Search results

Filter

Filetype

Your search for "*" yielded 528606 hits

The effects of experience on the development of sexual behaviour of males and females of the banded demoiselle (Calopteryx splendens).

Mate preferences can vary in the direction of the preference, as well as the strength of the preference, and both direction and strength of preference are known to be plastic in many species. Preferences might have a learned component, and current and past social context may influence an individual's choosiness. In the damselfly species Calopteryx splendens, females increase the strength of their

Dynamics of femoral bone remodelling in well fixed total hip arthroplasty. A 20-year follow-up of 20 hips.

The aim of our study was to investigate the dynamics of cortical thinning around well fixed cemented Muller straight stems without osteolysis at different time periods during long term follow-up. We investigated patients operated on for osteoarthritis with a cemented Muller straight stem, all with more than 15 years follow-up and no radiological signs of osteolysis. Cortical thinning in 20 THA hip

A randomized study of coronary artery bypass surgery performed with the Resting Heart™ System utilizing a low vs a standard dosage of heparin.

OBJECTIVES: Allogeneic blood transfusion and reoperation for postoperative bleeding after the coronary artery bypass grafting have a negative impact on the patient outcome. This study aimed at evaluating the effects of reduced doses of heparin and protamine on the patient outcome, using a heparin-coated mini-cardiopulmonary bypass (CPB) system. METHODS: Sixty patients undergoing elective first-ti

Simplicity of Skew Group Rings of Abelian Groups

Necessary and sufficient conditions for simplicity of a general skew group ring A?(sigma)G are not known. In this article, we show that a skew group ring A?(sigma)G, of an abelian group G, is simple if and only if its centre is a field and A is G-simple. As an application, we show that a transformation group (X, G), where X is a compact Hausdorff space acted upon by an abelian group G, is minimal

FVIII inhibitors: pathogenesis and avoidance.

The pathogenesis of inhibitory antibodies has been the focus of major scientific interest over the last decades and several studies on underlying immune mechanisms and risk factors for formation of these antibodies have been performed with the aim of improving the ability to both predict and prevent their appearance. It seems clear that the decisive factors for the immune response to the deficient

T Cells in Tumors and Blood Predict Outcome in Follicular Lymphoma Treated with Rituximab

Purpose: T cells influence outcome in follicular lymphoma, but their contributions seem to be modified by therapy. Their impact in patients receiving rituximab without chemotherapy is unknown. Experimental Design: Using flow cytometry, we evaluated the T cells in tumors and/or blood in a total of 250 follicular lymphoma patients included in two Nordic Lymphoma Group randomized trials that compared

Aberrantly activated claudin 6 and 18.2 as potential therapy targets in non-small-cell lung cancer

Claudins (CLDNs) are central components of tight junctions that regulate epithelial-cell barrier function and polarity. Altered CLDN expression patterns have been demonstrated in numerous cancer types and lineage-specific CLDNs have been proposed as therapy targets. The objective of this study was to assess which fraction of patients with non-small-cell lung cancer (NSCLC) express CLDN6 and CLDN18

Dosimetry for gadolinium neutron capture therapy (GdNCT)

Background Gadolinium (Gd) neutron capture therapy (GdNCT) is based on a neutron capture reaction (NCR) that involves emission of both short and long range products. The aim of this study was to investigate both the microscopic and macroscopic contributions of the absorbed dose involved in GdNCT. Methods Cylindrical containers with diameters 1-30 mm filled with a solution of Gd were irradiated wit

Selective oxidation of trimethylolpropane to 2,2-bis(hydroxymethyl)butyric acid using growing cells of Corynebacterium sp. ATCC 21245.

Multifunctional chemicals including hydroxycarboxylic acids are gaining increasing interest due to their growing applications in the polymer industry. One approach for their production is a biological selective oxidation of polyols, which is difficult to achieve by conventional chemical catalysis. In the present study, trimethylolpropane (TMP), a trihydric alcohol, was subjected to selective oxida

Genetic susceptibility to obesity and diet intakes: association and interaction analyses in the Malmö Diet and Cancer Study.

Gene-environment interactions need to be studied to better understand the obesity. We aimed at determining whether genetic susceptibility to obesity associates with diet intake levels and whether diet intakes modify the genetic susceptibility. In 29,480 subjects of the population-based Malmö Diet and Cancer Study (MDCS), we first assessed association between 16 genome-wide association studies iden

Conformational Entropies and Order Parameters: Convergence, Reproducibility, and Transferability

Conformational entropy provides major contributions to protein folding and functions, such as ligand binding, making it a potentially important driver of biologically relevant processes. NMR spectroscopy is a unique technique to estimate conformational entropy changes at atomic resolution, an approach that can be favorably augmented by comparisons with results from molecular dynamics (MD) simulati

Evaluation of MLH1 I219V Polymorphism in Unrelated South American Individuals Suspected of Having Lynch Syndrome.

Some single-nucleotide polymorphisms are associated with higher risk of colorectal cancer development and are suggested to explain part of the genetic contribution to Lynch syndrome. Aim: To evaluate the mutL homolog 1 (MLH1) I219V polymorphism in 124 unrelated South American individuals suspected of having Lynch syndrome, based on frequency, association with pathogenic MLH1 and mutS homolog 2 (MS

An evaluation of monitoring possibilities of argatroban using rotational thromboelastometry and activated partial thromboplastin time

Background: Rotational thrombelastometry/thrombelastography with ROTEM (R) and TEG (R) is becoming available bedside in an increasing number of intensive care units, where many patients with heparin-induced thrombocytopenia (HIT) are treated. The study has been performed in an effort to find out whether ROTEM (R) could be an alternative to activated partial thromboplastin time (aPTT) when argatrob

Inverse association of intellectual function with very low blood lead but not with manganese exposure in Italian adolescents

Background: Pediatric lead (Pb) exposure impacts cognitive function and behavior and co-exposure to manganese (Mn) may enhance neurotoxicity. Objectives: To assess cognitive and behavioral function in adolescents with environmental exposure to Pb and Mn. Methods: In this cross sectional study, cognitive function and behavior were examined in healthy adolescents with environmental exposure to metal

Theory-based interventions to reduce prescription of antibiotics-a randomized controlled trial in Sweden

Background. Upper respiratory tract infections (URTIs) are the most common reason for consulting a GP and for receiving an antibiotic prescription, although evidence shows poor benefit but rather increasing antibiotic resistance. Interventions addressing physicians have to take into consideration the complexity of prescribing behaviour. Objective. To study whether interventions based on behavioura

Absence of Epstein-Barr and Cytomegalovirus Infection in Neuroblastoma Cells by Standard Detection Methodologies.

Indications exist in the scientific literature that infection with human herpes family viruses may contribute to the pathogenesis of neuroblastoma (NB). However, systematic investigations regarding viral presence in NB cells have been scarcely reported. Here, the presence of DNA from Epstein-Barr virus (EBV) and human cytomegalovirus (HCMV) was assessed by PCR in 12 NBs, supplemented with RNA in s

Large inert carbon pool in the terrestrial biosphere during the Last Glacial Maximum

During each of the late Pleistocene glacial-interglacial transitions, atmospheric carbon dioxide concentrations rose by almost 100 ppm. The sources of this carbon are unclear, and efforts to identify them are hampered by uncertainties in the magnitude of carbon reservoirs and fluxes under glacial conditions. Here we use oxygen isotope measurements from air trapped in ice cores and ocean carbon-cyc