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Idelalisib in relapsed/refractory diffuse large B-cell lymphoma : results from a Nordic Lymphoma Group phase II trial
Linear strain and stress potential parameters for the three fundamental band to band transitions in β-Ga2O3
We report the strain and stress relationships for the three lowest energy direct band to band transitions at the Brillouin zone center in monoclinic β-Ga2O3. These relationships augment four linear perturbation parameters for situations, which maintain the monoclinic symmetry, which are reported here as numerical values obtained from density functional theory calculations. With knowledge of these
EU missions and operations: practices of learning lessons in the CSDP
A Global Map of COVID-19 Vaccine Acceptance Rates per Country: An Updated Concise Narrative Review
The delay or refusal of vaccination, which defines vaccine hesitancy, is a major challenge to successful control of COVID-19 epidemic. The huge number of publications addressing COVID-19 vaccine hesitancy necessitates periodic review to provide a concise summary of COVID-19 vaccine acceptance rates worldwide. In the current narrative review, data on COVID-19 vaccine acceptance rates were retrieved
Research priorities to address the global burden of chronic obstructive pulmonary disease (COPD) in the next decade
Background: The global prevalence of chronic obstructive pulmonary disease (COPD) has increased markedly in recent decades. Given the scarcity of resources available to address global health challenges and respiratory medicine being relatively under-invested in, it is important to define research priorities for COPD globally. In this paper, we aim to identify a ranked set of COPD research prioriti
Childhood cancer survivorship care during the COVID-19 pandemic : an international report of practice implications and provider concerns
Purpose: Long-term follow-up (LTFU) care is essential to optimise health outcomes in childhood cancer survivors (CCS). We aimed to assess the impact of the COVID-19 pandemic on LTFU services and providers. Methods: A COVID-19 working group within the International Late Effects of Childhood Cancer Guideline Harmonization Group (IGHG) distributed a questionnaire to LTFU service providers in 37 count
Maskerad bemanning i svensk byggindustri
Simulation of phase evolution in a Zr-based glass forming alloy during multiple laser remelting
Additive manufacturing by laser-based powder bed fusion is a promising technique for bulk metallic glass production. But, reheating by deposition of subsequent layers may cause local crystallisation of the alloy. To investigate the crystalline phase evolution during laser scanning of a Zr-based metallic glass-forming alloy, a simulation strategy based on the finite element method and the classical
Optimal Design of Electronic Bouncers for Long-Pulse High-Power Modulators
Modern high-voltage high-power pulsed modulators typically generate pulses by discharging energy stored in one or more capacitor banks into the load. The capacitor discharge manifests itself as output pulse droop which must be compensated for. To eliminate such droop, modulators utilizing pulse transformers require external circuitry and, typically, passive resonant bouncer circuits are used. For
Helga Leitner, Jamie Peck and Eric Sheppard (eds.) 2020: Urban Studies Inside/Out: Theory, Method, Practice. London: Sage
Obesity Partially Mediates the Diabetogenic Effect of Lowering LDL Cholesterol
OBJECTIVE LDL cholesterol (LDLc)-lowering drugs modestly increase body weight and type 2 diabetes risk, but the extent to which the diabetogenic effect of lowering LDLc is mediated through increased BMI is unknown. RESEARCH DESIGN AND METHODS We conducted summary-level univariable and multivariable Mendelian randomization (MR) analyses in 921,908 participants to investigate the effect of lowering
From 'digital' to 'smart': upgrading the city
In this paper we seek to reflect on the way in which 'digital cities' later re-emerge as 'smart cities' (both in terms of the approaches and also the actual cities) and what lessons can be learned about the role of ICTs in how they shape urban space. We will focus on looking at how the lack of understanding of the city as a 'place' is often a common factor in the lack of longevity in 'digital city
Non-Invasive Characterization of Atrio-Ventricular Properties during Atrial Fibrillation
The atrio-ventricular (AV) node is the primary regulator of ventricular rhythm during atrial fibrillation (AF). Hence, ECG based characterization of AV node properties can be an important tool for monitoring and predicting the effect of rate control drugs. In this work we present a network model of the AV node, and an associated workflow for robust estimation of the model parameters from ECG. The
Dacarbazine-vindesine versus dacarbazine-vindesine-cisplatin in disseminated malignant melanoma. A randomised phase III trial
In a multicentre phase III study of disseminated malignant melanoma performed in Sweden and Norway, 326 patients were randomised to receive treatment with the combination dacarbazine [DTIC] (D) and vindesine (V) with or without the addition of cisplatin (P). D was given intravenously (i.v.) at a dose of 250 mg/m2 days 1-5 every 4 weeks and V was given i.v. at a dose of 3.0 mg/m2 day 1 weekly. P wa
COVID-19 in pregnancy—characteristics and outcomes of pregnant women admitted to hospital because of SARS-CoV-2 infection in the Nordic countries
Introduction: Population-based studies about the consequences of SARS-CoV-2 infection (COVID-19) in pregnancy are few and have limited generalizability to the Nordic population and healthcare systems. Material and methods: This study examines pregnant women with COVID-19 in the five Nordic countries. Pregnant women were included if they were admitted to hospital between 1 March and 30 June 2020 an
Blylav återfunnen i Padjelanta nationalpark efter 79 år
Padjelanta nationalpark har en exceptionellt artrik och fort farande till stor del okänd lavflora inklusive många sällsynta eller rödlistade arter. Lavforskaren Gunnar Degelius hittade 1941 den rödlistade blylaven på ett klippblock vid fjället Unna Duvgge på sydvästra stranden av Virihaure vilket är den nordligaste lokalen för arten i Sverige. Sommaren 2020 återfann vi blylaven efter 79 långa år,
Structures of activin ligand traps using natural sets of type I and type II TGFβ receptors
The 30+ unique ligands of the TGFβ family signal by forming complexes using different combinations of type I and type II receptors. Therapeutically, the extracellular domain of a single receptor fused to an Fc molecule can effectively neutralize subsets of ligands. Increased ligand specificity can be accomplished by using the extracellular domains of both the type I and type II receptor to mimic t
The European External Action Service: a melting pot of EU foreign policy practice
Optimised versus standard automated peritoneal dialysis regimens pilot study (OptiStAR) : A randomised controlled crossover trial
Background: The continuous global rise of end-stage kidney disease creates a growing demand of economically beneficial home-based kidney replacement therapies such as peritoneal dialysis (PD). However, undesirable absorption and exposure of peritoneal tissues to glucose remain major limitations of PD. Methods: We compared a reference (standard) automated PD regimen 6 × 2 L 1.36% glucose (76 mmol/L