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RNA sequencing-based single sample predictors of molecular subtype and risk of recurrence for clinical assessment of early-stage breast cancer

BackgroundMultigene expression assays for molecular subtypes and biomarkers can aid clinical management of early invasive breast cancer. Based on RNA-sequencing we aimed to develop single-sample predictor (SSP) models for conventional clinical markers, molecular intrinsic subtype and risk of recurrence (ROR).MethodsA uniformly accrued breast cancer cohort of 7743 patients with RNA-sequencing data

The democratic potential of politically and socially oriented CSOs : The case of North Macedonia

The chapter investigates the democratic potential of politically and socially oriented civil society organizations (CSOs) to engage citizens and articulate citizens’ interests in the policymaking process in North Macedonia. To do so, the chapter reports on the responses of CSOs to a survey which sought information on the extent to which organizations involve members in organizational activities an

Otillgänglig tillgänglighet : En rättssociologisk kartläggning av normer inom strategisk fysisk planering i Skåne

Rapporten, som författats vid Rättssociologiska institutionen på Lunds universitet på uppdrag av Region Skåne, syftar till att nå kunskap om hur tillgänglighetsarbete praktiseras inom strategisk fysisk planering i Skåne, utifrån ett rättssociologiskt normperspektiv. I ljuset av Håkan Hydéns normmodell (2002) – som beskriver att en norm förutsätter kunskap, möjlighet och vilja för att omsättas i ha

Nulla Poena Sine Lege Parlamentaria? Democratic Legitimacy and European Penal Law

Introduction: Questioning the Democratic Legitimacy of European Penal Law In Western political systems it is elemental that legislation must have a democratic source in order to be legitimate. Above all, democratic legitimacy is regarded as important with reference to penal legislation, since penal power is paradigmatically the most intrusive form of political power. Therefore, it is generally ack

Shaping the future of European epilepsy research : Final meeting report from EPICLUSTER

Collaboration is essential to the conduct of basic, applied and clinical research and its translation into the technologies and treatments urgently needed to improve the lives of people living with brain diseases and the health professionals who care for them. EPICLUSTER was formed in 2019 by the European Brain Research Area (EBRA) to support the coordination of epilepsy research in Europe. A key

Utilising phase diagram to understand barley starch microsphere preparation in an aqueous two-phase system

In this work, a waxy barley starch-PEG aqueous two-phase system (ATPS) phase diagram was constructed, and starch microsphere preparation was explored at different phase diagram positions. The aim was to investigate starch-PEG ATPS phase behaviour and relate this to starch crystallisation and microsphere formation. The hypothesis was that phase diagram position would influence the starch microspher

Physical Demands of Tennis Across the Different Court Surfaces, Performance Levels and Sexes: A Systematic Review with Meta-analysis

BackgroundTennis is a multidirectional high-intensity intermittent sport for male and female individuals played across multiple surfaces. Although several studies have attempted to characterise the physical demands of tennis, a meta-analysis is still lacking.ObjectiveWe aimed to describe and synthesise the physical demands of tennis across the different court surfaces, performance levels and sexes

Soft Power

This chapter examines the National Security Strategy and the repositioning of public diplomacy as a tool of national security and prosperity. This includes William Hague’s plans to make the FCO the best diplomatic institution in the world, as well as the series of structural reforms that positioned GREAT as the new oversight board for public diplomacy. It includes a case study of the soft power st

Targeted National Promotion

This chapter examines the change of government in 2010 and the impact of austerity savings. It demonstrates the ways in which limited funding and the opportunities afforded by high-profile events such as the Pope’s visit to the UK, the Royal Wedding and the 2012 Olympics shaped an environment conducive to the creation of the GREAT branding campaign. The chapter concludes with a discussion of the w

Barn i migrationsprocessen

I den här rapporten beskriver vi hur rättstillämpningen, såsom de n framkommer i 100 av Migrationsverkets beslut, 17 av myndighetens akter samt 20 tjänstemäns intervjusvar, stämmer överens med de rättigheter asylsökande barn har enligt barnkonventionen och de tilläggsprotokoll till konventionen som Sverige har ratificerat. Frågeställning en utgår från det uppdrag vi fick av barnrättighetsutredningI den här rapporten beskriver vi hur rättstillämpningen, såsom de n framkommer i 100 av Migrationsverkets beslut, 17 av myndighetens akter samt 20 tjänstemäns intervjusvar, stämmer överens med de rättigheter asylsökande barn har enligt barnkonventionen och de tilläggsprotokoll till konventionen som Sverige har ratificerat. Frågeställning en utgår från det uppdrag vi fick av barnrättighetsutredning

Study of the Interfacial Oxidation of InP Quantum Dots Synthesized from Tris(dimethylamino)phosphine

InP quantum dots (QDs) are the most competitive in terms of environmentally friendly QDs. However, the synthesis of InP QDs requires breakthroughs in low-cost and safe phosphorus precursors such as tri(dimethylamino)phosphine [(DMA)3P]. It is found that even if the oxygen is completely avoided, there are still oxidation state defects at the core/shell interface of InP QDs. Herein, the record-break