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Optisk DNA-kartläggning – en metod tillämpad cancerdiagnostik? Akut lymfatisk leukemi (ALL) och akut myeloisk leukemi (AML) är sjukdomar som i hög grad är orsakade av så kallade strukturella variationer i gener. Dessa typer av leukemi är bland de vanligaste cancertyperna som drabbar barn. Det är därför av stort intresse att kunna detektera dessa förändringar för att kunna erbjuda en så bra behandPediatric leukemias are one of the most common types of cancer diagnosed in children. Acute lymphoblastic leukemia (ALL) is the most common form of leukemia in children, and acute myeloid leukemia (AML) is the second most reoccurring type of leukemia in pediatric diagnosis. It has previously been found that structural variations are an important underlying mechanism leading to these diseases. Fluo

MicroProteins are small, separately expressed parts of a larger protein and able to interfere with the full-length protein’s function. To enable modulation of hormone perception, microProteins were designed from the ethylene, cytokinin and gibberellin receptors. The protein isoforms designed to function as microProteins were overexpressed in Arabidopsis. Overexpression of a shortened gibberellin r

Val som görs tidigt i en designprocess kan vara avgörande. De dikterar många av de begränsningar och friheter som konstruktörer har i senare skeden av processen. Informerade beslut är därmed viktiga i detta skede. Med den ökande beräkningskraften hos moderna datorer använder fler och fler konstruktörer CFD-programvara för att utforma och utvärdera prestanda hos turbopumpar. Simuleringarna gör det Choices made in the early stages of a design process are crucial. They dictate many of the limitations and freedoms the designer has in later stages of the design. Informed decisions are therefore crucial at this stage. With the increasing computational power of modern computers, more and more designers utilise CFD software to design and evaluate performance of turbopumps. The simulations allow th

Development of a novel gene therapy against cancer Despite tremendous efforts and achieved advances, cancer is still the leading cause of death worldwide, which underlines the need to develop novel curative approaches. In the past decade, we witnessed the rapid development of immunotherapy – novel treatment strategies based on harnessing the patient´s very own immune system to fight cancer. Altho

Syftet med studien är att undersöka hur det fysiska och det digitala flödet för sterilhantering av instrument kombineras på ett sjukhus. Detta för att kunna utläsa hur dessa två flöden stödjer varandra mot riskförebyggande för att tillgodose behoven för ett framgångsrikt tjänstemöte.

Under de senaste åren och i samband med pandemin har det skett en ökad motreaktion till urbaniseringen. Teknologins framsteg har gjort att fler kan arbeta på distans och man prioriterar sitt boende och livskvalité på ett nytt sätt. Allt fler väljer att flytta utanför städerna för att bo billigare, större och nära naturen. Ruralismen ställer högre krav på infrastrukturer och kollektivtrafiken och

Within a not-too-distant future, Sweden is believed to face a surge in demand for electricity. The purpose of this thesis is to examine the economic aspects of small modular reactors (SMR), as one possible solution for Sweden’s coming energy needs. SMR are a new form of nuclear reactors, modularly constructed in a factory and small enough to be shipped to the site where they are to be installed. H

The rapid evolution of modern chipsets and sensors has led to most modern smartphones are capable of providing an Augmented Reality (AR ) experience. Recent advancements in web development have made it possible to leverage the mobile device’s AR capabilities and deliver immersive content directly in the browser. The web-based immersive content may constitute a future platform for instructions and

The goal was to perform a feasibility study on an additive manufactured thermoplastic nose-cone hull design for an autonomous underwater vehicle SAM. Where feasibility includes the technical, economic and sustainable aspect in the analysis. The additive manufacturing process enables customization, modularity, design freedom, structure optimization, cost efficient low volume and tool less manufactu

In July 2013 Croatia has become the latest member state to join the European Union. Access to this single European area, in particular, to economically well-developed countries with a more robust labor market and a higher standard of living than Croatia resulted in intensification of emigration from Croatia. This has particularly affected young, well-educated Croats; ambitious, unsatisfied with th

Implant loosening is a recurring problem in the field of orthopedics, typically resulting in a physical and financial burden for the patient. Proper integration of orthopedic implants within host bones is a fundamental requirement for the successful function and limited risk of failure of implants which, in-vivo, must support various loading conditions. This implant fixation is highly dependent on

This thesis aims to create a social guide for Lund University Accommodation (LUACC) to facilitate more open, safe and equal student accommodation, namely corridors. A cultural analytical exploration and discussion of the nature of the corridor provide the legitimation and justification of this guide. The rationale of the thesis stemmed from my curiosity about the corridor as a nexus point of indiv

Denna studie undersöker svensk-kubanska pars upplevelser av att leva i en transnationell relation. Fokus ligger på de fördomar och utmaningar som paren mött både på Kuba och i Sverige. Uppsatsen bygger på fem intervjuer med svenskar och kubaner som bor i Sverige och lever/har levt i en transnationell relation. Studien utforskar mer specifikt hur ideal om autonomi, självförverkligande och individua

The present thesis develops around the topic of child custody removal among migratised families in Catalonia, Spain. Child custody removal is a common practice from Childcare: it takes place when the State assesses that the best interest of the minor is to remain a part of their family. In 2020, a group of mothers who currently live in Barcelona and have migrated from non-European countries starte

The issues concerning the health and social care for the elderly is a subject which needs to be dedicated more time. Increased life expectancy in Sweden places demands on an increased attention on issues concerning elderly care. The purpose of this study is to shed light on different perspectives on the best way to create dignified aging, according to politicians in the Swedish parliament. This to

Ehlers-Danlos syndrom (EDS) är en ovanlig ärftlig sjukdom som påverkar bindväven och leder till flera olika symptom med påverkan i hela kroppen. Framför allt ses överrörlighet och smärta i leder, trötthet och en generell benägenhet till smärta och ångest, men symptomen kan variera mycket från person till person. Eftersom symptomen även kan ses vid många andra sjukdomar blir det ofta svårt för läkaBackground: Ehlers-Danlos Syndrome (EDS) is a hereditary disease that affects the connective tissue of the body. Common symptoms include stretchy and frail skin, hypermobility, joint pain and chronic fatigue, although the disease is associated with many more symptoms. Because of this, the disease often remains un- or misdiagnosed. The interactions between patients with EDS and healthcare professio

This thesis examines conspiracy theories and the scepticism that exists concerning Covid-19 vaccines, although science today is easily accessible. The discussion revolves around what scepticism is present in anti-vaccine forums, why some people distance themselves from the current scientific debate and why they turn to internet forums to gather information. These questions will be discussed throug

Denna studie innefattas av en kvalitativ visuell analys av sex videor delade av Donald Trump på Twitter under hans tid som president 2016–2020. Samtliga delar av analysmaterialet innehar drag av populärkulturens och i synnerhet reality-genrens logik, narrativ och roller. Studiens syfte är att belysa hur dessa karaktärsdrag präglat Trumps sätt att kommunicera och i förlängningen det politiska samta

This thesis explores two interrelated issues when it comes to traditional alcohol in Tanzania and its day-to-day activities: identity formation and local economic life. Given the fact that drinking traditional alcohol in Africa is an intrinsic part of social life, it becomes an object in the articulation of diversity, coexistence, and preservation of identity. The study presents women as nodes thr