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Characterization of the agglomeration of roasted shredded cassava (Manihot esculenta crantz) roots

Roasted and granulated cassava roots flour, known as 'rale' in the south of Mozambique, is a common meal in sub-Saharan Africa and is consumed reconstituted with hot or cold water. In this work, analysis of rale was carried out with the aim of understanding what determines the agglomeration properties. Rale is agglomerated roasted cassava flour with about 95% of starch gelatinized. The pre-gelatin

Strategies to improve clinical research in surgery through international collaboration

More than 235 million patients undergo surgery every year worldwide, but less than 1% are enrolled in surgical clinical trials-few of which are international collaborations. Several levels of action are needed to improve this situation. International research collaborations in surgery between developed and developing countries could encourage capacity building and quality improvement, and mutually

Unbalanced N:P ratios and nutrient stress controlling growth and toxin production of the harmful dinoflagellate Prorocentrum lima (Ehrenberg) Dodge

The responses of the benthic marine dinoflagellate Prorocentrum lima to nutrient stress induced by unbalanced N:P ratios were the subject of this study. Batch cultures of P. lima cells were grown under NP sufficient (N as nitrate and ammonium) and deficient conditions, and the cell growth and toxicity were followed for eight weeks. P. lima grew slowly in all nutrient conditions and net growth rate

Finding effective pathways to sustainable mobility: bridging the science-policy gap.

This overview paper examines three areas crucial to understanding why, despite clear scientific evidence for the growing environmental impacts of tourism transport, there is large-scale inertia in structural transitions and a lack of political will to enact meaningful sustainable mobility policies. These include the importance of addressing socio-technical factors, barriers posed by “technology my

Breaking the stream ciphers F-FCSR-H and F-FCSR-16 in real time

The F-FCSR stream cipher family has been presented a few years ago. Apart from some flaws in the initial propositions, corrected in a later stage, there are no known weaknesses of the core of these algorithms. Two variants, F-FCSR-H and F-FCSR-16, were proposed in the eSTREAM project, and F-FCSR-H v2 is one of the ciphers selected for the eSTREAM portfolio. In this paper we present a new and sever

Prediction of Alzheimer disease in subjects with amnestic and nonamnestic MCI.

OBJECTIVE: To compare the predictive accuracy of β-amyloid (Aβ)1-42 and total tau in CSF, hippocampal volume (HCV), and APOE genotype for Alzheimer disease (AD)-type dementia in subjects with amnestic mild cognitive impairment (aMCI) and nonamnestic mild cognitive impairment (naMCI). METHODS: We selected 399 subjects with aMCI and 226 subjects with naMCI from a multicenter memory clinic-based coho

c-Jun N-Terminal Kinase Phosphorylation of MARCKSL1 Determines Actin Stability and Migration in Neurons and in Cancer Cells

Cell migration is a fundamental biological function, critical during development and regeneration, whereas deregulated migration underlies neurological birth defects and cancer metastasis. MARCKS-like protein 1 (MARCKSL1) is widely expressed in nervous tissue, where, like Jun N-terminal protein kinase (JNK), it is required for neural tube formation, though the mechanism is unknown. Here we show th

Spreading of α-synuclein in the face of axonal transport deficits in Parkinson's disease: A speculative synthesis.

Parkinson's disease (PD) is mainly attributed to degeneration of dopamine neurons in the substantia nigra, but its etiopathogenesis also includes impaired protein clearance and axonal transport dysfunction, among others. The spread of α-synuclein (α-syn) aggregates from one neuron to another, in a prion-like manner, is hypothesized to contribute to PD progression. Axonal transport is likely to pla

Actual and non-actual motion: why experientialist semantics needs phenomenology (and vice versa)

Experientialist semantics has contributed to a broader notion of linguistic meaning by emphasizing notions such as construal, perspective, metaphor and embodiment, but has suffered from an individualist concept of meaning and has conflated experiential motivations with conventional semantics. We argue that these problems can be redressed by methods and concepts from phenomenology, through a case s

Analysis and Modeling of Novel Low-Temperature SOFC With a Co-Ionic Conducting Ceria-Based Composite Electrolyte

In recent years, ceria-based composites (CBCs) have been developed as electrolytes for low-temperature solid oxide fuel cells. These materials exhibit extremely high ionic conductivities at 400-600 degrees C. It has also been found that both oxide ion and proton can be conducted in the CBC electrolytes, which makes such co-ionic conducting fuel cell distinct from any other types of fuel cells. In

Survey reproduction of defect reporting in industrial software development

Abstract in UndeterminedContext: Defect reporting is an important part of software development in-vivo, but previous work from open source context suggests that defect reports often have insufficient information for defect fixing. Objective: Our goal was to reproduce and partially replicate one of those open source studies in industrial context to see how well the results could be generalized. Met

Open Physical Models in Control Engineering Education

This paper discusses the significance of physical models in engineering education. Obvious assets, drawbacks and the educational role of such models are discussed, and the idea of 'open physical models' is introduced. A couple of sophisticated open physical models (an unmanned rotorcraft and an inverted pendulum robot), used in control engineering courses, are presented. Basic ideas and concepts,

WDM network re-optimization avoiding costly traffic disruptions

Network re-optimization is a process that must be triggered periodically in order to improve the inefficient resource allocation of online routing heuristics due to the uncertainty of online lightpath demand arrivals and departures. Network re-optimization involves two tasks: a) finding new lightpaths for a (sub)set of current demands, i.e. rerouting, and b) migrating the current traffic to the ne

How nanochannel confinement affects the DNA melting transition within the Poland-Scheraga model.

When double-stranded DNA molecules are heated, or exposed to denaturing agents, the two strands are separated. The statistical physics of this process has a long history and is commonly described in terms of the Poland-Scheraga (PS) model. Crucial to this model is the configurational entropy for a melted region (compared to the entropy of an intact region of the same size), quantified by the loop

Confined trisomy 8 mosaicism of meiotic origin: A rare cause of aneuploidy in childhood cancer.

Whether chromosome abnormalities observed in tumor cells may in some cases reflect low-grade somatic mosaicism for anomalies present already at zygote formation, rather than acquired somatic mutations, has for long remained a speculation. We here report a patient with Wilms tumor, where constitutional somatic mosaicism of trisomy 8 was detected in a previously healthy 2 ½-year-old boy. Single Nucl

A 1-1 MASH 2-D Vernier Time-to-Digital Converter with 2nd-order noise shaping

We use a 2-dimensional (2-D) Vernier gated-ring-oscillator (GRO) time-to-digital-converter (TDC) in a cascade structure (MASH), so that a larger raw quantization step can be allowed without sacrificing the final resolution performance. The 2-D approach effectively reduces the latency time under a large input, while the MASH structure provides a 2nd-order noise shaping that produces a lower in-band