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Correlating the Bethesda System for Reporting Thyroid Cytopathology with Histology and Extent of Surgery : A Review of 21,746 Patients from Four Endocrine Surgery Registries Across Two Continents
Background: The Bethesda system for cytopathology (TBSRTC) is a 6-tier diagnostic framework developed to standardize thyroid cytopathology reporting. The aim of this study was to determine the risk of malignancy (ROM) for each Bethesda category. Methods: Thyroidectomy-related data from 314 facilities in 22 countries were entered into the following outcome registries: CESQIP (North America), Eurocr
Reduced Expression of PLCXD3 Associates With Disruption of Glucose Sensing and Insulin Signaling in Pancreatic β-Cells
Previous work has shown that reduced expression of PLCXD3, a member of the phosphoinositide-specific phospholipases (PI-PLC) family, impaired insulin secretion with an unclear mechanism. In the current study, we aim to investigate the mechanism underlying this effect using human islets and rat INS-1 (832/13) cells. Microarray and RNA sequencing data showed that PLCXD3 is among the highly expressed
Effect of excess charge carriers and fluid medium on the magnitude and sign of the Casimir-Lifshitz torque
Last year, we reported a perturbative theory of the Casimir-Lifshitz torque between planar biaxially anisotropic materials in the retarded limit [Thiyam et al., Phys. Rev. Lett. 120, 131601 (201810.1103/PhysRevLett.120.131601)], which is applied here to study the change in sign and magnitude of the torque with separation distance in biaxial black phosphorus having excess charge carriers. The study
A nutrient-wide association study for risk of prostate cancer in the European Prospective Investigation into Cancer and Nutrition and the Netherlands Cohort Study
Purpose: The evidence from the literature regarding the association of dietary factors and risk of prostate cancer is inconclusive. Methods: A nutrient-wide association study was conducted to systematically and comprehensively evaluate the associations between 92 foods or nutrients and risk of prostate cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC). Cox proportio
The chemokine CXCL16 is a new biomarker for lymph node analysis of colon cancer outcome
Chemokines are important in the development and progression of tumors. We investigated the expression of CXCL14 and CXCL16 in colon cancer. Expression of mRNA was assessed in primary tumors and lymph nodes and CXCL16 mRNA levels were correlated to patient’s survival. Protein expression was investigated by two-color immunofluorescence and immunomorphometry. CXCL14 and CXCL16 mRNA levels and protein
Increased genetic marker density reveals high levels of admixture between red deer and introduced Japanese sika in Kintyre, Scotland
Hybridization is a natural process at species range boundaries, but increasing numbers of species are hybridizing due to direct or indirect human activities. In such cases of anthropogenic hybridization, subsequent introgression can threaten the survival of native species. To date, many such systems have been studied with too few genetic markers to assess the level of threat resulting from advance
A broadside three-port antenna for 5G massive MIMO antenna systems
This paper presents a broadside antenna with three ports operating at the same frequency. The TM030 and TM003 modes of a patch are excited by two coaxial cables to generate two orthogonal linear polarizations. The patch can be transformed into a slotted SIW cavity whose TE201 and TE102 modes are jointly excited by the third cable. A matching cavity and a matching patch are introduced to broaden th
Self-rated health and venous thromboembolism among middle-aged women : a population-based cohort study
Venous thromboembolism (VTE) is one of the most common types of cardiovascular diseases (CVDs) and is associated with increased mortality-risk. Poor-self rated health (SHR) has been associated with elevated inflammatory markers and CVDs. However, little is known about as a predictor of incident VTE. To examine the association between self-rated health, lifestyle and incident VTE among middle-aged
Tax Incentives for Charities in the European Union: Integration or Segregation?
Because of their important role in civil society, charities are often granted a special status in national tax legislation. Many charities initiate activities abroad and come in the realm of EU law, for example, because of cross border investments, fundraising activities and competition with foreign charities. Tax legislation for charities is, however, not harmonized in the EU and varies widely. E
Chemical Heterogeneity of Mg, Mn, Na, S, and Sr in Benthic Foraminiferal Calcite
The chemical composition of fossil foraminiferal shells (tests) is widely used as tracers for past ocean chemistry. It is, therefore, important to understand how different (trace) elements are transported and incorporated into these tests from adjacent seawater. The elemental distribution within the walls of foraminiferal tests might be used to differentiate between proposed transport mechanisms.
Floating Thermal Piles in Soft Sensitive Clays
Thermal piles are building foundation piles which, in addition to transferring the load of the building to the ground, are also used as heat exchangers to provide thermal exchange with the ground. This article shortly presents field testing of thermal piles installed in soft sensitive clay in Gothenburg. The aim of the field tests is to study the thermo-mechanical response of the heating and cooli
Bullying and Pain in School-Aged Children and Adolescents : A Cross-Sectional Study
Bullying is defined as repeated and unwanted aggressive behavior involving a power imbalance and hurt children and adolescents’ socioemotional functioning. The aim is to investigate associations between pain (headache, stomach pain, backache, and neck/shoulder pain) and bullying among school-aged children and adolescents. This cross-sectional school-based survey comes from the Icelandic data set i
Recension av Ibrahim Alsabagh: Letters from Aleppo: Chronicles of War and Hope och Ziad Hilal & François-Xavier Maigre: Homs, l’éspérance obstinée.
Recension av två böcker om katolska präster i inbördeskrigets Syrien.
The impact of endurance training and table soccer on brain metabolites in schizophrenia
Higher glutamate and glutamine (together: Glx) and lower N-acetyl-aspartate (NAA) levels were reported in schizophrenia. Endurance training normalizes NAA in the hippocampus, but its effects on other metabolites in the brain and the relationship of metabolites to clinical symptoms remain unknown. For 12 weeks, 20 schizophrenia inpatients (14 men, 6 women) and 23 healthy controls (16 men, 7 women)
Knockout of the non-essential gene SUGCT creates diet-linked, age-related microbiome disbalance with a diabetes-like metabolic syndrome phenotype
SUGCT (C7orf10) is a mitochondrial enzyme that synthesizes glutaryl-CoA from glutarate in tryptophan and lysine catabolism, but it has not been studied in vivo. Although mutations in Sugct lead to Glutaric Aciduria Type 3 disease in humans, patients remain largely asymptomatic despite high levels of glutarate in the urine. To study the disease mechanism, we generated SugctKO mice and uncovered imb
Analysis of the LIF/Mie ratio from individual droplets for planar droplet sizing : Application to gasoline fuels and their mixtures with ethanol
In this work, the possibility of using planar droplet sizing (PDS) based on laser-induced fluorescence (LIF) and Mie scattering was investigated within the framework of measuring the droplet Sauter mean diameter (SMD) of direct-injection spark-ignition (DISI) spray systems. For this purpose, LIF and Mie signals of monodisperse fuel droplets produced by a droplet generator were studied at engine re
In conversation with Elizabeth Minnich
At the conference of the International Society for the Scholarship of Teaching and Learning (ISSOTL) in Bergen, Norway (October 2018), we were privileged to have heard a lecture by Elizabeth Minnich, “People who are not thinking are capable of anything: What are students learning, how are students learning it, and does it make them better people?”In November 2018, as a follow-up to the lecture, Ch
Decentralized equalizer construction for large intelligent surfaces
In this paper we present fully decentralized methods for calculating an approximate zero- forzing (ZF) equalizer in a large intelligent surface (LIS). A LIS is intended for wireless communication and facilitates unprecedented MU- MIMO performance, far superior to that of Massive MIMO. Antenna modules in the grid connect to their neighbors to exchange messages of information needed for interference
Preliminary study on differences between full-and sub-structure characteristic modes
In this paper, full-and sub-structure characteristic modes (CMs) are explored through the effect of coupling between the target and background structures. The eigenvalues and eigen-current distributions of the first few modes are compared for different coupling levels in the numerical example. Similarities and differences between the two types of CMs in specific conditions are revealed, paving the