Framtidens digitalisering av tumöranalyser för bättre behandling och prognos Läkarkonsten är på väg att få fler redskap för att individanpassa cancerbehandlingar och få en bättre patientöverlevnad. Intressant nog kan vi i framtiden komma till att förutsäga tumörers svar på behandling utifrån en matematisk algoritm som med hjälp av uppmätta gen- och proteinnivåer skattar halten av olika immuncelleIntroduction: There is a shortcoming in current breast cancer treatment, where some patients get overtreated leading to unnecessary side effects and others will not respond to the indicated treatment. Immune infiltration appears to have potential to become an important parameter when predicting how the tumour will respond to certain treatments, prognosing the survival rates in different subgroups

Punctuality is a key factor in railway operations and is affected by both primary and secondary delays to differing degrees. Being able to separate these two types of delays is very important when simulating operations, and when conducting punctuality improvement efforts. However, it is not easy to estimate the relative proportions of primary versus secondary delays using historical data. In this

I Sverige är befolkningen mån om att köpa second hand, återvinna, sortera sopor, äta vegetariskt och så vidare. När det däremot gäller den politiska sfären finns det ett Miljöparti som kämpar för att hålla sig ovan riksdagens 4% spärr. Syftet med uppsatsen är att undersöka varför Miljöpartiet har svårt att driva miljöfrågan i den politiska sfären trots goda förutsättningar. Med utgångspunkt i Nikl

Newly qualified social workers (NQSW) in Sweden are often thrust into statutory social work. In the context of statutory social work, social workers need to navigate a professional rationale, on which the social work profession rests, with an organizational rationale, on which the welfare organization – the social services – rests. This is due to the fact that social workers often are reliant on w

The development and expansion of artificial intelligence have significant potential to benefit humanity; however, the risks posed by AI-related tools have also become a growing concern over the past decade. From the standpoint of human rights violations AI-related bias, discriminatory practices, data protection practices and violations or potential infringements on fundamental rights are some of t

The unsustainable work environment of social workers in Swedish social services has been highlighted frequently through various reports. According to various reports, first-line managers in social services seem to play an important role in how to approach an unsustainable work environment. The aim of this study was to analyze how first-line managers in Swedish child social services reflect on soci

The honeybee gut microbiome is thought to be important for bee health, but the role of the individual members is poorly understood. Here, we present closed genomes and associated mobilomes of 102 Apilactobacillus kunkeei isolates obtained from the honey crop (foregut) of honeybees sampled from beehives in Helsingborg in the south of Sweden and from the islands Gotland and Åland in the Baltic Sea.

Lakes are important natural resources and carbon gas emitters and are undergoing rapid changes worldwide in response to climate change and human activities. A detailed global characterization of lakes and their long-term dynamics does not exist, which is however crucial for evaluating the associated impacts on water availability and carbon emissions. Here, we map 3.4 million lakes on a global scal

Jet impingement cooling is an effective way for thermal management in electronics, prevailed over many other single heat transfer modes. In general, jet arrays are better than a single jet, enhancing jet cooling performance. However, the performance of jet arrays is strongly dependent on the jet configurations, e.g., adjacent jet interval and hole-to-surface distance. Thus, in this study, jet impi

As the number of antennas scales up, research efforts have been directed towards finding decentralized receiver solutions for multi-antenna architectures. In a recent paper, a novel matrix decomposition - the WAX decomposition - was proposed, which has direct bearing on characterizing the level of decentralization that is possible if the complexity of the decentralized processing is limited. Howev

Funding is central to the viability of a class action regime. Wherever class actions have been adopted, legislators have used an array of design points to shape regimes that facilitate the requisite economic enablers and conditions. Yet one facet that has received insufficient attention in research and reforms is the potential of a public funder to advance collective claims and promote public inte

Background and purpose — A doubling of arthroscopic meniscal procedures was observed in Denmark from 2000 to 2011, but arthroscopic meniscal procedures for degenerative meniscal tears are no longer recommended. We performed an updated investigation of Danish meniscal procedure trends in the private and public healthcare sectors in Denmark from 2006 to 2018, including trends for other arthroscopic

Recent studies based on photometry from the Transiting Exoplanet Survey Satellite (TESS) have suggested that the dayside of KELT-1b, a strongly irradiated brown dwarf, is significantly brighter in visible light than what would be expected based on Spitzer observations in the infrared. We observed eight eclipses of KELT-1b with CHaracterising ExOPlanet Satellite (CHEOPS) to measure its dayside brig

Previous studies of Thomas Pynchon’s works have made progress in defining numerous aspects of what could be construed as the Pynchonian worldview. However, they have mainly identified them in general, visual terms, separated from the level of the direct experience of his characters. The process of perception is important in philosophical inquiry, but its role in the worldview of Pynchon’s works ha

The Swedish government has a national goal that states all violence against women will cease to exist. This goal is a part of a national strategy that will take place between the years 2017-2026. One of the main focuses of the strategy is to work with the perpetrator to make sure the acts of violence are not repeated. Another main focus is to shed light on societal norms regarding masculinity and