Megalencephalic leukoencephalopathy with subcortical cysts (MLC), is a congenital leukodystrophy with childhood onset. It is an extremely rare genetic disorder of the brain that affects less than 1 per 1,000,000 live births. Patients typically present macrocephaly during early childhood and later develop symptoms like decreased motor and cognitive functions, and epileptic seizures, all of which us

Structural rearrangements in small Pt crystals, which were initiated by the incident electron beam, have been studied in real time with a 400 kV high-resolution electron microscope equipped with TV image viewing and videorecording facilities. The phenomena of crystal growth, particle coalescence and atomic clouds above particular surfaces were recorded at the atomic level and have been analysed us

Small metal particles (

Increasing renewable integration is posing new challenges to reliability of power networks. One of these challenges is to restart the power network and energize power transformers in the event of a blackout. Grid forming converters can provide a potential solution to this issue because they can be controlled as independent, self starting, voltage sources. This study analyzes and compares four grid

Rationale: We recently demonstrated that patients with coronary artery disease (CAD) and obstructive sleep apnea (OSA) carrying the tumor necrosis factor-alpha (TNF-α) A allele had increased circulating TNF-α levels compared with the ones carrying the TNF-α G allele. In the current study, we addressed the effect of TNF-α (-308G/A) gene polymorphism on circulating TNF-α levels following continuous

Great reed warblers, Acrocephalus arundinaceus,1 and great snipes, Gallinago media,2 exhibit a diel cycle in flight altitudes—flying much higher during the day than the night—when performing migratory flights covering both night and day. One hypothesis proposed to explain this behavior is that the birds face additional heating by solar radiation during daytime and hence must climb to very high, an

Most proteins fold into characteristic three-dimensional structures. The rate of folding and unfolding varies widely and can be affected by variations in proteins. We developed a novel machine-learning-based method for the prediction of the folding rate effects of amino acid substitutions in two-state folding proteins. We collected a data set of experimentally defined folding rates for variants an

Connected and automated vehicles (CAVs) will be a key component of future cooperative intelligent transportation systems (C-ITS). Since the adoption of C-ITS is not foreseen to happen instantly, not all of its elements are going to be connected at the early deployment stages. We consider a scenario where vehicles approaching a traffic light are connected to each other, but the traffic light itself

This timely book addresses the political under-representation of women and over-representation of men, both in the UK and internationally. It does so by bringing together perspectives from political science and sociolinguistics to analyse the relationship between gender and language in a variety of political spheres. Specifically, it investigates how both women and men use language and interact ac

BACKGROUND: Numerous laboratory tests are used in the diagnosis and management of patients with diabetes mellitus. The quality of the scientific evidence supporting the use of these assays varies substantially. An expert committee compiled evidence-based recommendations for laboratory analysis in patients with diabetes. The overall quality of the evidence and the strength of the recommendations we

Frequency-domain electromagnetic induction (EMI) methods are commonly used to map vast areas quickly and with minimum logistical efforts. Unfortunately, they are often characterized by a very limited number of frequencies and severe ill-posedness. On the other hand, electrical resistivity tomography (ERT) approaches are usually considered more reliable; for example, they do not require specific ca

This thesis investigates Swedish crisis management. This thesis aims to contribute to crisis research by providing critical perspectives on the role of knowledge in crisis management settings. The papers in this thesis stem from empirical studies of the major cases of Swedish crisis management during the last decade, including the Swedish refugee crisis in 2015, the wildfires in 2018, and the Covi

A large gold cluster with the formula Au55[(C6H5)3P]12Cl6, was imaged with a high-resolution transmission electron microscope (HRTEM) and a proposed model was confirmed. Growth of gold crystals of approximately 4.0 nm size could be followed, row by row of atoms, with the use of a low light level TV camera and on-line image processing.

Krishantering och förebyggande arbete inför naturkatastrofer, som i detta examensarbete avgränsas till tsunamis, har identifierats som bristande genom tiderna. Här studeras tsunamikatastroferna i Indiska Oceanen 2004 och Japan 2011 för att identifiera brister hos varningssystemen som används för att skydda samhällena som befinner sig i dessa riskzoner och dess befolkning. Först visade det sig att

Invisible Committee, ‘the name given to a collective voice bent on denouncing contemporary cynicism and reality’ (described by one of the members of the anonymous group), published a text in 2007 that hypothesised the ‘imminent collapse of capitalist culture’ that would arise from new waves of social contestation. Under the title The Coming Insurrection the text (denounced as a manual for terroris

Background: Prostate cancer (PC) survivors may potentially use substances to cope with psychological distress or poorly controlled physical symptoms. Little is known, however, about the long-term risks of alcohol use disorder (AUD) or drug use disorders in men with PC. Methods: A national cohort study was conducted in Sweden of 180-189 men diagnosed with PC between 1998 and 2017 and 1 801 890 age-

About the book:Fourteen scholars who work on campus or in the theater address this issue of what it means to play offstage. With their individual definition of what “offstage” could mean, the results were, predictably, varied. They employed a variety of critical approaches to the question of what happens when the play moves into the audience or beyond the physical playhouse itself? What are the so

Background Statistical analyses of clinical data are a cornerstone in understanding pathomechanisms of disorders. In rare disorders, cross-sectional datasets of sufficient size are usually not available. Taking AA amyloidosis as an example of a life-threatening rare disorder resulting from of uncontrolled chronic inflammation, we propose techniques from time series analysis to predict organ respon