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Endoscopic surveillance of columnar-lined esophagus - Frequency of intestinal metaplasia detection and impact of antireflux surgery
Objective To quantify the occurrence of intestinal metaplasia in columnar-lined esophagus (CLE) during endoscopic surveillance and to evaluate the impact of antireflux surgery on the development of intestinal metaplasia. Summary Background Data The malignant potential in segments of CLE is mainly restricted to those containing intestinal metaplasia. Patients with segments of CLE in which no intest
Transcranial Doppler pulsatility index is not a reliable indicator of intracranial pressure in children with severe traumatic brain injury
Background: The TCD-derived PI has been associated with ICP in adult studies but has not been well investigated in children. We examined the relationship between PI and ICP and CPP in children with severe TBI. Methods: Data were prospectively collected from consecutive TCD studies in children with severe TBI undergoing ICP monitoring. Ipsilateral ICP and CPP values were examined with Spearman corr
Loss-of-Function Mutation of the Galanin Gene is Associated with Perturbed Islet Function in Mice.
Epoxy-based production of wind turbine rotor blades: occupational contact allergies.
Malignancies during follow-up in an epidemiologically defined systemic lupus erythematosus inception cohort in southern Sweden
The objective of this study was to identify all malignancies in an inception cohort of SLE patients in southern Sweden and compare with the observed frequencies and spectrum of malignancies in the general population. All adult incidence cases of SLE in a defined population during the period 1981-1996 were retrieved from a prospective database and the cases were followed to endpoint or through 1998
Isolation, partial characterization and localization of integumental peroxidase, a stress-related enzyme in the skin of a teleostean fish (Cyprinus carpio L.)
Biochemical and immunological characteristics of peroxidase activity of the skin epithelium of common carp (Cyprinus carpio) were investigated and compared with peroxidase activity of blood cells. Skin as well as blood-borne peroxidases eluted from the Superdex column as a 135 kDa protein and both probably are tetrameric molecules. Skin peroxidase activity was characterized by a Vmax of 51.5 ± 1.3
Intermittency, metastability and coarse graining for coupled deterministic-stochastic lattice systems
We study the role of strong particle/particle interactions and stochastic fluctuations emanating from the micro-/sub-grid scale, in the context of a simple prototype hybrid system con- sisting of a scalar linear ordinary differential equation (ODE), coupled to a microscopic spin flip Ising lattice system. Due to the presence of strong interactions in the lattice model, the mean-field approximation
Identification of cytoskeletal components in pine ectomycorrhizas
Ectomycorrhizal associations were synthesized between pine seedlings and the fungi Suillus bovinus (L.) ex Fr. or Paxillus involutus (Batsch ex Fr.) Fr. Immunoblotting of polypeptides separated electrophoretically from crude tissue extracts revealed the abundant presence of tubulin and actin in ectomycorrhiza and lower amounts in the fungal strands surrounding the ectomycorrhizal roots. In ectomyc
Deep brain stimulation for Parkinson's disease: Patient selection and evaluation
Critical to the successful application of deep brain stimulation for the treatment Parkinson's disease is the proper selection of patients who will reliably benefit from this procedure and the successful evaluation of the responses obtained. This review will discuss the various factors influencing patient selection and summarize the recommended approach to patient assessment by using the Core Asse
Nurses´ experiences of strain and their reactions in the care of severely demented patients.
All nurses (N = 132) on the wards specializing in the care of the demented within a municipality were given two scales to assess their view of common patient actions and how easy they thought those actions were to deal with in the care situation, and to assess their emotional reactions during the provision of care. Also the Maslach burnout Inventory (MBI) and the Work Related Strain Inventory (WRS
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Hygroscopic growth and activation of HULIS particles: experimental data and a new iterative parameterization scheme for complex aerosol particles
The hygroscopic growth and activation of two HULIS (HUmic LIke Substance) and one Aerosol-Water-Extract sample, prepared from urban-type aerosol, were investigated. All samples were extracted from filters, redissolved in water and atomized for the investigations presented here. The hygroscopic growth measurements were done using LACIS (Leipzig Aerosol Cloud Interaction Simulator) together with a H
A methodology for enhanced flexibility of integrated assessment in agriculture
Agriculture is interrelated with the socio-economic and natural environment and faces increasingly the problem of managing its multiple functions in a sustainable way. Growing emphasis is on adequate policies that can support both agriculture and sustainable development. Integrated Assessment and Modelling (IAM) can provide insight into the potential impacts of policy changes. An increasing number
Displaced fractures of the neck of the radius in adults - An excellent long-term outcome
We have reviewed 20 women and three men aged 22 to 73 years, who had sustained a Mason type-lib fracture of the neck of the radius 14 to 25 years earlier. There were 19 patients with displacement of the fractures of 2 mm to 4 mm, of whom 13 had been subjected to early mobilisation and six had been treated in plaster for one to four weeks. Of four patients with displacement of 4 mm to 8 mm, three h
Soluble thrombomodulin activity and soluble thrombomodulin antigen in plasma.
Variable surface composition and radial interface formation in self-assembled free, mixed Ar/Xe clusters
Using photoelectron spectroscopy, we demonstrate how the self-assembling process of cluster formation in an adiabatic expansion leads to radial segregation and layering as well as to variable surface composition for binary Ar/Xe clusters. The radial structuring can be qualitatively understood from the different interatomic bonding strengths of the two components.
Local and landscape effects of organic farming on butterfly species richness and abundance
1. Agri-environmental schemes (AES) are commonly adopted in Europe to reduce the loss of farmland biodiversity. These schemes have, however, been criticized as not fulfilling this goal, partly because their effectiveness is thought to differ depending on external factors such as landscape heterogeneity, the focal organism and scale of application. 2. We used one AES, organic farming, as a landscap
Proteomic analysis identifies candidate proteins associated with distant recurrences in breast cancer after adjuvant chemotherapy.
Breast cancer is a heterogenous disease and it is of importance to select patients with regard to different prognosis and treatment sensitivity to individualize treatment regimes. In this study we successfully adapted a protein extraction protocol from mRNA extracted tumor samples enabling two-dimensional gel electrophoresis (2-DE) analysis of samples previously analyzed by cDNA microarray. The ai
Hydroxyisohexyl 3-cyclohexene carboxaldehyde-known as Lyral (R): quantitative aspects and risk assessment of an important fragrance allergen
Hydroxyisohexyl 3-cyclohexene carboxaldehyde, also known as Lyral(R), is a fragrance ingredient identified as the cause of contact allergic reactions in 2-3% of eczema patients undergoing patch testing. Lyral(R) has been included in the standard patch test series in many clinics due to its importance as an allergen. It has been used without restrictions in cosmetic products, until now. In the pres