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Visualizing, Analyzing and Managing the Scope of Software Releases in Large-Scale Requirements Engineering

Popular Abstract in English Large market-driven software companies face new challenges in requirements engineering and management that emerged due to their recent extensive growth. At the same time, the pressure generated by competitors’ and users’ expectations demands being more competitive, creative and flexible to more quickly respond to a rapidly changing market situation. In the pursuit of stLarge market-driven software companies face new challenges in requirements engineering and management that emerged due to their recent extensive growth. At the same time, the pressure generated by competitors’ and users’ expectations demands being more competitive, creative and flexible to more quickly respond to a rapidly changing market situation. In the pursuit of staying competitive in this co

Genome-wide discovery and verification of novel structured RNAs in Plasmodium falciparum

We undertook a genome-wide search for novel noncoding RNAs (ncRNA) in the malaria parasite Plasmodium falciparum. We used the RNAz program to predict structures in the noncoding regions of the P. falciparum 3D7 genome that were conserved with at least one of seven other Plasmodium spp. genome sequences. By using Northern blot analysis for 76 high-scoring predictions and microarray analysis for the

A moth pheromone brewery: production of (Z)-11-hexadecenol by heterologous co-expression of two biosynthetic genes from a noctuid moth in a yeast cell factory

Background: Moths (Lepidoptera) are highly dependent on chemical communication to find a mate. Compared to conventional unselective insecticides, synthetic pheromones have successfully served to lure male moths as a specific and environmentally friendly way to control important pest species. However, the chemical synthesis and purification of the sex pheromone components in large amounts is a diff

Evidence for a weakening relationship between interannual temperature variability and northern vegetation activity.

Satellite-derived Normalized Difference Vegetation Index (NDVI), a proxy of vegetation productivity, is known to be correlated with temperature in northern ecosystems. This relationship, however, may change over time following alternations in other environmental factors. Here we show that above 30°N, the strength of the relationship between the interannual variability of growing season NDVI and te

Promoted evolution of a shortened variant of heme A synthase in the membrane of Bacillus subtilis.

Bacillus subtilis heme A synthase is a membrane protein with 8 transmembrane segments. By using a two-step mutagenesis approach we have generated and selected a fully functional enzyme protein variant with a seven residue internal deletion. The biochemical properties of the shortened variant are similar to those of the normal enzyme. This could indicate that residue H209 in the mutant protein subs

Defect Structure of High-Temperature-Grown GaMnSb/GaSb

GaMnSb/GaSb(100) layers with embedded MnSb inclusions have been grown at 720 K using MBE technique. This paper presents the investigation of the defect structure of Ga1-xMnxSb layers with different content of manganese (up to x = 0.07). X-ray diffraction method using conventional and synchrotron radiation was applied. Dimensions and shapes of inclusions were detected by scanning electron microscop

Cenomanian-Campanian (Late Cretaceous) mid-palaeolatitude sharks of Cretalamna appendiculata type

The type species of the extinct lamniform genus Cretalamna, C. appendiculata, has been assigned a 50 Ma range (Albian-Ypresian) by a majority of previous authors. Analysis of a partly articulated dentition of a Cretalamna from the Smoky Hill Chalk, Kansas, USA (LACM 128126) and isolated teeth of the genus from Cenomanian to Campanian strata of Western Australia, France, Sweden, and the Western Int

Contested meanings in the Egyptian revolution

The 2011 Egyptian revolution was carried out under a banner notable for its distinct lack of divisive sectarian or political ideology. Two-and-a-half years later, the post-revolutionary scene looks strikingly different: a popularly supported military coup has ousted the country’s first democratically elected president, and the population is profoundly polarized. A common narrative is the so-called

Treatment outcome in T-cell lymphoblastic lymphoma in adults - a population-based study from the Swedish Lymphoma Registry

Background. T-cell lymphoblastic lymphoma (T-LBL) is a rare neoplasm of precursor lymphoblast origin, for which there is no standard treatment for adults. Results of current treatment strategies in selected populations do exist but are largely unreported for unselected series. Here, we aimed to investigate treatment outcome in a population-based cohort. Material and methods. Patients were identifi

The association between hip fracture and hip osteoarthritis: A case-control study

Background: There have been reports both supporting and refuting an inverse relationship between hip fracture and hip osteoarthritis (OA). We explore this relationship using a case-control study design. Methods: Exclusion criteria were previous hip fracture (same side or contralateral side), age younger than 60 years, foreign nationality, pathological fracture, rheumatoid arthritis and cases were

Vikings go multi-media

A review of the exhibition "Viking" (2013) at the National Museum of Denmark, later to travel to London and Berlin.

Surface composition of clean and oxidized Pd75Ag25(100) from photoelectron spectroscopy and density functional theory calculations

High resolution photoelectron spectroscopy and density functional theory calculations have been used to study the composition of clean and oxidized Pd75Ag25( 100). The results for the clean surface confirm earlier reports of surface segregation by Wouda et al. (1998), where the top most layers are rich in Ag. The Pd 3d core level component from the surface region is observed at higher binding ener

T3 levels in relation to prognostic factors in breast cancer: a population-based prospective cohort study

Background: The issue of a potential association between thyroid conditions/hormones and breast cancer has been studied extensively during the last decades but the results have been inconclusive and almost no studies have investigated breast cancer aggressiveness. We have previously found a positive association between prospectively measured levels of triiodothyronine (T3) and breast cancer incide

Combined performance tests before installation of the ATLAS Semiconductor and Transition Radiation Tracking Detectors

The ATLAS (A Toroidal LHC ApparatuS) Inner Detector provides charged particle tracking in the centre of the ATLAS experiment at the Large Hadron Collider (LHC). The Inner Detector consists of three subdetectors: the Pixel Detector, the Semiconductor Tracker (SCT), and the Transition Radiation Tracker (TRT). This paper summarizes the tests that were carried out at the final stage of SCT+TRT integra

Reduction in snow depth negatively affects decomposers but impact on decomposition rates is substrate dependent

Decomposition of organic matter in high latitude biomes makes a significant contribution to global fluxes of nutrients and carbon and is expected to accelerate due to climate change. The majority of studies have focused on decomposition during the growing season, but winter climate is expected to change dramatically. Furthermore, knowledge of the drivers of organic matter decomposition, such as li