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Numerical Methods for Conceptual Structural Design

Conceptual design is the first phase in the design process in which all the requirements and design objectives are synthesized into conceptual alternatives. In practice today, major decisions regarding the buildings geometry, massing, and overall form are usually made during the first phase. Considering structural performance requirements during conceptual design enhances interdisciplinary interac

Acting on distances: A topology of accounting inscriptions

Following on the reiterated claim that accounting inscriptions make action at a distance possible, we draw on post-mathematical topology to explain that this distance work is dependent on inscriptions acting on distances. By adopting a relational understanding of space, we show that accounting inscriptions by themselves create the distances across which they operate. Our case study uses pay-as-you

Predictive and prognostic clinical variables in cancer patients treated with adenoviral oncolytic immunotherapy

The development of oncolytic viruses has recently made great progress towards being available to cancer patients. With the breakthrough into clinics, it is crucial to analyze the existing clinical experience and use it as a basis for treatment improvements. Here we report clinical data from 290 patients treated with oncolytic adenovirus. Using clinical variables and treatment characteristics, we c

Metamorphism and Geochronology of the High Pressure Granulite and Upper Amphibolite Facies Rocks from the Southwest Swedish Granulite Region

The present thesis presents pressure-temperature and geochronological data from the high-grade mafic rocks from the Southwest Swedish Granulite Region, which forms part of the southwestern Baltic Shield. The region is characterized by variably deformed and migmatized granitic to intermediate gneisses, metabasites and charnockites metamorphosed in granulite and upper amphibolite facies. The peak m

A 103fsrms 1.32mW 50MS/s 1.25MHz Bandwidth Two-Step Flash-ΔΣ Time-to-Digital Converter for ADPLL

A 50-MS/s two-step flash-ΔΣ time-to-digital converter (TDC) using a 2-channel time-interleaved time-domain register with an implicit adder/subtractor demonstrates a 3rd order noise-shaping. The TDC is fabricated in 40-nm CMOS and consumes 1.2 mA from a 1.1 V supply. At frequencies below 1.25 MHz, the TDC error integrates to 103 fsrms, which is equal to an equivalent resolution of 1.6 ps.

Energy services and development

Increased energy efficiency at the point of end-use is a key strategy for addressing a range of energy related problems, including greenhouse gas emissions. There are energy efficiency alternatives that can be implemented at low cost,and perhaps with some cost savings – these activities offer no-regrets opportunities for climate change mitigation. In addition, high levels of end-use energy efficie