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Extraction of circulating tumor cells from blood using acoustophoresis

We present, for the first time, separation of three different prostate cancer cell lines from leukocyte fractions by means of continuous flow acoustophoresis. This flow-through separation approach, which utilize acoustophoretic forces to extract CTCs from blood has a significant advantage over affinity based methods in the sense that it comprises a non-contact and label free separation of CTCs fro

Bacillus subtilis forms twisted cells with cell wall integrity defects upon removal of the molecular chaperones DnaK and trigger factor

The protein homeostasis network ensures a proper balance between synthesis, folding, and degradation of all cellular proteins. DnaK and trigger factor (TF) are ubiquitous bacterial molecular chaperones that assist in protein folding, as well as preventing protein misfolding and aggregation. In Escherichia coli, DnaK and TF possess partially overlapping functions. Their combined depletion results i

En svårnavigerad allians: En kvalitativ analys av Alliansen påverkan på medlemspartierna

Pre-electoral coalitions affect the involved parties in a unique and yet a quite undiscovered way. The largest and most successful pre-electoral coalition in Sweden was called the Alliance and was created prior to the 2006 parliament election.. Although pre-electoral coalitions are heavily underrepresented in coalition studies, there are existing hypotheses about the connection between parties ent

Modi operandi

India is forecast to overtake China as the world’s most populous country by 2023. Despite diligent efforts to gain independence from the British, today’s India faces new challenges: the creation of a national identity, achieving superpower status and the growth of Hindu nationalism. The aim of this essay is to investigate the use of political myths by Prime Minister Modi. Using speeches delivered

How is the problem of climate migration securitized?

This thesis analyzes the securitization discourse of climate migration as a study on the United Nations High Commissioner for Refugees, UNHCR. It’s based on material produced by UNHCR between the years 2017 - 2022. The study is accomplished with the 'What's the problem represented to be?' (WPR) approach, in combination with the securitization theory. In total are nine documents analyze

Slippery as an Eel. An analysis of the European Union's Eel Regulation Framework

This thesis uses an evaluative approach to analyse the European Union’s Eel Regulation Framework (ERF). By using theories on both legitimacy and posthumanism, the aim of the study is to answer the question of in which ways the ERF can be considered legitimate with both human and non-human stakeholders in mind. As environmental issues and biodiversity loss become increasingly severe, there is an ur

En jämlik och demokratisk klimatomställning – på vems villkor? En intervjustudie om klimatet, arbetarkollektivet och postpolitiken

While the climate crisis is gaining more attention, market mechanisms and individual behaviour changes seem to remain the dominant political answer to mitigate climate change. This thesis aims to examine how blue-collar labour unions in Sweden position themselves in the climate transition. Additionally, it explores ideological frontlines and identifies interest conflicts and power relations in the

Med kärleken på bröstet i diplomatins tjänst. En kontextbaserad ikonologisk analys av Erik XIV:s friarporträtt

This thesis is a case study of the only confirmed betrothal portrait in Swedish collections, sent by Erik XIV to Elisabeth I. The thesis examines the portrait in detail to find the symbolic differences and meanings in comparison to other portraits of the Swedish monarch. One of the main questions raised in the thesis is the question on which symbols can further deepen the understanding that this p

Prolonged repolarization in the early phase of ischemia is associated with ventricular fibrillation development in a porcine model

Background: Repolarization prolongation can be the earliest electrophysiological change in ischemia, but its role in arrhythmogenesis is unclear. The aim of the present study was to evaluate the early ischemic action potential duration (APD) prolongation concerning its causes, expression in ECG and association with early ischemic ventricular fibrillation (phase 1A VF). Methods: Coronary occlusion

Alkaline sphingomyelinase (NPP7) impacts the homeostasis of intestinal T lymphocyte populations

Background and aim: Alkaline sphingomyelinase (NPP7) is expressed by intestinal epithelial cells and is crucial for the digestion of dietary sphingomyelin. NPP7 also inactivates proinflammatory mediators including platelet-activating factor and lysophosphatidylcholine. The aim of this study was to examine a potential role for NPP7 in the homeostasis of the intestinal immune system. Methods: We qua

Kreditbetygets inverkan på investeringsbeslut och beteende

Titel: Kreditbetygets inverkan på investeringsbeslut och beteende Seminariedatum: 2023-01-11 Kurs: FEKH89 - Examensarbete i finansiering på kandidatnivå, 15 högskolepoäng Författare: Måns Brodin, Nahir Ertunga & Ludvig Hellman Handledare: Anamaria Cociorva Nyckelord: Kreditbetyg, obligationsmarknad, uppköp och sammanslagningar, företagsobligationer, financial constraints Forskningsfråga:Abstract Title: The impact of credit rating on investment decisions and behavior Seminar date: 2023-01-11 Course: FEKH89 – Bachelor’s thesis in financial management, 15 ECTS Authors: Måns Brodin, Nahir Ertunga & Ludvig Hellman Supervisor: Anamaria Cociorva Keywords: Credit ratings, bond market, mergers and acquisitions, corporate bonds, financial constraints Research question: Does the

When Political Interest is not Enough: A quantitative study on what deterred politically interested citizens from voting in the 2019 European Parliamentary election

The European Union (EU) has long suffered from a democratic deficit, something that has been highlighted many times by politicians, media and citizens alike. The EU has in turn tried to better its democratic standing by increasing the power of the European Parliament (EP) through the Treaty of Lisbon in 2009. This has however not increased turnout in the EP elections substantially, as only the lat

Hög tillgänglighet och god kvalitet? En intervjustudie om produktionsbaserad styrning inom offentlig vård

During the last decades, market-oriented policies have entailed significant changes within the Swedish public sector. In Västra Götalandsregionen, primary care clinics for physiotherapy since 2014 get funding based on collected contact points. The points are generated by patients visiting the clinics. Furthermore, the physiotherapists working at the clinics are assigned a daily target number. The

Recovery in mental illness: Focus on subjective perceptions of occupations in Clubhouses

The primary study aim was to explore which factors could predict recovery at baseline and follow- up, with occupational value, occupational balance, satisfaction with daily occupations, occupational engagement, and sociodemographic and clinical factors as predictors. A secondary aim was to investigate stability over time in personal recovery from baseline to a 9- month follow- up among people with

From Customer-, to Actor-, to Stakeholder Engagement : Taking Stock, Conceptualization, and Future Directions

Despite the significant strides made in the customer engagement literature, the need to understand any marketing actor’s engagement (vs. merely the customer’s) is increasingly recognized. Therefore, the budding actor engagement (AE) concept, which is commonly grounded in S-D logic, describes any marketing actor’s engagement, including that of customers, firms, employees, suppliers, and so on. Howe

Virtual diplomatic summitry

This chapter discusses the rise of virtual diplomatic summitry and its place in the digitalisation of diplomacy. Virtual diplomatic summitry refers to the diplomatic summit meetings that take place through technologies for virtual interaction such as videoconferencing tools, and that take place partly or completely in virtual venues. Virtualisation has been embraced as a solution to sustain instit