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Conifer-feeding bark beetles are important herbivores and decomposers in forest ecosystems. These species complete their life cycle in nutritionally poor substrates and some can kill enormous numbers of trees during population outbreaks. The Eurasian spruce bark beetle (Ips typographus) can destroy >100 million m3 of spruce in a single year. We report a 236.8 Mb I. typographus genome assembly usin

The European grapevine moth, Lobesia botrana, uses (E,Z)-7,9-dodecadienyl acetate as its major sex pheromone component. Through in vivo labeling experiments we demonstrated that the doubly unsaturated pheromone component is produced by ∆11 desaturation of tetradecanoic acid, followed by chain shortening of (Z)-11-tetradecenoic acid to (Z)-9-dodecenoic acid, and subsequently introduction of the sec

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Den svenska demokratin firar hundraårsjubileum. År 1921 hölls första riksdagsvalet med allmän och lika rösträtt. Hur såg kampen för kvinnors rösträtt ut i Hässleholms kommun? Här porträtteras: Nelly Thüring, uppvuxen i Mala och verksam som fotograf i Lund från sekelskiftet 1900, en av de fem första kvinnorna i riksdagen; Maria Schalin, medlem i Frisinnade Kvinnor, propa­gerade för kvinnors rösträt

This open access book describes methods of mortality forecasting and discusses possible improvements. It contains a selection of previously unpublished and published papers, which together provide a state-of-the-art overview of statistical approaches as well as behavioural and biological perspectives. The different parts of the book provide discussions of current practice, probabilistic forecastin

In this paper I address two concerns with Kelly Trogdon’s grounding mechanism view, i.e. the idea that metaphysical explanation can be modeled on causal-mechanical explanation. The first concern threat-ens to undermine the unity that grounding-mechanical explanations imposes on metaphysical explana-tion; and the second concern requires the grounding mechanic to put forth a formal condition on grouIn this paper I address two concerns with Kelly Trogdon’s grounding mechanism view, i.e. the idea that metaphysical explanation can be modeled on causal-mechanical explanation. The first concern threatens to undermine the unity that grounding-mechanical explanations imposes on metaphysical explanation; and the second concern requires the grounding mechanic to put forth a formal condition on ground

Anxiety is a natural emotional response to stress, fear, or danger. Then, it is no wonder why some are experiencing anxiety in the face of the climate crisis. Although not a clinical diagnosis, climate anxiety – and related terms like eco-anxiety, ecological grief, and solastalgia – describes the distress, grief, or anger caused by environmental destruction occurring now, or presumed to occur in t

Kermack et al. (1934) proposed the cohort explanation in their analysis of the aggregated mortality decline in England, Wales, Scotland, and Sweden. Their conclusion was that reductions in the death rates of the various age groups attained at any particular time depended primarily on the individuals’ date of birth, and only indirectly on the particular year under consideration. The essential effec

During the early COVID-19 pandemic, many countries took compulsory measures to combating the virus’s spread, while Sweden took a more voluntary approach. This led to polarized reactions in the international media, with some praising it and others proclaiming it disastrous. Using the concept of “moral panic” I examine how actors within the global media environment portrayed Swedes as a deviant popu

Amyloid plaques composed of Aβ amyloid peptides and neurofibrillary tangles are a pathological hallmark of Alzheimer Disease. In situ identification of early-stage amyloid aggregates in Alzheimer’s disease is relevant for their importance as potential targets for effective drugs. Synchrotron-based infrared imaging is here used to identify early-stage oligomeric/granular aggregated amyloid species

Background: Chronic kidney disease, cardiovascular disease, and cognitive dysfunction are common in the elder population. There is evidence of a connection between these conditions, possibly by a shared vascular pathogenesis. Processing speed is commonly impaired in cerebrovascular disease. Methods: The data was obtained from the population based study “Good aging in Skåne” (GÅS), and included 905

The incretin glucagon-like peptide-1 (GLP-1) is a gut hormone but also locally produced in pancreatic islets. We evaluated effects of GLP-1 on the insulin response to a gradual increase in glucose in mice within physiological levels. We initially developed a glucose ramp technique in mice. Glucose levels were slowly increased by 0.2 mmol/l/min for 40 min under control conditions, during intravenou