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Monolithic vs. polylithic design cultures? : Designers' accounts of professional practices in Sweden and New Zealand

This comparative study explores how breaches can be applied to unveil potential blindspots within the social constructs surrounding design practice in Sweden and New Zealand. When in-depth interviews with designers in both countries were analysed, similarities and differences appeared. The underlying norms and values identified suggest that the two countries share a similar value-base in relation This comparative study explores how breaches can be applied to unveil potential blindspots within the social constructs surrounding design practice in Sweden and New Zealand. When in-depth interviews with designers in both countries were analysed, similarities and differences appeared. The underlying norms and values identified suggest that the two countries share a similar value-base in relation

What is Wrong with Solidarity in EU Asylum and Migration Law?

In this article, we explore why solidarity has not worked according to expectation in EU migration and asylum law, and why it is unlikely to work in the future. First, we explore discourses of burden-sharing and solidarity in EU law from the 1990s up to the Lisbon treaty in 2009 to identify emergent path dependencies. This period saw the introduction of primary law provisions on solidarity, such a

Hypothalamic expression of huntingtin causes distinct metabolic changes in Huntington's disease mice

OBJECTIVE: In Huntington's disease (HD), the disease-causing huntingtin (HTT) protein is ubiquitously expressed and causes both central and peripheral pathology. In clinical HD, a higher body mass index has been associated with slower disease progression, indicating that metabolic changes may be involved in disease pathogenesis. Underlying mechanisms of metabolic changes in HD are not fully known,

Effects of excitotoxicity in the hypothalamus in transgenic mouse models of Huntington disease

Huntington disease (HD) is a fatal neurodegenerative movement disorder caused by an expanded CAG repeat in the huntingtin gene (HTT). The mutant huntingtin protein is ubiquitously expressed, but only certain brain regions are affected. The hypothalamus has emerged as an important area of pathology with selective loss of neurons expressing the neuropeptides orexin (hypocretin), oxytocin and vasopre

The Impact of the new EU Pact on Europe's External Borders: The Case of Greece

This book falls within the scope of the ASILE Project. ASILE studies the interactions between emerging international protection systems and the United Nations Global Compact for Refugees (UN GCR), with particular focus on the EU’s role. It examines the characteristics of international and country-specific asylum governance instruments and arrangements, and their compatibility with international an

Analyzing the Stressors for Frontline Soldiers Fighting Against Coronavirus Disease 2019 Pandemic

This study aimed to analyze stressors to which medical staff is vulnerable due to the coronavirus disease 2019 (COVID-19) pandemic. It also imposes a hierarchy on complex relations among stressors for excavating underlying structure and builds a model of interrelationships contrasting reality. The design of this study comprises a literature survey, data collection from primary sources, and analysi

The Perceived Demands of Ice Hockey Goaltending Movements on the Hip and Groin Region : An Elite Coach and Player Perspective

Background: Many ice hockey goaltending techniques force hip joints and groin muscles into extreme ranges of motion, which may increase the risk of hip and groin problems. Purpose: To explore how elite goaltenders and goaltending coaches perceive the demands of common goaltending techniques on the hip and groin region. We further explored differences in perception between goaltenders and their coa

(Un)weaving (Un)sustainability.

The spatio-temporal scale of design for sustainability has come full circle. What started within a technology-oriented global outlook, later evolving into a people-oriented and local view on change, now urges for a holistic, broad extent and multilevel design for sustainability. This paper enquires into the theories of social change that govern different approaches within the field, and positions

Leflunomide Inhibits rat-to-Mouse Cardiac Xenograft Rejection by Suppressing Adaptive Immune Cell Response and NF-κB Signaling Activation

Xenotransplantation is a potential solution for the severe shortage of human donor organs and tissues. The generation of humanized animal models attenuates strong innate immune responses, such as complement-mediated hyperacute rejection. However, acute vascular rejection and cell mediated rejection remain primary barriers to xenotransplantation, which limits its clinical application. In this study

Challenging the legality of externalisation in Oceania, Europe and South America: an impossible task?

The lack of success of legal challenges made against externalisation policies of various kinds is taken up in this article written by three authors focusing on three very different contexts: Oceania, Europe and South America. This comparative analysis highlights that externalisation practices are hard to challenge across the globe in the courts but for a variety of reasons. In Oceania, there is a

Transferable Skills Gained by Student Leaders in International SI-PASS Programs

Supplemental Instruction/Peer Assisted Study Sessions (SI-PASS) is a peer learning program used worldwide to improve students’ learning and performance in challenging courses in higher education. A bonus effect of the program is the transferable skills that the student leaders may develop when facilitating the study sessions. These student leaders can potentially gain communication, group manageme

Enhancing teachers’ classroom communication skills – Measuring the effect of a continued professional development programme for mainstream school teachers

Continued professional development (CPD), tailored to teachers’ needs and expectations, is required for updated skills and knowledge. In this study, twenty-five teachers working with first and second grade students participated in an 11-week programme focusing on enhancing classroom communication. The participating teachers were randomly assigned to either a direct intervention track (intervention

Impacts of Warming on Reciprocal Subsidies Between Aquatic and Terrestrial Ecosystems

Cross-ecosystem subsidies are important as their recipients often rely on them to supplement in situ resource availability. Global warming has the potential to alter the quality and quantity of these subsidies, but our knowledge of these effects is currently limited. Here, we quantified the biomass and diversity of the invertebrates exchanged between freshwater streams and terrestrial grasslands i

Assessing the effects of time interpolation of ndvi composites on phenology trend estimation

The accurate evaluation of shifts in vegetation phenology is essential for understanding of vegetation responses to climate change. Remote-sensing vegetation index (VI) products with multi-day scales have been widely used for phenology trend estimation. VI composites should be interpolated into a daily scale for extracting phenological metrics, which may not fully capture daily vegetation growth,