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BACKGROUND: There are important unmet clinical needs to develop cell enrichment technologies to enable unbiased label-free isolation of both single cell and clusters of circulating tumor cells (CTCs) manifesting heterogeneous lineage specificity. Here, we report a pilot study based on the microfluidic acoustophoresis enrichment of CTCs using the CellSearch CTC assay as a reference modality.METHODS

CDchorus and string orchestraI. Darkness shall cover the earth / Jesaja 60:2-3 ; II. How dark, O Lord / Thomas Morell ; III. A thick darkness / 2 Mosebok 10:21 ; IV. Total eclipse! / Newburgh Hamilton (efter John Milton)14 min

For mixed chorus and solo celloTexts from the poetry collections in the Lund University Special Collections archive “Witnessing Genocide"

We live in ‘Tomorrowland’; a land at the nexus of social science and natural science where the solution to our problems will be found tomorrow. The paper addresses the impossibility of international relations by proposing an alternative approach located in critical social theory. The paper utilises critical social theory to critique contemporary liberal assumptions and rationalisations of cultures

Salomon Smith Kammarmusikförening uppmärksammar tonsättaren och kompositionsprofessorn Staffan Storm i en porträttkonsert. Det blir ett uruppförande av stråkkvartetten Rifts and Pathways och ett urval av hans produktion de senaste 20 åren. Medverkar gör pianisterna Hans Pålsson och Francisca Skoogh, sopranen Amelia Jakobsson, Lunds Kammarsolister och Malmö Akademiska Kör under ledning av Daniel HaSalomon Smith Kammarmusikförening celebrates the composer and composition professor Staffan Storm with a portrait concert. It will feature the premiere performance of the string quartet "Rifts and Pathways" along with a selection of his works from the past 20 years. Participating artists include pianists Hans Pålsson and Francisca Skoogh, soprano Amelia Jakobsson, Lund Chamber Soloists, and Malmö

Vid regeringsbildningar har flera länder ett system där det enligt så kallade investiturregler krävs en omröstning i parlamentet. I och med 1974 års regeringsform är detta fallet även i Sverige. I den jämförande analys av olika länder som genomförs i detta kapitel visar det sig att ett sådant system är känsligt för förändringar av partisystemet. En genomgång av alla statsministeromröstningar i Sve

AimTo investigate the incidence rate of urinary tract infections (UTIs) among febrile infants aged ≤60 days before, during, and after the COVID-19 pandemic.MethodsWe conducted a retrospective study in 2 Swedish paediatric emergency departments between 2014 and 2022. We included full-term infants aged ≤60 days with fever without source. We calculated the annual incidence rate of UTI per 1000 births

Background: Insufficient physical activity is a growing public health concern and is closely linked to obesity in both adults and children. Swedish physical activity on prescription (PAP) is effective in increasing physical activity levels in adults, but knowledge about how PAP is used in paediatric healthcare is lacking. Therefore, this study aimed to explore experiences of working with PAP for c

The human cathelicidin LL-37 shows activity against microorganisms, but it is also cytotoxic to host cells. The CAMP gene codes for the LL-37 precursor hCAP18 which is processed extracellularly to active LL-37. It has previously been shown that vitamin D stimulates CAMP gene activity, but less information is available demonstrating that vitamin D also can increase hCAP18/LL-37 protein production.

Revealing the local structure information of relaxor ferroelectrics is necessary for a clear understanding of their structure-property relationships, especially the determination of the size of polar nanoregions (PNRs), which is still a long-standing challenge. In this work, the local structure of the pseudo-cubic solid solutions 0.60Bi(Mg1/2Ti1/2)O3-0.40PbTiO3 and 0.65Bi(Mg1/2Ti1/2)O3-0.35PbTiO3,

The reactivity of six MnIV-oxo complexes in C-H bond oxidation has been examined using a combination of kinetic experiments and computational methods. Variable-temperature studies of the oxidation of 9,10-dihydroanthracene (DHA) and ethylbenzene by these MnIV-oxo complexes yielded activation parameters suitable for evaluating electronic structure computations. Complementary kinetic experiments of

Much of our understanding of automatic control relies on descriptions and words. While rooted in mathematical theory, control is generally explained using examples and abstraction. Different terminology is used in different textbooks which can lead to inadvertent miscommunication. Here, the terminology introduced in the most frequently used textbooks is collated. The paper addresses lecturers, stu

In the generator coordinate method the wavefunctions are defined with respect to reference states that can indicate different shapes and deformations, which are examples of collective generator coordinates. In this work, we study the collective wavefunctions of Yrast states up to the terminating state of 50Cr using a recently introduced framework to calculate projected states of spins up to I = 14

Objective: Ovarian carcinoma (OvCa) is more common in the elderly, but also affects the adolescent and young adult (AYA) generation, which refers to those aged 15–39 years. Although the characteristics of OvCa may differ between AYAs and non-AYAs, limited information is currently available on differences in prognostic factors. Therefore, we herein investigated prognostic factors for and the progno

The Basilica group is a well-known 2-generated weakly branch, but not branch, group acting on the binary rooted tree. Recently, a more general form of the Basilica group has been investigated by Petschick and Rajeev, which is an s-generated weakly branch, but not branch, group that acts on the m-adic tree, for s,m ≥ 2. A larger family of groups, which contains these generalised Basilica groups, is

Despite a global consensus that fossil fuel subsidies should be reformed, limited progress has been made. The study assesses whether domestic political institutions insulating politicians from backlash and compensating those affected by reforms make subsidies easier to dismantle. It was found that proportional representation and corporatism were correlated with lower levels of fossil fuel subsidie

Organisms inhabiting highly seasonal environments must cope with a wide range of environmentally induced challenges. Many seasonal challenges require extensive physiological modification to survive. In winter, to survive extreme cold and limited resources, insects commonly enter diapause, which is an endogenously derived dormant state associated with minimized cellular processes and low energetic

Background: Taxi drivers in a Chinese megacity are frequently exposed to traffic-related particulate matter (PM2.5) due to their job nature, busy road traffic, and urban density. A robust method to quantify dynamic population exposure to PM2.5 among taxi drivers is important for occupational risk prevention, however, it is limited by data availability. Methods: This study proposed a rapid assessme