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Urine excretion of protein HC in proteinuric glomerular diseases correlates to urine IgG but not to albuminuria

BACKGROUND: Proteinuric glomerular diseases often are associated with tubulointerstitial injury, which imposes on the progression of renal failure. Tubular damage is partly referable to toxic effects on the tubular epithelial cells induced by filtered plasma proteins. Patients with nonselective proteinuria, that is, increased urine excretion of high-molecular-weight plasma proteins such as IgG in

Relationships of plasma adiponectin level and adiponectin receptors 1 and 2 gene expression to insulin sensitivity and glucose and fat metabolism in monozygotic and dizygotic twins.

Context: Adiponectin is a key insulin-sensitizing adipokine acting on muscle metabolism via two specific receptors [adiponectin receptors 1 and 2 (AdipoR1 and AdipoR2, respectively)]. Objectives: The aim of the study was to investigate the genetic and nongenetic control of plasma adiponectin and muscle AdipoR1/R2 gene expression and the impact of these components on in vivo glucose and fat metabo

The role of the leukemia-associated ETO homologue repressors in hematopoiesis

Popular Abstract in Swedish Blodet fyller livsviktiga uppgifter i kroppen såsom syretransport och infektionsförsvar. De röda blodkropparna sköter syretransporten och de vita blodkropparna hanterar infektionsskyddet eller immunförsvaret. Blodplättar står för blodets levring vid blödning. Efterhand förbrukas blodcellerna och därför sker en kontinuerlig nybildning. Vid akut behov kan produktionen av The fusion protein AML1-ETO is observed in acute myeloid patients with the chromosomal translocation t(8;21). Cells with this chimeric protein have impaired granulocytic and erythroid differentiation with accumulation of myeloblasts. The transcriptional co-repressor ETO (Eight Twenty One) was identified from the cloning of AML1-ETO. Subsequently, MTGR1 (Myeloid Translocation Gene-Related protein 1

Patterns of normal change in cervical length and width during pregnancy in nulliparous women: a prospective, longitudinal ultrasound study

OBJECTIVES: To determine what constitutes normal changes in the uterine cervix visible at transvaginal ultrasound examination from 24 gestational weeks until delivery in nulliparous women delivering at term. DESIGN: Cervical length and width were measured using transvaginal ultrasound, and the inner cervical os was assessed as being closed or open every 2 weeks from gestational week 24 until deliv

District Heating for Residential Areas with Single-Family Housing -with Special Emphasis on Domestic Hot Water Comfort

Popular Abstract in Swedish Konceptet fjärrvärme inbegriper central värmeproduktion från vilken värme distribueras ut till de enskilda förbrukarna via ett rörsystem. Ett grundläggande krav, med hänsyn till fjärrvärmens konkurrenskraft, är att vinsten som görs i den storskaliga värmeproduktionen, jämfört med lokal värmeproduktion, överstiger kostnaderna för värmedistributionen. DistributionskostnadThe concept of district heating (DH) involves centralised heat production where heat is distributed to consumers via a piping network. It is essential that benefits achieved from concentrated, large-scale production instead of local production in each building exceed the costs associated with heat distribution. Since the distribution cost per delivered kWh increases as the heat density of an area

Phase transition to frequency entrainment in a long chain of pulse-coupled oscillators

A long chain of pulse-coupled oscillators was studied. The oscillators interacted via a phase response curve similar to those obtained from pacemaker cells in the heart. The natural frequencies were random numbers from a distribution with finite bandwidth. Stable frequency-entrained states were shown always to exist above a critical coupling strength. Below the critical coupling, the probability t

Passive smoking and childhood asthma. Urinary cotinine levels in children with asthma and in referents

Passive exposure to tobacco smoke was assessed in children with asthma (age 3-15) and in referents. There was statistically significantly (P less than 0.0005) higher excretion of the nicotine metabolite, cotinine, in the urine of 49 children with asthma (geometric mean 10 ng/ml) compared with 77 referents (4.8 ng/ml). Maternal smoking was statistically significantly more prevalent among the asthma

Driving forces of phase transitions in surfactant and lipid systems

In aqueous surfactant and lipid systems, different liquid crystalline phases are formed at different temperatures and water contents. The "natural" phase sequence implies that phases with higher curvature are formed at higher water contents. On the other hand, there are exceptions to this rule, such as the monoolein/water system. In this system an anomalous transition from lamellar to reverse cubi

Exploring Levers for Improvement of Basic Civil Aviation Training

Popular Abstract in Swedish Även om civil flygindustri har genomgått stora teknologiska och kommersiella förändringar under de senaste årtiondena så har grundläggande civil flygutbildning inte förändrats på motsvarande sätt. Förändringarna inom civilflyget har sällan resulterat i forskningsprogram med inriktning mot grundläggande flygutbildning och denna utbildningsfas har länge varit föremål för Although the civil aviation industry has gone through great technological and commercial change in the last decades, basic civil aviation training has not kept pace accordingly. The changes in civil aviation have rarely resulted in research programs in the field of basic training, which has long received minimal attention from the industry. In the research presented in this thesis, methods for und

High-spin States in the Tz = -1/2 Nucleus 55Ni

High-spin states of the isospin T-z = -1/2 nucleus Ni-55 have been identified for the first time by means of the reaction Si-28(Ar-36,2 alpha n) at 143 MeV beam energy. The GAMMASPHERE array together with ancillary detectors was used to detect gamma rays in coincidence with evaporated light particles. The level scheme of Ni-55 comprising four transitions is compared to its mirror partner Co-55 and

Sex ratio dynamics and fluctuating selection pressures in natural populations of the Trinidadian guppy, Poecilia reticulata

In many species, population sex ratios have far-reaching consequences for a wide variety of population-level and behavioural processes and can directly influence sexual selection through differential effects on male and female mating behaviour. Although sex ratios are often treated as more or less stable population characteristics, recent theoretical evidence suggests that sex ratios fluctuate und

Kinetics of ammonia decomposition in hot gas cleaning

Reduction in the amount of ammonia in fuel gas from biomass gasification was studied. Experiments were carried out in a fixed-bed reactor dt 200-1000 degrees C, 21 atm. A kinetic model for ammonia decomposition was developed. The partial pressure of hydrogen in the fuel gas was a key factor to model ammonia decomposition. Activation energies in the empty reactor, on carbon, and in a sand bed were

Levothyroxine treatment reduces thyroid size in children and adolescents with chronic autoimmune thyroiditis.

Context: The use of levothyroxine to reduce thyroid size in pediatric patients with goiter due to chronic autoimmune thyroiditis (AIT) remains controversial. In overtly hypothyroid patients, reductions in thyroid volume have been reported, whereas the effect in subclinically hypothyroid and euthyroid patients is less clear. Objective: The objective of the study was to evaluate the effect of levot

Vitamin k-dependent protein s localizing complement regulator c4b-binding protein to the surface of apoptotic cells.

Apoptosis is characterized by a lack of inflammatory reaction in surrounding tissues, suggesting local control of complement activation. During the initial stage of apoptosis, cells expose negatively charged phospholipid phosphatidylserine on their surfaces. The vitamin K-dependent protein S has a high affinity for this type of phospholipid. In human plasma, 60-70% of protein S circulates in compl