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The pre-fysch and basal shaly flysch deposition in the Parnassus-Ghiona Zone, central Greece

The interruption in deposition during the K/T transition in the Parnassus-Ghiona Zone caused the formation of hardgrounds and intraformational conglomerates in the central parts. During the later part of the early Paleocene to the middle or early part of the late Paleocene a shallow sea covered central Parnassus; stromatolites formed in broad valleys and phosphatic calcarenitic accumulations in sm

Failure of the vapor-liquid-solid mechanism in Au-assisted MOVPE growth of InAs nanowires

We report the temperature dependence of the Au-assisted growth of InAs nanowires in MOVPE. Extensive studies of the growth of such nanowires have attributed growth to the so-called vapor-liquid-solid (VLS) mechanism, with a liquid Au-In alloy particle. We assert here that growth is instead assisted by a solid particle and does not occur at all when the particle is a liquid. Thus the temperature ra

Effect of hypoxia on the tumor phenotype: the neuroblastoma and breast cancer models

The tumor oxygenation status associates with aggressive behavior. Oxygen shortage, hypoxia, is a major driving force behind tumor vascularization, and hypoxia enhances mutational rate, metastatic spread, and resistance to radiation and chemotherapy. We recently discovered that hypoxia promotes dedifferentiation of neuroblastoma and breast carcinoma cells and development of stem cell-like features.

Towards an integrated ecology through mechanistic modelling of ecosystem structure and functioning

Popular Abstract in Swedish Traditionellt har olika aspekter av ett ekosystem studerats var för sig inom olika ekologiska discipliner såsom växtfysiologi, forskning om hur organismer interagerar med varandra och forskning om hur ekosystem som helhet beter sig. Denna avhandling innehåller exempel på att simulationsmodeller gör det möjligt att undersöka hur de olika processerna samverkar för att forPlant physiology, population dynamics and the structure and functioning of ecosystems are closely interrelated. However, these processes are often investigated independently within different subdisciplines of ecology. Mechanistic models of ecosystem structure and functioning combine representations of processes operating at a range of scales and levels of organisation, providing a tool for the des

Targeting proteins to secretory lysosomes of natural killer cells as a principle for immunoregulation.

Secretory lysosomes of natural killer (NK) cells combine storage, regulated secretion and lysosomal activity. We asked whether one could target exogenous proteins to the secretory lysosomes of NK-cells for final delivery into a tumor site upon degranulation. cDNAs for both soluble and transmembrane (tm) proteins were expressed in the human YT-Indy NK-cell line. Targeting of a soluble TNF receptor

The common identity of five glycosidases in human liver

An enzyme has been isolated from human liver by DEAE-cellulose chromatography and has been shown by competitive substrate inhibition to be capable of hydrolysing synthetic beta-D-galactosides, beta-D-glucosides, beta-D-fucosides, beta-D-xylosides, and alpha-L-arabinosides. Another form of alpha-L-arabinosidase activity elutes with the major beta-D-galactosidase component on DEAE-chromatography, bu

From major amputation to prosthetic outcome: A prospective study of 190 patients in a defined population that underwent major amputation

In this prospective study, the overall treatment and outcome of patients that underwent major lower limb amputation in a defined population is described. The study was performed over a five year period in the Health Care District of North-East Skåne, Sweden. Some 190 patients, permanent inhabitants of the Health Care District, underwent major lower limb amputation. Sixteen (16) of these patients h

Toxicity in Peridinium aciculiferum - an adaptive strategy to outcompete other winter phytoplankton?

Freshwater dinoflagellates may form dense blooms during winter in ice-covered lakes. Unlike their marine counterparts, freshwater dinoflagellates are rarely considered to be potential toxin producers. Here we tested whether the winter species Peridinium aciculiferum produces a toxin(s) and investigated the potential adaptive function of that toxin, i.e., predator defense or inhibition of competito

Coupling between lateral modes in a vertical resonant tunneling structure

We present experimental results and theoretical calculations of the vertical electron transport through a laterally constricted resonant tunneling transistor. Current-voltage measurements at 4.2 K show numerous current peaks that exhibit a complex dependence on the applied gate voltage. A scattering-matrix approach combined with the Landauer formalism was used to perform quantum mechanical calcula

Experimental analysis of local flame extinction in a turbulent jet diffusion flame by high repetition 2-D laser techniques and multi-scalar measurements

In this paper, we present a detailed experimental study of turbulence chemistry interactions in the "DLR_B" turbulent jet diffusion flame. The flame operates on mixtures of CH4, H-2, and N-2 in the fuel stream at Re = 22,800 and is a target flame within the TNF workshop. Extinction and re-ignition events can be tracked in real time and related to the underlying flow field phenomena and temperature

Cell survival and clinical outcome following intrastriatal transplantation in Parkinson disease

Intrastriatal transplantation of embryonic dopaminergic neurons is currently explored as a restorative cell therapy for Parkinson disease (PD). Clinical results have varied, probably due to differences in transplantation methodology and patient selection. In this review, we assess clinical trials and autopsy findings in grafted PD patients and suggest that a minimum number of surviving dopaminergi

Om ojämlikhetens negativa värde – några anmärkningar

"Tidskrift för politisk filosofi" nr 2/2003 innehåller en kritisk granskning av Larry Temkins inflytelserika bok "Inequality" från 1993. Författarna, Ragnar Francén, Jonas Gren och Niklas Juth, underkastar Temkins komplexa, flerdimensionella form av egalitarism en noggrann undersökning. Deras kritiska synpunkter är väl värda läsarens uppmärksamhet.

Deglutition after near-fatal choking episode: radiologic evaluation

Acute airway obstruction during oral intake is a relatively common event that may be fetal if not relieved immediately. Deglutition was studied in 75 individuals who had experienced a near-fatal choking episode (NFCE) or sudden inability to breathe during food intake that was promptly relieved by means of a Heimlich maneuver, suctioning, or intubation. Videofluoroscopy supplemented by static imagi

Growth of GaP nanotree structures by sequential seeding of 1D nanowires

Complex nanostructures are becoming increasingly important for the development of nanoscale devices and functional nanomaterials. Precise control of size and morphology of these structures is critical to their fabrication and exploitation. We have developed a method for stepwise growth of tree-like nanostructures via the vapour liquid-solid (VLS) growth mode, demonstrated for III-V semiconductor m

Expression of platelet-derived growth factor-beta receptors on human fibroblasts. Regulation by recombinant platelet-derived growth factor-BB, IL-1, and tumor necrosis factor-alpha

Stimulation of human fibroblasts by platelet-derived growth factor (PDGF)-BB leads to a down-regulation of PDGF beta-receptors and a concomitant appearance of intracellular granular accumulations of receptors, as determined by stainings with the mAb PDGFR-B2. The granules contained both the ligand and PDGF beta-receptors, as revealed by double-immunofluorescence staining, and were formed in respon

Dietary fibre in fermented oat and barley beta-glucan rich concentrates

The ability of different lactic acid bacteria to influence the physicochemical characteristics (content, viscosity and molecular weight) of dietary fibre in beta-glucan-rich barley and oat concentrates was investigated. The cultures used were Lactobacillus acidophilus and the exopolysaccharide producing strain Pediococcus damnosus 2.6, together with the yoghurt culture, V2 (a mixture (1:1) of Lact

Humeral Head Resurfacing in the Rheumatoid Shoulder

Summary: The rheumatoid shoulder and elbow should be assessed in an early stage concerning the possibility of surgical intervention. The cause of the shoulder pain can be localized elsewhere in the shoulder girdle or in the neck. In patients with glenohumeral pain, resurfacing of the humeral head with a cup seems to be a good alternative to conventional stemmed prostheses. It diminishes the risk o