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Arithmetic Reduction of the Static Power Consumption in Nanoscale CMOS

The power consumption is becoming a major obstacle in future circuit design. Referring to Moore's law, by adding more functionality in an exponential way, we will also increase the total power consumption in the same pace. VLSI design has traditionally been concerning the dynamic power consumption as the limiting factor in low power system design. Today, when the feature sizes are in the nano-mete

Stochastic Models Involving Second Order Lévy Motions

This thesis is based on five papers (A-E) treating estimation methods for unbounded densities, random fields generated by Lévy processes, behavior of Lévy processes at level crossings, and a Markov random field mixtures of multivariate Gaussian fields. In Paper A we propose an estimator of the location parameter for a density that is unbounded at the mode. The estimator maximizes a modified lik

Dynamic Isotropy in 6-DOF Kinematically Constrained Platforms by Three Elastic Nodal Joints

The principle of kinematic design has a wide range of applications e.g. from optical mirror mounts to parallel robots. Despite the importance of dynamic isotropy in the optimization of dynamic performance, a thorough analysis of dynamic isotropy in different kinematic arrangements has not yet been addressed in the literature. Dynamic isotropy, leading to equal eigenfrequencies, is a powerful optim

Sadegh Zibakalam: Anti-Americanism at a 'Dead End' in Iran

The country’s preeminent public intellectual says anti-Americanism has run its course in the Islamic republic. Hardliners will try to roll back any openings, but in the long run, the country will find itself in a better place politically, economically and socially.

Development of Computational Methods for Cancer Research: Strategies for closing the feedback loop in omics workflows

Popular Abstract in Swedish Den mänskliga kroppen är ett komplext maskineri med en rad olika reglersystem och kontrollmekanismer. Flera grenar av modern biomedicinsk forskning riktar sig mot olika nivåer av detta komplexa maskineri. En av dessa grenar heter genomik, som ärläran om hur den genetiska koden som finns i varenda cell av en organism används och regleras. Slutförandet av Human Genome ProAs the ultimate workhorses of the living things, proteins undergo significant regulatory activity throughout the lifetime of a cell or an organism. Many complex diseases effect the protein composition, expression or modification in the cells or tissues they arise in. It is then no surprise that proteomics is a field full of promise, one which is expected to generate significant insights towards fu