Search results

Filter

Filetype

Your search for "*" yielded 527090 hits

Being Nassau : Nassau family histories and Dutch national discourse from 1541 to 1616

William I of Nassau, Prince of Orange, and his sons Maurice and Frederick Henry were seen in their own time as the protectors of the new Dutch nation. As such, they play a significant role in the formation of a Dutch national identity. This essay addresses the question in what measure this sentiment was returned: did the Nassaus feel Dutch? An analysis of dynastic arguments used in the Apology (15

Altered asparagine and glutamate homeostasis precede coronary artery disease and type 2 diabetes

Context: Type 2 diabetes mellitus (T2DM) is accompanied by an increased risk for coronary artery disease (CAD), but the overlapping metabolic disturbances preceding both diseases are insufficiently described. Objective:Wehypothesized that alterations in metabolism occur years before clinical manifestation of T2DM and CAD and that these alterations are reflected in the plasma metabolome. We thus ai

Variation, companionship and manageability important for recovery during working hours : A qualitative focus group study

Lack of recovery from everyday strains and demands is connected to increased levels of stress-related problems and development of ill-health. There is much research on how to handle and prevent fatigue and stress in leisure time, but research on working time is more scarce. A recent study found that employees' experience of recovery during working hours was related to high self-rated health. OBJEC

Implementing a salutogenic treatment model in a clinical setting of emergency child and adolescent psychiatry in Sweden

Problem: Emergency care in child and adolescent psychiatry often lacks a coherent treatment model. This study reports on the development and implementation of a salutogenic treatment model at the Child & Adolescent Psychiatric Emergency Unit in Malmö, Sweden. Methods: The development and implementation involved all staff categories and was guided by a recognized authority on salutogenesis. Gen

Oral contraceptives and breast cancer : A review

Case-control and cohort studies published between 1977 and 1988 were reviewed with the purpose to evaluate the relationship between use of oral contraceptives (OC-use) and breast cancer risk, tumour biology and tumour prognosis with special emphasis on early OC-use. the risk of breast cancer was assessed in 30 case-referent studies and 5 cohort studies, and the prognosis of breast cancer had been

Relation between occupational exposure to organic solvents and chromosome aberrations in non‐Hodgkin's lymphoma

Chromosome analysis of lymphoma cells was performed in 54 untreated patients with non‐Hodgkin's lymphoma (NHL). 10 patients had a history of daily occupational handling of organic solvents for at least 1 year (exposed group) and 44 patients had never (or only for shorter periods) worked with solvents (unexposed group). There were no differences between exposed and unexposed patients regarding age,

Early oral contraceptive use and breast cancer among premenopausal women : Final report from a study in Southern Sweden

In southern Sweden during the 1960s, women began to use oral contraceptives (OCs) extensively at a young age. This case-control study investigates the relationship between the use of OCs and breast cancer development in women in southern Sweden diagnosed in the early 1980s. The risk for breast cancer after OC use among premenopausal women was modeled, after adjustment was made for age, age at mena

Islamic Modernities in Southeast Asia. Exploring Indonesian Popular and Visual Culture, by Leonie Schmidt

In Islamic Modernities in Southeast Asia, Leonie Schmidt provides a thorough analysis of contemporary Islamic-themed popular and visual cultures, mainly in Indonesia. This book is an essential read for those who wish to understand multiple modernities unfolding in post-1998 Indonesia (the Reformasi era). By using the term Islamic, she refers to any ‘cultural practices that are considered bernafask

An engineered combinatorial module of transcription factors boosts production of monoterpenoid indole alkaloids in Catharanthus roseus

To fend off microbial pathogens and herbivores, plants have evolved a wide range of defense strategies such as physical barriers, or the production of anti-digestive proteins or bioactive specialized metabolites. Accumulation of the latter compounds is often regulated by transcriptional activation of the biosynthesis pathway genes by the phytohormone jasmonate-isoleucine. Here, we used our recentl

Operation and performance of the ATLAS Tile Calorimeter in Run 1

The Tile Calorimeter is the hadron calorimeter covering the central region of the ATLAS experiment at the Large Hadron Collider. Approximately 10,000 photomultipliers collect light from scintillating tiles acting as the active material sandwiched between slabs of steel absorber. This paper gives an overview of the calorimeter’s performance during the years 2008–2012 using cosmic-ray muon events an

Heat release and flame spread assessment of insulation in External Thermal Insulation Composite System (ETICS) facades

External Thermal Insulation Composite Systems (ETICS) represent a popular modern facade for reducing energy consumption, particularly in retrofit applications. Insulation - typically in the form of either EPS (expanded polystyrene) or mineral wool - is applied to the exterior of buildings using mortar adhesive, and then coated with a final layer of sand-cement render and glass fibre reinforcement.

HER-2/neu and INT2 proto-oncogene amplification in malignant breast tumors in relation to reproductive factors and exposure to exogenous hormones

In previous studies in southern Sweden, early use of oral contraceptives has been found to be accompanied by an increased risk of developing premenopausal breast cancer, and the tumors developing in these patients have shown a more aggressive behavior. In the present study, amplification of the proto-oncogenes Her-2/neu (also known as ERBB2) and INT2 was studied in primary tumor specimens from 72

Survival in breast cancer and age at start of oral contraceptive usage

In general, findings in studies on oral contraceptives (OCs) and breast cancer have not indicated prognosis to be worse among users of OCs. In few studies, however, has age at the start of OC usage been considered as a prognostic factor. In the present study prognosis in breast cancer is compared with OC usage particularly with age at the start of OC usage among 193 consecutive patients at the Dep

The Analgesic Effect of Oxygen in Suspected Acute Myocardial Infarction : A Substudy of the DETO2X-AMI Trial

Objectives: In this substudy of the DETO2X-AMI (An Efficacy and Outcome Study of Supplemental Oxygen Treatment in Patients With Suspected Myocardial Infarction) trial, the authors aimed to assess the analgesic effect of moderate-flow oxygen supplementation in patients with suspected acute myocardial infarction (AMI) treated with percutaneous coronary intervention (PCI) and to study the effect of o

The molecular clutch model for mechanotransduction evolves

Many biological processes are influenced by the mechanical rigidity of surrounding tissues. Now, a combination of experiments and mathematical modelling has been used to describe the precise molecular and physical mechanism by which cells sense and respond to the mechanical properties of their extracellular environment through integrin-based adhesions.

A multicenter evaluation of the safety and effectiveness of a 0h/1h protocol in the assessment of emergency department chest pain patients.

BackgroundIn emergency department (ED) chest pain patients, the European Society of Cardiology recommends the use of a 0h/1h high-sensitivity cardiac Troponin (hs-cTn) protocol. However, the recommendation is based on observational studies and the effects of the protocol when implemented in routine care is unknown. The aim of this study is to determine the safety and effectiveness of the ESC 0h/1h

Proposal of highly accurate tests of Breit and QED effects in the ground state 2p5 of the F-like isoelectronic sequence

We propose that the ground term transition, 2p5P3/22-P1/22, for ions in the F-like isoelectronic sequence could be used to accurately test current methods to compute Breit and quantum-electrodynamic (QED) effects. These systems are of interest since correlation is small due to what we will label Layzer quenching. Using the multiconfiguration Dirac-Hartee-Fock method, we investigate how correlation