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SPIRE—a software tool for bicontinuous phase recognition : application for plastid cubic membranes

Bicontinuous membranes in cell organelles epitomize nature’s ability to create complex functional nanostructures. Like their synthetic counterparts, these membranes are characterized by continuous membrane sheets draped onto topologically complex saddle-shaped surfaces with a periodic network-like structure. Their structure sizes, (around 50–500 nm), and fluid nature make transmission electron mic

Frailty and osteoporosis in patients with hip fractures under the age of 60-a prospective cohort of 218 individuals

Research on younger patients with hip fractures is limited. This study adds knowledge on patient and injury characteristics, and DXA was investigated at the time of the fracture. Risk factors for osteoporosis and fractures were numerous among young patients, and osteoporosis was markedly more prevalent than in the general population.INTRODUCTION: Knowledge on younger patients with hip fractures is

Overexpressed beta cell CART increases insulin secretion in mouse models of insulin resistance and diabetes

Impaired beta cell function and beta cell death are key features of type 2 diabetes (T2D). Cocaine- and amphetamine-regulated transcript (CART) is necessary for normal islet function in mice. CART increases glucose-stimulated insulin secretion in vivo in mice and in vitro in human islets and CART protects beta cells against glucotoxicity-induced cell death in vitro in rats. Furthermore, beta cell

Lessons of History: An Impossible Equation? : Towards New Perspectives on Historical Learning

Lessons of history are two-sided cultural products. They serve as active instruments of temporal orientation in a society in which historical trajectories seem obsolete and the future open, but they are also passively framed within historical cultures that often have prefigured them. Thus, lessons are seldom arbitrarily constructed. while lessons of history for many centuries were highly esteemed

Cystatin C-based equations for estimating glomerular filtration rate do not require race or sex coefficients.

Estimation or measurement of glomerular filtration rate (GFR) is generally required for optimal treatment of patients. Plasma creatinine has been used for estimation of GFR since 1926 and plasma cystatin C since 1979. The creatinine level is strongly dependent upon muscle mass and as the average muscle mass of dif- ferent populations may vary, creatinine-based GFR-estimating equations have since 1

Penetration Depth and Coherence Length in the Superconductor β-PdBi2

Small angle neutron scattering experiments have been carried out in the mixed state to determine the values and anisotropy of the penetration depth and coherence length in the superconductor β-PdBi2. The distortion of the vortex lattice observed on changing the magnetic field direction suggests that the a–c anisotropy of penetration depth in β-PdBi2 is small. With the magnetic field applied along

Understanding client satisfaction in elderly care: new insights from social resource theory

Social resource theory suggests that social interaction can be conceived as resource transaction or exchange with behaviours falling within six fundamental resource categories (i.e. love, status, information, money, goods, and services) organised along two underlying dimensions: particularism–universalism and concreteness–abstractness. With the purpose of extending knowledge about quality of care,

Att bedriva sociologisk forskning i en tid av byråkratiserad etikprövning

Sverige är ett få länder i världen som reglerar forskningsetik i lag. Men vad händer när en enhetlig lagstiftning inte har hänsyn till olika forskningsdiscipliners särart, och forskningsetiken formaliseras i ämnesövergripande förordningar? Den formella process som etikprövning av forskning har utvecklats till kan innebära en utmaning för möjligheten att bedriva sociologisk forskning, både vad gäll

START-TO-END STUDY ON LASER AND RF JITTER EFFECTS FOR MAX IV SXL

A Soft X-ray free electron laser (FEL) for the MAX IV Laboratory is currently in the design phase and it will use the existing 3 GeV linac. Present stability limits in the RF and the photocathode laser will affect the performance of the FEL. One of the critical elements for the design of a FEL is to have an estimation on jitter effects of the accelerator parameters on the X-ray radiation. In this

The development of musculoskeletal radiology for 100 years as presented in the pages of Acta Radiologica

During the last 100 years, musculoskeletal radiology has developed from bone-only radiography performed by everyone to a dedicated subspecialty, still secure in its origins in radiography but having expanded into all modalities of imaging. Like other subspecialties in radiology, it has become heavily dependent on cross-sectional and functional imaging, and musculoskeletal interventions play an imp

Role of HAMLET and metabolism in treatment and pathogenesis of pneumococci

Antimicrobial resistance (AMR) is one of the principle public health problems in the 21st century, threatening the available treatment strategies for bacterial infections. Here, we present a human protein-lipid complex, HAMLET (human alpha-lactalbumin made lethal to tumor cells) purified from human milk as a potential therapeutic agent which has both tumoricidal and bactericidal activity. HAMLET’s

Social Value of the Child

This pictorial presentation of childhood aims to provide a visual depiction of the social value of the children in rural Punjabi socio-cultural context. I took these photographs in a village in south Punjab, Pakistan while doing an ethnographic inquiry about infant healthcare belief practices and the social value of the child in rural Punjab.

Is tourist walkability and well-being different?

Despite the environmental and health importance of tourist walking, specific research on walking and tourism is limited, with walking in leisure and work contexts often being used as a proxy. To fill this gap, this study identifies the effects of perception of air quality and mitigating climate change on attachment to walking relevant to walkable places and subjective well-being, along with compar

Categorisations Impeding and Supporting Universal Design

*Introduction* The adoption of Universal Design in European countries introduces a demand for and ex-pectations of a culture which supports equality and non-stigmatisation, treasuring diversi-ty and striving towards a society for all. *Background*Universal Design comes with a set of values, which create tensions between established practices based on “persons with disabilities” as a distinct, sepa*Introduction* The adoption of Universal Design in European countries introduces a demand for and ex-pectations of a culture which supports equality and non-stigmatisation, treasuring diversi-ty and striving towards a society for all. *Background*Universal Design comes with a set of values, which create tensions between established practices based on “persons with disabilities” as a distinct, sepa

The dis/ablement of bodies in semiotic landscapes – a citizen science approach

Much of our built environment is constructed to accommodate ‘normate’ (Garland-Thomson 1996; Hamraie 2017) bodies. This fact may remain invisible to normate users of public space, much as the ordering of human interaction through categorisation is often invisible (Bowker & Star 1999). Reading semiotic landscapes through the dis/abling (Campbell 1999) of bodies that (attempt to) move through thMuch of our built environment is constructed to accommodate ‘normate’ (Garland-Thomson 1996; Hamraie 2017) bodies. This fact may remain invisible to normate users of public space, much as the ordering of human interaction through categorisation is often invisible (Bowker & Star 1999). Reading semiotic landscapes through the dis/abling (Campbell 1999) of bodies that (attempt to) move through th

Initial Analysis of Dynamic Panel Activation for Large Intelligent Surfaces

Large intelligent surfaces (LIS) have the potential to be the beyond-massive-MIMO solution, even further improving spectral efficiency, coverage, reliability and other performance measures. They also open up for entirely new services, such as precise localization, environment sensing, and wireless energy transfer. By constructing larger surfaces as a grid of panels, we can activate and deactivate