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Breast cancer hormone receptor levels and benefit from adjuvant tamoxifen in a randomized trial with long-term follow-up

BACKGROUND: Hormone receptor positivity predicts benefit from endocrine therapy but the knowledge about the long-term survival of patients with different tumor receptor levels is limited. In this study, we describe the 25 years outcome of tamoxifen (TAM) treated patients.PATIENTS AND METHODS: Between 1983 and 1992, a total of 4,610 postmenopausal patients with early-stage breast cancer were random

Evoking a Space Beyond Cinema

The exhibition features Aggregate States of Matters (2019), a film shot in the Peruvian Andes with the support of proyectoamil, in addition to a selection of her recent work. In 2002, Rosa Barba had one of her first exhibitions at the Sala Luis Miro-Quesada Garland in Miraflores (Lima) which started her enduring connection with Peru. During that visit Barba travelled extensively throughout the cou

Voice Engine & Hear, There Where the Echoes Are

Rosa Barba takes the components of cinema apart, giving each element a position in space and then starts playing with them. Designed as a promenade through the gallery, teeming with memories, the work offers a sensory experience that is further reinforced and enlivened with sound recordings of the vocal and musical performances.

Tuning Interactions in Correlated Electron Systems: From Two-Band Superconductivity to Quasi-1D Spin Chains

Neutron scattering techniques have been employed to investigate two key areas of condensed matter physics: superconductivity and quantum magnetism. The experimental studies span two distinct areas: two-band superconductors, where we explore the interplay between superconducting anisotropy and vortex structure, and quasi-one-dimensional (quasi-1D) spin chains, where we investigate the magnetic exci

The origin of the H αline profiles in simulated disc galaxies

Observations of ionized H αgas in high-redshift disc galaxies have ubiquitously found significant line broadening, σH α∼10 -100 km s-1 . To understand whether this broadening reflects gas turbulence within the interstellar medium (ISM) of galactic discs, or arises from out-of-plane emission in mass-loaded outflows, we perform radiation hydrodynamic simulations of isolated Milky Way-mass disc galax

EXPOSURE OF VOLUNTEERS IN MEDICAL RESEARCH - JUSTIFIED AND OPTIMISED?

Volunteers participating in medical research must be adequately protected. A volunteer can be a person undergoing treatment for an illness (a patient) or a healthy person. The radiological imaging and therapy procedures used could be routine or project-specific with different purposes. This contribution aims to explore the features and conditions of this planned exposure situation and to address s

In-cycle evolution of thickness and roughness parameters during oxygen plasma enhanced ZnO atomic layer deposition using in situ spectroscopic ellipsometry

We investigate the time evolution of ZnO thin film growth in oxygen plasma-enhanced atomic layer deposition using in situ spectroscopic ellipsometry. The recently proposed dynamic-dual-box-model approach [Kilic et al., Sci. Rep. 10, 10392 (2020)] is used to analyze the spectroscopic data post-growth. With the help of this model, we explore the in-cycle surface modifications and reveal the repetiti

Vestibular stimulation for promoting development and preventing morbidity in preterm infants

Objectives: This is a protocol for a Cochrane Review (intervention). The objectives are as follows:. To assess the benefits and harms of vestibular stimulation compared to standard care or non-vestibular stimulation for physical and neurological development in preterm infants. To assess whether the effects of vestibular stimulation differ according to gestational age at birth; the type, frequency,

A conceptual framework for landscape-based environmental risk assessment (ERA) of pesticides

While pesticide use is subject to strict regulatory oversight worldwide, it remains a main concern for environmental protection, including biodiversity conservation. This is partly due to the current regulatory approach that relies on separate assessments for each single pesticide, crop use, and non-target organism group at local scales. Such assessments tend to overlook the combined effects of ov

Signal amplification in molecular sensing by imprinted polymers

In the field of sensing, the development of sensors with high sensitivity, accuracy, selectivity, sustainability, simplicity, and low cost remains a key focus. Over the past decades, optical and electrochemical sensors based on molecular imprinting techniques have garnered significant attention due to the above advantages. Molecular imprinting technology utilizes molecularly imprinted polymers (MI

Development of Optically Communicating Nanowire-based III-V Devices : Optical broadcasting for artificial neural networks

Denna avhandling presenterar utvecklingen och studiet av en flexibel och kiselchip-kompatibel integration av III–V nanotrådsbaserade (NW) optoelektroniska komponenter i nätverkskretsar, där kommunikation sker genom utsändning av ljussignaler. Detta innefattar en undersökning av hur neurala bearbetningsbeteenden kan efterliknas med hjälp av fotoniska kretsar på chip. Både experimentella resultat soThis thesis presents the development and study of a flexible and Silicon-chip compatible integration of III–V nanowire (NW) optoelectronic components in network circuits, where communication is done via the broadcasting of light signals. This includes an investigation into how neural processing behaviours can be emulated using on-chip photonic circuits. Both experimental works that demonstrate the

Long-term pain and health economic outcomes in adults receiving multidisciplinary CBT for chronic pain : the role of psychological inflexibility

BACKGROUND: Little is known about whether the recommended, non-pharmacological treatments for chronic pain yield reductions in healthcare utilization, social costs and increased productivity in actual practice.METHODS: The primary aim of this study ( n = 232) was to conduct secondary analyses of health economic outcomes using data from national registries combined with clinical outcome data from a

RIP #almedalen: The rise and fall of the hashtag of a Swedish democracy festival

Democracy festivals are events that aim to strengthen democracy by engaging citizens, politicians and organisations in dialogue and provide a more equal access to the agenda. In recent years, social media have become important arenas for agenda building, supposedly equalising the access to such processes. This article uncovers patterns of activity and visibility in agenda building through an actor

Responsibilization and Gender Inequality : Navigating Structural Barriers in the Swedish Digital Games Industry

The Swedish digital games industry portrays itself as inclusive and egalitarian, yet structural inequalities persist, particularly for women. Despite progress in gender equality in Sweden, the industry remains male-dominated, with women comprising only 24% of the workforce in 2023. Female game developers often face exclusion, sexism, and limited career opportunities, being relegated to less presti

Ptychographic reconstructions performed in real time and offline have equivalent quality

Ptychography is a burgeoning imaging technique that enables high-resolution, lensless reconstruction of complex samples by analysing overlapping diffraction patterns, making it invaluable in fields like materials science, biology, and nanotechnology. Real-time ptychographic reconstructions are gaining interest in the scientific community as they provide immediate feedback. Yet their potential to r

Zero waste for all? : Sustainable practices in a small-scale zero waste community from a universal design perspective

Since 2003, Kamikatsu in Japan has established a sustainable zero-waste practice that has achieved a recycling rate exceeding 80%. By exploring how the community has shaped itself around the zero-waste concept, this paper aims to enhance our understanding of zero waste in practice from a universal design perspective. Interviews and photo documentation were used to gather data. The zero-waste conceSince 2003, Kamikatsu in Japan has established a sustainable zero-waste practice that has achieved a recycling rate exceeding 80%. By exploring how the community has shaped itself around the zero-waste concept, this paper aims to enhance our understanding of zero waste in practice from a universal design perspective. Interviews and photo documentation were used to gather data. The zero-waste conce

Social Preferences and Environmental Externalities

Standard economic theory assumes that consumers ignore the externalities they create, such as emissions from burning fossil fuels and generating waste. In an incentivized study (N = 3, 718), we find that most people forgo substantial gains to avoid imposing negative externalities on others. Using administrative data on household waste, we show a clear link between such prosociality and waste behav

Imprecision plateaus in quantum steering

We study tests of quantum steering in which the trusted party does not have perfect control of their measurements. We report on steering inequalities that remain unaffected when introducing up to a threshold magnitude of measurement imprecision. This phenomenon, which we call an imprecision plateau, thus permits a departure from the standard assumption of idealized measurements without incurring a

Semidefinite Relaxations for High-Dimensional Entanglement in the Steering Scenario

We introduce semidefinite programming hierarchies for benchmarking relevant entanglement properties in the high-dimensional steering scenario. Firstly, we provide a general method for detecting the entanglement dimensionality through certification of the Schmidt number. Its key feature is that the computational cost is independent of the Schmidt number under consideration. Secondly, we provide a m