PurposeTo map T1 and the local flip angle (B1+) in human brain using a single MP3RAGE sequence with 3 rapid acquisitions of gradient echoes (RAGEs).Theory and methodsA third RAGE with a relatively high flip angle was appended to an MP2RAGE sequence. Through curve fitting and a rational approximation for small flip angles and short TR, closed form solutions for T1 and B1+ were derived. The influenc

Western South Africa between Cape Town and the Namibian border hosts many dyke swarms that strike broadly to the NW and NNW, towards the reconstructed plume-centre of the c. 130 Ma Parana-Etendeka Large Igneous Province (LIP) but are undated. U-Pb ID-TIMS age determinations on baddeleyite from two NNW-striking dykes (~100 km long) parallel to the Namaqualand coast yield 487 ± 8 Ma and 482 ± 7 Ma a

Cognitive trajectories vary greatly across older individuals, and the neural mechanisms underlying these differences remain poorly understood. Here, we investigate the cognitive variability in older adults by linking the influence of white matter microstructure on the task-related organization of fast and effective communications between brain regions. Using diffusion tensor imaging and electroenc

In the wake of the current environmental crisis, scholars of late antique Christianity are beginning to study Christian attitudes towards the natural world. How did the early Christians relate to their environment? This article explores perceptions of trees, surveying the writings of Tertullian, Basil of Caesarea, and Sozomen the historian. What did an arboreal plant do, according to patristic aut

The fragmentation rate function connects the fundamental drop breakup process with the resulting drop size distribution and is central to understanding or modeling emulsification processes. There is a large interest in being able to reliably measure it from an emulsification experiment, both for generating data for validating theoretical fragmentation rate function suggestions and as a tool for st

BACKGROUND: Breathlessness is a multidimensional symptom prevalent in elderly affecting many aspects of life. We aimed to determine how different dimensions of breathlessness are associated with physical and mental quality of life (QoL) in elderly men.METHODS: This was a cross-sectional, population-based analysis of 672 men aged 73 years in a Swedish county. Breathlessness was assessed using Dyspn

Efficiently planned railway maintenance helps ensure reliable infrastructure and the proper functioning of its components. The Swedish Transport Administration delegates maintenance work to contractors through a tender process. This paper analyses differences in communication and collaboration in the planning and execution of maintenance under two contract types. A document review and interviews w

The purpose of the study is to explore how a multinational enterprise can use social innovations to drive change and solve grand challenges in an emerging market context. This paper brings market-shaping literature into a sustainability context, particularly by studying the implementation of social innovations in an emerging market context. Specifically, the study involves an in-depth qualitative

The retail industry has witnessed fast international growth during the last couple of decades and various models and theories have been proposed for how to best explain the process and why some firms succeed while others fail. Recently researchers have argued that not only do we need more in-depth longitudinal case studies, and case studies from different sectors, but we also need to understand th

Background: α-synuclein (α-syn) aggregation can lead to degeneration of dopaminergic neurons in the substantia nigra pars compacta (SNpc) as invariably observed in patients with Parkinson's Disease (PD). The co-chaperone DNAJB6 has previously been found to be expressed at higher levels in PD patients than in control subjects and was also found in Lewy bodies. Our previous experiments showed that k

Land-use intensification of agricultural soils and increased occurrence and intensity of extreme weather events like drought periods are two of the main threats responsible for soil biodiversity declines. These changes in soil biodiversity can alter ecosystem functions performed especially by soil microbial communities that could further contribute to those threats. Microbial diversity is an essen