Successful innovation strategy relies on experience gained from a complexity of understanding, anticipating and managing the global business environment. But, although much research has examined strategies of private sector organizations in Western economies, there are relatively few studies of innovation in public sector organizations of transitional and protected economic environments, such as I

Ischemic stroke triggers neurogenesis from neural stem/progenitor cells (NSPCs) in the subventricular zone (SVZ) and migration of newly formed neuroblasts towards the damaged striatum where they differentiate to mature neurons. Whether it is the injury per se or the associated inflammation that gives rise to this endogenous neurogenic response is unknown. Here we showed that inflammation without c

The traditional Furongian trilobite biozones of Scandinavia, recently proposed abandoned due to inconsistent boundary definitions [Terfelt, F., Eriksson, M.E., Ahlberg, P. & Babcock, L.E., 2008: Furongian Series (Cambrian) biostratigraphy of Scandinavia - a revision. Norwegian Journal of Geology88, 73-87], are resurrected and elevated to superzonal rank. These superzones are usually readily re

Simulations of carbon fluxes with terrestrial biosphere models still exhibit significant uncertainties, in part due to the uncertainty in model parameter values. With the advent of satellite measurements of solar induced chlorophyll fluorescence (SIF), there exists a novel pathway for constraining simulated carbon fluxes and parameter values. We investigate the utility of SIF in constraining gross

The continuously increasing solid waste generation worldwide calls for management strategies that integrate concerns for environmental sustainability. By quantifying environmental impacts of systems, life cycle assessment (LCA) is a tool, which can contribute to answer that call. But how, where and to which extent has it been applied to solid waste management systems (SWMSs) until now, and which l

We describe integrated strategies that employ both translation of ENCODE data and major proteomic technology pillars to improve the identification of the missing proteins, protein isoforms, and PTMs. The results from proteoENCODEdb searches with experimental mass spectral data indicate that some novel splice forms detected at the transcript level are in fact translated to proteins. Our results pro

Type III receptor tyrosine kinases (RTKs), FLT3 and c-Kit play important roles in a variety of cellular processes. A number of SH2-domain containing proteins interact with FLT3 and c-Kit and regulate downstream signaling. The SH2-domain containing non-receptor protein tyrosine kinase CSK is mainly studied in context of regulating Src family kinases. Here we present an addition role of this kinase

The European electric power industry has undergone considerable changes over the past two decades as a result of more stringent laws concerning environmental protection along with the deregulation and liberalization of the electric power market. However, the pressure to deliver solutions in regard to the issue of climate change has increased dramatically in the last few years and has given rise to

Objective: C-peptide is a main outcome measure in treatment trials of diabetes. C-peptide also has a role in the classification of diabetes, which is often difficult in adults and this is also increasingly recognised in adolescents and elders. Aim: We aimed to describe the levels of C-peptide in relation to age and body mass index (BMI) in a large population-based cohort of adults with newly diagn

Infantile colic is common, but no safe and effective conventional treatment exists. The use of acupuncture has increased despite weak evidence. This practitioner survey explores and discusses how infantile colic is regarded and treated in Traditional Chinese Medicine (TCM). The study is based on personal communication with 24 acupuncturists from nine countries. These acupuncturists specialize in p

The phylogenetic structure and community composition were analysed in an existing data set of marine bacterioplankton communities to elucidate the evolutionary and ecological processes dictating the assembly. The communities were sampled from coastal waters at nine locations distributed worldwide and were examined through the use of comprehensive clone libraries of 16S ribosomal RNA genes. The ana

In this study we aimed to evaluate effects of liver resection on hepatic microcirculation. In addition we wanted to study if histological liver damage could be detected intra-operatively.

In this paper, a new application of resonant acoustic spectroscopy (RAS) is examined for constructing asphalt concrete mastercurves from seismic testing. The frequency-dependent material properties can be characterized from multiple modes of vibration through the use of RAS. Beam-shaped asphalt specimens are tested at multiple temperatures to determine the resonance frequencies of the specimens. T

In 2007, the EU decided to cut greenhouse gas emissions by 20/30 per cent, something which was considered a proof of the EU's willingness to take on high targets independently of others. In the period 2009-11, the EU was debating but could not reach an agreement on stepping up to a 30 per cent reduction target. This raises the question: why did the EU go from being capable of adopting high targets

BACKGROUND: Multiple laboratory tests are used to diagnose and manage patients with diabetes mellitus. The quality of the scientific evidence supporting the use of these tests varies substantially. APPROACH: An expert committee compiled evidence-based recommendations for the use of laboratory testing for patients with diabetes. A new system was developed to grade the overall quality of the evidenc

The polyamines are important for a variety of cellular functions, including cell growth. Their intracellular concentrations are controlled by a complex network of regulatory mechanisms, in which antizyme (Az) has a key role. Az reduces the cellular polyamine content by down-regulating both the enzyme catalysing polyamine biosynthesis, ornithine decarboxylase (ODC), and the uptake of polyamines. Th

The aim of this study was to investigate if preoperative measurements of the femoral valgus angle (FVA) affected the mechanical alignment, individual component positions and clinical outcome in total knee arthroplasty (TKA).

Does perfluorooctane sulfonate (PFOS) and perfluorooctanate (PFOA) exposure disrupt the menstrual cyclicity? The female reproductive system may be sensitive to PFOA exposure, with longer menstrual cycle length at higher exposure. PFOS and PFOA are persistent man-made chemicals. Experimental animal studies suggest they are reproductive toxicants but epidemiological findings are inconsistent. A cros