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Introduction : Candidates between parties and voters-A triadic relationship in the belgian partitocracy

The introductory chapter emphasises the general relevance of the study of electoral candidates in representative democracies. It presents the book’s theoretical framework: the triadic delegation and accountability relationship between candidates, voters and parties—based on principal–agent theory. We theoretically map patterns of candidates’ behaviour and attitudes in all main dimensions of their

Conclusion : Studying candidates, parties and voters. Lessons learned and new questions

In the concluding chapter, we outline the major findings from the eleven book chapters by connecting them to one another. We come back to the triadic delegation and accountability relationship between candidates, voters and parties that were developed based on principal–agent theory, and emphasise the most relevant findings of this book that inform this triad. The chapter also takes a critical sta

Reconstructing cold climate paleoenvironments from micromorphological analysis of relict slope deposits (Serra da Estrela, Central Portugal)

The paper focuses on analysis of macro‐ and micromorphological characteristics of relict slope deposits in Serra da Estrela (Portugal) to understand the significance of different slope processes and paleoenvironmental settings. Micromorphology is a useful sedimentology technique allowing significant advances compared to macroscopic techniques. Results show that different processes are involved in

Is there an ‘iron law’ of Big Science?

Big Science is costly and complex, and historical evidence seems to suggest that projects often get delayed and more expensive than planned. On the basis of several studies of large infrastructures such as railroads and bridges, the Danish geographer Bent Flyvbjerg has proposed that there is an “iron law” of megaprojects, meaning that they almost without exception turn out more expensive and more

Big Science and Research Infrastructures in Europe

This thought-provoking book expands on the notion that Big Science is not the only term to describe and investigate particularly large research projects, scientific collaborations and facilities. It investigates the significant overlap between Big Science and Research Infrastructures (RIs) in a European context since the early twenty-first century. Contributions to this innovative book not only au

Daily Adaptive Proton Therapy : Is it Appropriate to Use Analytical Dose Calculations for Plan Adaption?

Purpose: The accuracy of analytical dose calculations (ADC) and dose uncertainties resulting from anatomical changes are both limiting factors in proton therapy. For the latter, rapid plan adaption is necessary; for the former, Monte Carlo (MC) approaches are increasingly recommended. These, however, are inherently slower than analytical approaches, potentially limiting the ability to rapidly adap

Outcome and determinants of failure to complete primary R-CHOP treatment for reasons other than non-response among patients with diffuse large B-cell lymphoma

Patients with diffuse large B-cell lymphoma (DLBCL) who fail to complete planned treatment with R-CHOP due to toxicity are sparsely described. We investigated the extent of failure to complete treatment (six cycles or more, or three cycles + RT for patients with stage I disease) with R-CHOP for reasons unrelated to non-response, the determinants of such failure and the outcome among these patients

Comparing Self-Reported Sugar Intake With the Sucrose and Fructose Biomarker From Overnight Urine Samples in Relation to Cardiometabolic Risk Factors

Studies on sugar intake and its link to cardiometabolic risk show inconsistent results, partly due to dietary misreporting. Cost-effective and easily measured nutritional biomarkers that can complement dietary data are warranted. Measurement of 24-h urinary sugars is a biomarker of sugar intake, but there are knowledge gaps regarding the use of overnight urine samples. We aim to compare (1) overni