The paper proposes a new multiple window method for estimating a peaked spectrum. The multiple windows are adapted to the signal, giving a less biased estimate for estimation of peaks than does the Thomson multiple window method. Still the result from estimation of a flat spectrum shows comparable results in variance reduction. The method is based on solution of an eigenvalue problem where the eig

The latency and amplitude of the midlatency auditive evoked potential's (AEP) Nb-trough has been found to indicate the depth of anaesthesis. The aim of this paper is to present a system that reliably estimates these parameters without a long time delay. The result shows that it is possible to estimate and track changes in latency and amplitude of the Nb-trough with a delay below 1 minute at a stim

Hur man beskriver och eftersträvar välbefinnande är viktigt, eftersom det påverkar både forskning och samhället i stort. Denna avhandling handlar om hur välbefinnande definieras och mäts, vilket både innefattar en kritisk diskussion kring befintliga teorier om välbefinnande samt en utveckling av empiriska metoder och statistiska verktyg för att öka vår förståelse gällande hur personer uppfattar ocHow to define and measure individuals’ well-being is important, as this has an impact on both research and society at large. This thesis concerns how to define and measure the self-reported well-being of individuals, which involves both theorizing as well as developing and applying empirical and statistical methods in order to gain a better understanding of well-being.The first paper critically re

Background: Steroid nasal irrigation for chronic rhinosinusitis patients following endoscopic sinus surgery reduces symptom recurrence. There are minimal safety data to recommend this treatment. This study evaluated the safety of betamethasone nasal irrigation by measuring its impact on endogenous cortisol levels. Methods: Participants performed daily betamethasone nasal irrigation for six weeks.

Den 14 januari började det nya året enligt den rysk-ortodoxa julianska kalendern. Vad kan man då anta att år 2013 kommer innebära för Ryssland och ryssarna? Spekulerande är en vansklig syssla, men jag ska ändå försöka skissa ett tänkbart scenario. Texten nedan är alltså en personlig reflektion över de tendenser man kan se i Ryssland just nu, och vad dessa skulle kunna innebära för utvecklingen und

During the last decade, the serotonergic system has emerged as a key player in the appearance of L-DOPA-induced dyskinesia in animal models of Parkinson’s disease. Clinical investigations, based on imaging and postmortem analyses, suggest that the serotonin neurons are also involved in the etiology of this complication of long-term L-DOPA treatment in parkinsonian patients. These findings have sti

Minimalinvasiv mitralisklaffkirurgi är en komplex procedur. Därför krävs koncentrering till ett fåtal kirurger.Fördelarna med tekniken är minskad blodförbrukning, kortare vårdtid och snabbare återhämtning för patienten.Samarbeten med etablerade centrum bör övervägas vid nyetablering för att förkorta inlärningskurvan och inte riskera patientsäkerheten.Minimally invasive mitral valve surgery - a technique for everyone? Less invasive procedures are being developed within all surgical specialties. In cardiac surgery, minimally invasive surgery is mainly suitable for mitral valve disease. It is a technically more complex procedure compared to standard cardiac surgery. All complex procedures have a learning curve and the surgeon must be exposed to a

Chloride ions play an important role in controlling excitability of principal neurons in the central nervous system. When neurotransmitter GABA is released from inhibitory interneurons, activated GABA type A (GABAA) receptors on principal neurons become permeable to chloride. Typically, chloride flows through activated GABAA receptors into the neurons causing hyperpolarization or shunting inhibiti

The paper’s title evokes a conversation; in fact it has been constructed like a joint revisitation of Bianca Beccalli’s forty years work on labour, gender, and politics, reconsidering old challenges and facing emergent ones. The paper deals with two levels of analysis: a historical and sociological interpretation of social movements, work, and politics on the one side, while dealing on the other s

The tight junction protein claudin-4 has been reported to be overexpressed in advanced ovarian cancer. We investigated the prognostic significance of claudin-4 overexpression and whether claudin-4 expression could predict platinum response in primary ovarian carcinoma (OC). Claudin-4 expression was evaluated by immunohistochemistry in a tissue microarray of 140 OCs. Multivariable Cox-regression mo

Alkaline sphingomyelinase cleaves phosphocholine from sphingomyelin, platelet-activating factor, lysophosphatidylcholine, and less effectively phosphatidylcholine The enzyme shares no structure similarities with acid or neutral sphingomyelinase but belongs to ectonucleotide pyrophosphatase/phosphodiesterase (NPP) family and therefore is also called NPP7 nowadays. The enzyme is expressed in the int

En diskussion rörande 2 Piers och The Glass Bubble av konstnären och landskapsarkitekten Monika Gora. Verken diskuteras i förhållande till platsbegreppet och mot en bakgrund av teoretiker och konstnärer som Miwon Kwon, Maurice Merleau-Ponty, Rosalind Krauss, Robert Smithson och Ana Mendieta.

We show that a quantum Szilard engine containing many bosons with attractive interactions enhances the conversion between information and work. Using an ab initio approach to the full quantum-mechanical many-body problem, we find that the average work output increases significantly for a larger number of bosons. The highest overshoot occurs at a finite temperature, demonstrating how thermal and qu

Aim: To evaluate aerobic exercise in migraine and co-existing tension-type headache and neck pain. Methods: Consecutively recruited persons with migraine and co-existing tension-type headache and neck pain were randomized into an exercise group or control group. Aerobic exercise consisted of bike/cross-trainer/brisk walking for 45 minutes, three times/week. Controls continued usual daily activitie

This study exploits policy reforms in Swedish primary care to examine the effect of pay-for-performance (P4P) on compliance with hypertension drug guidelines among public and private health care providers. Providers in regions with P4P are compared to providers in other regions in a difference-in-differences analysis using data from the Swedish Prescription Register for the period 2005-2013. The r

This article focuses on how the European Union's (EU) mediation activities during the Russia-Ukraine and Israel-Palestine conflicts are perceived by local elites. Our analysis is based on recent interviews with decision makers in Ukraine, Israel and Palestine. Consistent with this special issue, we investigate perceptions of EU roles, strategies and effectiveness. We suggest that the EU's relation