To identify credible causal risk variants (CCVs) associated with different histotypes of epithelial ovarian cancer (EOC), we performed genome-wide association analysis for 470,825 genotyped and 10,163,797 imputed SNPs in 25,981 EOC cases and 105,724 controls of European origin. We identified five histotype-specific EOC risk regions (p value

The first search for nonresonant Bc+→π+μ+μ- decays is reported. The analysis uses proton–proton collision data collected with the LHCb detector between 2011 and 2018, corresponding to an integrated luminosity of 9fb-1. No evidence for an excess of signal events over background is observed and an upper limit is set on the branching fraction ratio B(Bc+→π+μ+μ-)/B(Bc+→J/ψπ+)

A measurement of CP-violating observables in B± → D*K± and B± → D*π± decays is made where the photon or neutral pion from the D*→ Dγ or D*→ Dπ0 decay is not reconstructed. The D meson is reconstructed in the self-conjugate decay modes, D → KS0π+π− or D → KS0K+K−. The distribution of signal yields in the D decay phase space is analysed in a model-independent way. The measurement uses a data sample

Human rights concerns in relation to the impacts brought forth by artificial intelligence (‘AI’) have revolved around examining how it affects specific rights, such as the right to privacy, non-discrimination and freedom of expression. However, this article argues that the effects go deeper, potentially challenging the foundational assumptions of key concepts and normative justifications of the hu

In the last decade, businesses have played an increasingly significant role in promoting stability, democracy, and human rights, particularly concerning the United Nations Sustainable Development Goals, which emphasize peace, justice, and strong institutions. Consequently, there has been a greater focus on corporate social responsibility and corporate citizenship. Research has explored business mo

A search for CP violation in D0→KS0K+π− and D0→KS0K−π+ decays is reported. The search is performed using an unbinned model-independent method known as the energy test that probes local CP violation in the phase space of the decays. The data analysed correspond to an integrated luminosity of 5.4 fb−1 collected in proton-proton collisions by the LHCb experiment at a centre-of-mass energy of s = 13 T

The production of ψ(2S) mesons in proton-lead collisions at a centre-of-mass energy per nucleon pair of sNN = 8.16 TeV is studied with the LHCb detector using data corresponding to an integrated luminosity of 34 nb−1. The prompt and nonprompt ψ(2S) production cross-sections and the ratio of the ψ(2S) to J/ψ cross-section are measured as a function of the meson transverse momentum and rapidity in t

I antologin Antirasismer och antirasister: Realistiska utopier, spänningar och vardagserfarenheter utforskar 24 forskare hur motståndet mot olika former av rasism bedrivs och förkroppsligas bedrivs bland grupper av människor som på en mängd sätt, ofta motsägelsefullt, sällan framgångsrikt, men alltid envist och framåtblickande drömmer bortom rasismer. Antologin illustrerar antirasismens bredd, men

OBJECTIVE: To assess the effect of lateral episiotomy, compared with no episiotomy, on obstetric anal sphincter injury in nulliparous women requiring vacuum extraction.DESIGN: A multicentre, open label, randomised controlled trial.SETTING: Eight hospitals in Sweden, 2017-23.PARTICIPANTS: 717 nulliparous women with a single live fetus of 34 gestational weeks or more, requiring vacuum extraction wer

This paper examines the responses of Indigenous nations and European companies to new trading opportunities: the Cree nations with the Hudson's Bay Company (HBC) and the Khoe nations with the Dutch East India Company [Verenigde Oostindische Compagnie (VOC)]. This case study is important because of the disparate outcomes. Within a few decades the Cree standard of living had increased, while Khoe na

This chapter will deal with the advances and the innovative paradigms leading to reengineering the preservation of the myocardium and the potential of new upcoming reconditioning strategies to reduce BDD organ shortage and move toward DCD donation.

Die Folgen des Klimawandels für die Gesundheit sind bereits heute spürbar und als zunehmende Bedrohung für die Gesundheit in Österreich einzustufen. Die stärksten Gesundheitsfolgen mit breiter Wirkung sind durch Hitze zu erwarten. Veränderungen in Ökosystemen begünstigen zudem das Auftreten von Pollenallergien und durch Vektoren übertragene Infektionskrankheiten. Mit vermehrten Gesundheitsfolgen i

In this paper, we report the results from an experimental reproductive ethics study exploring questions about reproduction and parenthood. The main finding in our study is that, while we may assume that everyone understands these concepts and their relationship in the same way, this assumption may be unwarranted. For example, we may assume that if ‘x is y’s father’, it follows that ‘y is x’s child

The "International Society for Heart and Lung Transplantation Guidelines for the Evaluation and Care of Cardiac Transplant Candidates-2024" updates and replaces the "Listing Criteria for Heart Transplantation: International Society for Heart and Lung Transplantation Guidelines for the Care of Cardiac Transplant Candidates-2006" and the "2016 International Society for Heart Lung Transplantation Lis

Alzheimer's disease (AD) is a debilitating neurodegenerative disorder characterized by the accumulation of β-amyloid (Aβ) peptides and phosphorylated tau (P-tau) proteins in the brain, leading to cognitive decline and memory impairment. Despite extensive research, the exact mechanisms of AD pathogenesis remain elusive, and reliable biomarkers for early diagnosis and disease monitoring are still ne

Hazel (Corylus avellana) has been abundant in the vegetation of northern and central Europe since the early Holocene and has provided food and materials for humans ever since. Here we use stable carbon isotope (δ13C) values of hazelnut shells to infer woodland openness based on the premise of the “canopy effect”. It is well established that plants growing in dense, shaded forests have lower carbon

This paper reports cross-section measurements of ZZ production in pp collisions at s=13.6TeV at the Large Hadron Collider. The data were collected by the ATLAS detector in 2022, and correspond to an integrated luminosity of 29 fb−1. Events in the ZZ→4ℓ (ℓ=e, μ) final states are selected and used to measure the inclusive and differential cross-sections in a fiducial region defined close to the anal

A search for high-mass resonances decaying into a Formula Presented-lepton and a neutrino using proton-proton collisions at a center-of-mass energy of Formula Presented is presented. The full run 2 data sample corresponding to an integrated luminosity of Formula Presented recorded by the ATLAS experiment in the years 2015-2018 is analyzed. The Formula Presented-lepton is reconstructed in its hadro