Hematopoietic stem cell lineage choices are decided by genetic networks that are turned ON/OFF in a switch-like manner. However, prior to lineage commitment, genes are primed at low expression levels. Understanding the underlying molecular circuitry in terms of how it governs both a primed state and, at the other extreme, a committed state is of relevance not only to hematopoiesis but also to deve

The aim of this study was to characterize the xylanolytic activity of Cryptococcus flavus isolate I-11. This microorganism was isolated from the Brazilian Cerrado, and enzyme plate assays showed that it also produces amylase and CMCase activity. The xylanolytic production of C. flavus isolate I-11 was improved by using a suitable combination of the carbon and nitrogen sources, reaching 130 U/mL A

The influence of major surgery on HIV disease progression and decline in CD4+ cell count was evaluated in 23 seropositive haemophilia patients. 24 HIV-infected patients served as non-operated controls. In addition, 32 age-matched seronegative subjects were included. The follow-up time was up to 5 years. During the course of the study, eight of the operated (35%) and 11 of the non-operated (48%) su

A blend of rapeseed and butter oil was transesterified using immobilized Thermomyces lanuginosus lipase (Lipozyme (R) TL IM) as catalyst. The reaction was followed by reversed-phase HPLC and the triacylglycerol peaks were tentatively identified from their elution times by calculating equivalent carbon numbers. Further identification was made using HPLC-electrospray tandem mass spectrometry. A few

Mitochondrial permeability transition (MPT) is a nonselective inner membrane permeabilization that contributes to neuronal cell death under circumstances such as brain trauma, ischemia, and hypoglycemia. Here we study the participation of MPT and the Bcl-2-sensitive apoptotic cell death pathway in glutamate receptor-mediated excitotoxicity. Intrastriatal infusions of the N-methyl-D-aspartate (NMDA

Smoking is a well-known risk factor for cardiovascular disease, although understanding of the pathophysiological mechanism is incomplete. The effect of heavy smoking, for more than 20 years and of 20 cigarettes per day, on aortic stiffness was studied in women (n = 23, age range 43-61 years) and men (n = 21, age range 43-61 years) who smoked but were otherwise healthy and compared with a healthy r

The European integration process both affirms and challenges gender relations in Europe. Yet integration theories have contributed little to understanding gender dynamics. The article presents a feminist critique of integration theories and argues that they have failed to look at how gender relations impact the 'driving forces' of European integration. This lacuna is attributed t t he implicit mal

ELT science drivers stress aperture, Strehl ratio, PSF definition and stability, field of view, wavelength range, flexibility, low polarisation and thermal emittance, auxiliary instruments, site and infrastructure. Applicable science categories are planets and planetary systems, stars and stellar systems, galaxies and galaxy clusters, and cosmology. ELT observations are needed for our own and othe

We investigated the orientation of juvenile pied flycatchers, Ficedula hypoleuca, during autumn migration in south Sweden using orientation cage experiments, to study the relative importance of visual and magnetic information at sunset. We performed cage tests under 12 experimental conditions that manipulated the geomagnetic and visual sunset cues available for orientation: natural clear skies in

Azimuthal correlations of jet-induced high-p(T) charged hadron pairs are studied at midrapidity in Au+Au collisions at root s(NN)=200 GeV. The distribution of jet-associated partner hadrons (1.0 < p(T)< 2.5 GeV/c) per trigger hadron (2.5 < p(T)< 4.0 GeV/c) is found to vary with collision centrality, in both shape and yield, indicating a significant effect of the nuclear collision medium on the jet

Objectives: The study examined the relation between daily workhours and the occurrence of neck-shoulder or back pain in physically demanding care work. Methods: Unpublished data were obtained from three intervention projects in care institutions. The projects had been conducted independently in Oslo (46 participants, 175 referents before and 158 referents after the intervention), Helsingborg (60

The character and quantity of dissolved organic carbon (DOC) were studied in nine small boreal streams and adjacent soils during two years, with focus on the spring snowmelt period. The streams cover a forest-wetland gradient, spanning from 0% to 69% wetland coverage. Lower values of the absorbance ratio measured at 254 nm and 365 nm (A(254)/A(365)), in both soil plots and streams, indicated that

The impedance at frequencies of 1-1000 kHz and dynamic bending storage modulus measured by the vibrating reed method were compared for potato tuber tissue, which had been processed by various methods. Raw potato tuber tissue strips were either heated for 30 min up to 100°C or frozen-thawed. Some samples were osmotically dehydrated in a mannitol solution up to a concentration of 0.7 mol/l. The elec

Amplified fragment length polymorphisms (AFLP) are dominant markers frequently used to build linkage maps where heterozygosity could be inferred by a backcross breeding strategy. In the present study, we describe the utilization of an unmanipulated great reed warbler, Acrocephalus arundinaceus pedigree to infer heterozygous genotypes of AFLP markers in order to map these markers to a partial linka