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Mycobacterium bovis bacilli Calmette-Guerin regulates leukocyte recruitment by modulating alveolar inflammatory responses.

Leukocyte migration into the epithelial compartment is an important feature in the active phase of mycobacterial infections. In this study, we used the Transwell model to investigate the mechanisms behind mycobacteria-induced leukocyte recruitment and investigated the role of TLR2 and TLR4 in this process. Infection of epithelial cells resulted in significantly increased secretion of the neutrophi

Exact fidelity and full fidelity statistics in regular and chaotic surroundings

For a prepared state exact expressions for the time-dependent mean fidelity as well as for the mean inverse participation ratio are obtained analytically. The prepared state is taken as an eigenstate of the unperturbed system, and the studied fidelity is identical to the survival probability. The full distribution functions of fidelity in the long-time limit and of inverse participation ratio are

The proposed giant planet orbiting VB 10 does not exist

We present high-precision relative radial velocities of the very low mass star VB 10 that were obtained over a time span of 0.61 years as part of an ongoing search for planets around stars at the end of the main sequence. The radial velocities were measured from high-resolution near-infrared spectra obtained using the CRIRES instrument on the Very Large Telescope with an ammonia gas cell. The typi

Calorespirometry of terrestrial organisms and ecosystems.

Calorespirometry is the simultaneous measurement of heat and gas exchange from biological systems. Such measurements can be used to assess fundamental properties of many different types of systems from small ecosystems to isolated tissues. Techniques for calorespirometric measurements on terrestrial (non-aquatic) samples are described. Methods and models for evaluation of carbon conversion efficie

Surface Deposition and Phase Behavior of Oppositely Charged Polyion-Surfactant Ion Complexes. 2. A Means to Deliver Silicone Oil to Hydrophilic Surfaces

The delivery of emulsified silicone oil to hydrophilic silica surfaces by mixtures of cationic polysaccharides and SDS has been studied by in situ null ellipsometry, dynamic light scattering, and turbidity measurements. The emulsion contained silicone oil droplets with a hydrodynamic radius of 18 rim, stabilized by anionic and nonionic surfactants. The investigated polysaccharides were cat-guar an

Molecular basis of hereditary C1q deficiency-revisited: identification of several novel disease-causing mutations

C1q is the central pattern-recognition molecule in the classical pathway of the complement system and is known to have a key role in the crossroads between adaptive and innate immunity. Hereditary C1q deficiency is a rare genetic condition strongly associated with systemic lupus erythematosus and increased susceptibility to bacterial infections. However, the clinical symptoms may vary. For long, t

A Swedish National Prospective and Co-relative Study of School Achievement at Age 16, and Risk for Schizophrenia, Other Nonaffective Psychosis, and Bipolar Illness.

While cognitive ability is inversely associated with risk for schizophrenia (SZ), the association is less clear with other nonaffective psychoses (ONAP) and bipolar illness (BPI). Using national Swedish hospital registry data, we examined the prospective relationship between school achievement (SA) and development of SZ, ONAP, and BPI in 1800643 adolescents born 1972-1990. We used Cox proportional

Exploration of conformational flexibility and hydrogen bonding of xylosides in different solvents, as a model system for enzyme active site interactions

The predominantly populated conformation of carbohydrates in solution does not necessarily represent the biologically active species; rather, any conformer accessible without too large an energy penalty may be present in a biological pathway. Thus, the conformational preferences of a naphthyl xyloside, which initiates in vivo synthesis of antiproliferative glycosaminoglycans, have been studied by

Quantitative numerical analysis of flow past a circular cylinder at Reynolds number between 50 and 200

Results of numerical simulations are presented for flow past a stationary circular cylinder at low Reynolds numbers (Re=50-200). The simulations were carried out using a finite-volume code employing a fractional step method with second-order accuracy in both space and time. A sensitivity study on numerical parameters concerning the domain size, grid independence and time step resolution was carrie

Molecular structure of citric acid cross-linked starch films

The effect of citric acid (CA) on starch films has been examined. A new method to detect cross-linking of starch by CA in solution-cast films by molecular weight measurements is described. Furthermore, we managed to distinguished between free, mono- and di-esterified CA and quantify di-ester content within starch films by using a modification in the method of complexometric titration with copper(I

Power Based Multi-Cell Call Admission Control Scheme for Wideband-CDMA Systems

Wideband code division multiple access (WCDMA) systems are interference-limited. When a WCDMA system operates at nearly full capacity, admitting a new user may affect the stability of the system. Therefore, the proper call admission control (CAC) is crucial and should balance between quality of service (QoS) requirements for the new user as well as for the existing users and the required high capa

Water soluble contrast enema examination of the integrity of the rectal anastomosis prior to loop ileostomy reversal may be superfluous

Defunctioning loop ileostomy in low anterior resection (LAR) is routinely used to reduce consequences of anastomotic leakage. The purpose of this study was to analyze which examination technique is optimal for evaluating the integrity of the anastomosis prior to loop ileostomy reversal. Retrospective analysis of 95 patients who had been subjected to LAR at Helsingborg Hospital and SkAyenne Univers

Probing Time-Dependent Molecular Dipoles on the Attosecond Time Scale

Photoinduced molecular processes start with the interaction of the instantaneous electric field of the incident light with the electronic degrees of freedom. This early attosecond electronic motion impacts the fate of the photoinduced reactions. We report the first observation of attosecond time scale electron dynamics in a series of small-and medium-sized neutral molecules (N-2, CO2, and C2H4), m