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A Monte Carlo Study of Titrating Polyelectrolytes in the Presence of Salt

Monte Carlo simulations have been performed for two simple models of a titrating polyelectrolyte: (i) a rigid rod and (ii) a freely jointed chain. Both models have fixed bond lengths, and the polyelectrolyte charges interact through a screened Coulomb potential. Chains consisting of 80-1000 monomeric units have been studied at three salt concentrations: 0.001, 0.01, and 0.1 M. Conformational prope

Lateral fluid percussion brain injury : a 15-year review and evaluation

This article comprehensively reviews the lateral fluid percussion (LFP) model of traumatic brain injury (TBI) in small animal species with particular emphasis on its validity, clinical relevance and reliability. The LFP model, initially described in 1989, has become the most extensively utilized animal model of TBI (to date, 232 PubMed citations), producing both focal and diffuse (mixed) brain inj

PLATO as it is : A legacy mission for Galactic archaeology

Deciphering the assembly history of the Milky Way is a formidable task, which becomes possible only if one can produce high-resolution chrono-chemo-kinematical maps of the Galaxy. Data from large-scale astrometric and spectroscopic surveys will soon provide us with a well-defined view of the current chemo-kinematical structure of the Milky Way, but it will only enable a blurred view on the tempora

Perivascular Neurotransmitter Regulation of Cerebral Blood Flow

Cerebral circulation is regulated by two principal systems: autonomic and sensory nerves from cranial ganglia and intrinsic innervation of the cerebral microcirculation. The sympathetic innervation originates from the superior cervical ganglion and stores noradrenaline and neuropeptide Y. It has a role in the extreme limits of the autoregulation. The parasympathetic innervation of the brain circul

Multimodal prominences : Exploring the patterning and usage of focal pitch accents, head beats and eyebrow beats in Swedish television news readings

Facial beat gestures align with pitch accents in speech, functioning as visual prominence markers. However, it is not yet well understood whether and how gestures and pitch accents might be combined to create different types of multimodal prominence, and how specifically visual prominence cues are used in spoken communication. In this study, we explore the use and possible interaction of eyebrow (Facial beat gestures align with pitch accents in speech, functioning as visual prominence markers. However, it is not yet well understood whether and how gestures and pitch accents might be combined to create different types of multimodal prominence, and how specifically visual prominence cues are used in spoken communication. In this study, we explore the use and possible interaction of eyebrow (

Comparison of MRD monitoring by IG/TR rearrangement and BCR/ABL1 transcript in PH+ pediatric acute lymphoblastic leukemia patients treated with imatinib in the EsPhALL study

Background. In the European Study for Pediatric Ph+ ALL (EsPhALL), a total of 128 patients aged 1 to 18 years diagnosed with ALL and evidence of t(9;22)(q34;q11) received post-Induction Imatinib on top of BFM high risk chemotherapy backbone, either in Good Risk (GR) (after randomization, n=58) or in Poor Risk (PR) (n=70), as defined according to early response to the National induction treatment.

Neutron reflectometry with the Multi-Blade 10B-based detector

The Multi-Blade is a boron-10-based gaseous detector developed for neutron reflectometry instruments at the European Spallation Source in Sweden. The main challenges for neutron reflectometry detectors are the instantaneous counting rate and spatial resolution. The Multi-Blade has been tested on the CRISP reflectometer at the ISIS Neutron and Muon Source in the UK. A campaign of scientific measure

The effects of aerobic exercise and the impact of migraine and co-existing tension-type headache and neck pain

The overall aims of this thesis were to investigate the effects of an aerobic exercise program and the impact of migraine and co-existing TTH and NP in persons with these combined conditions. This thesis is based on four studies.In study I, a new questionnaire, Impact of Migraine, TTH and NP (Impact M-TTH-NP), was developed. This questionnaire covered pain, triggers, psychosocial,socioeconomic and

The Land-Labour Hypothesis in a Settler Economy : Wealth, Labour and Household Composition on the South African Frontier

Traditional frontier literature identifies a positive correlation between land availability and fertility. A common explanation is that the demand for children as labour is higher in newly established frontier regions compared to older and more densely populated farming regions. In this paper we contribute to the debate by analysing the relationship between household composition and land availabil

Curating social image : Experimental evidence on the value of actions and selfies

We manipulate the information subjects can share on the web concerning socially sensitive actions (public good contribution) and visibility (selfie) to determine the effect on social image, as captured by the price subjects demand for publication. Our novel design incorporates aspects of social media interaction including limited anonymity and the possibility to manipulate published information in

Early cerebral hyperglycolysis after subarachnoid haemorrhage correlates with favourable outcome

BACKGROUND: Intracerebral microdialysis (MD) was applied in patients with severe subarachnoid haemorrhage treated in a neurosurgical intensive care unit in order to explore their cerebral energy metabolism.METHOD: Brain MD fluid levels of glucose, lactate and pyruvate were measured for 3 to 12 days in 20 patients and 2,635 hourly samples were analysed. The MD data were related to computerized tomo

Low and high circulating cortisol levels predict mortality and cognitive dysfunction early after stroke

OBJECTIVE: Elevated cortisol levels are associated with confusion and poor outcome after stroke. Dehydroepiandrosterone sulphate (DS), the most abundant adrenal androgen may act as an anti-glucocorticoid. An altered regulation of these steroids may affect numerous brain functions, including neuronal survival. The purpose of this study was to investigate serum cortisol and DS levels and the cortiso