of the Irig loess-palaeosol sequence (LPS), Vojvod
Enhancing Environmental Protection in Relation to Armed Conflict: An Assessment of the ILC Draft Principles
This article examines the outcome of the International Law Commission’s (ILC) Study on the Protection of the Environment in relation to Armed Conflict as adopted on first reading. The twenty-eight draft principles, adopted by the ILC in July 2019, aim to enhance environmental protection before, during, and after armed conflict. This article evaluates the strengths and weaknesses of the draft princ
Resolving or intensifying crisis? Examining public perceptions of crisis public diplomacy in foreign and domestic contexts
This paper focuses on public diplomacy efforts during crises that involve multiple, transboundary, and often hostile publics. Traditionally, public diplomacy is employed to resolve crises (Zaharna, 2004) and bring about understanding from foreign publics (Pamment, 2012). Recently, some studies point to a new style of public diplomacy that intentionally causes and intensifies crises for the purpose