Squamous-cell carcinoma of the anus (ASCC) is a rare disease. Barriers have been encountered to conduct clinical and translational research in this setting. Despite this, ASCC has been a prime example of collaboration amongst researchers. We performed a bibliometric analysis of ASCC-related literature of the last 20 years, exploring common patterns in research, tracking collaboration and identifyi

Towards the close of the nineteenth century and into the twentieth century, there was a proliferation of Christian missionaries in Africa. Upon settling in Africa, missionaries initiated and became the main providers of Western-styled education and health care. For this reason, the historical and enduring impact of missionaries in Africa cannot be overlooked. This thesis examines the synchronic an

This chapter focuses on the oxidative stability of n-3 polyunsaturated fatty acids (n-3 PUFAs) delivery systems and n-3 PUFAs fortified foods during digestion, with specific attention given to the long-chain n-3 PUFAs. The topic is of importance since the formation of reactive lipid oxidation products in the gastrointestinal tract (GIT) can lead to unwanted reactions e.g., with proteins, phospholi

Dopamine replacement therapy with L-DOPA is the most efficacious symptomatic treatment for Parkinson's disease, but its utility is limited by a development of motor fluctuations and abnormal involuntary movements (dyskinesia) in the majority of patients. These complications are attributed to the combined effects of dopaminergic degeneration and non-physiological reinstatement of dopamine transmiss

AimOur aim is to provide a-priori information on air-quality implications of potential future energy carriers in transportation relevant for sustainability, life cycle and health-impact assessments.MethodologyInformation on air- and climate-pollutant formation from energy carriers is collected in detailed laboratory assessments on heavy-duty combustion engines as well as on non-tailpipe emissions.

Humanitarian organisations are central actors in the mediation of humanitarian disasters as objects of public, political and moral concern. Consequently, if we want to understand this key dynamic of world politics we have to understand how aid organisations use media. But whereas extant knowledge about media and global humanitarianism focuses primarily on issues related to discourses and images of

A detailed investigation of ion channelling and defect production for a highly- ordered array of multi-wall carbon nanotubes is presented. The effects of argon ion bombardment (0.25–5 keV) carried out either parallel (top) or perpendicular (side) to their axis, have been studied by Raman, X-Ray Photoelectron Spectroscopy and Scanning Electron Microscopy. Raman spectra provided evidence of channell

It is important to obtain accurate three dimensional structures of molecules and proteins to understand and predict their function and behaviour. X-ray crystallography is the major technique to determine three dimensional structures of proteins. Although there have been major improvements on the experimental side in determining crystallographic data, only small progress has been made on the comput

This thesis maps the different geographical processes by which people in Enlightenment Edinburgh encountered, understood and ordered space. It analyses the knowledge-making practices that were an integral part of Enlightenment reasoning, and that contributed to the construction of Edinburgh’s identity as an Enlightenment capital. In particular, it focuses on four aspects of mapping: planning, surv

Low-temperature cathodo- and photoluminescence connected with the F and F+ centers (oxygen vacancies in different charge states) and bivacancies have been investigated in MgO single crystals preliminarily irradiated by 230-MeV 132Xe ions with varying fluence (up to 1014 ions/cm2). The cathodoluminesence bands (result of decomposition into Gaussians) related to the F, F+ and P centers have intensif

Background & aims: Tea has been shown to be associated with reduced risk of several diseases including cardiovascular diseases, stroke, metabolic syndrome, and obesity. However, the results on the relationship between tea consumption and bladder cancer are conflicting. This research aimed to assess the association between tea consumption and risk of bladder cancer using a pooled analysis of pr

Med fokus på digitala lärplattformar ställer denna studie frågan: vad är egentligen viktigast för studenterna i den digitala lärmiljön? Vad är den vanligaste anledningen till att studenter upplever att de digitala verktygen ställer till det för dem? Resultatet visar att det finns ett par faktorer som gäller struktur och förståelse av lärarens tanke med kursen som behöver vara uppfyllda för att kur