Despite the recent success of tyrosine kinase inhibitors (TKIs) in the treatment of chronic myeloid leukemia (CML), approximately 2-17% of patients develop clonal cytogenetic changes in the Philadelphia-negative (Ph(-)) cell population. A fraction of these patients, in particular those displaying trisomy 8 or monosomy 7, are at risk of developing a myelodysplastic syndrome (MDS) or acute myeloid l

Epithelial ovarian cancer (EOC) is the most lethal of all gynaecological malignancies and there is an urgent need to develop new prognostic and treatment predictive biomarkers for a more efficient therapy. The discovery of the RNA-binding motif protein 3 (RBM3) as a putative cancer biomarker was based on its differential expression in various cancer forms in the Human Protein Atlas (HPA). Further

Nekrolog över filmprofessorn, filmkritikern och filmteoretikern Robin Wood.

Intervju med David Cronenberg och Viggo Mortensen med anledning av biopremiären för filmen Eastern Promises.

This paper develops the foundations and the implications of the mechanisms proposed as possible triggers for the demographic transition and the process of socio-economic development. In particular it examines the role played by gender equality and its significance for the understanding of the development process which allowed economies to move out of a long period of stagnation into a state of sus

BACKGROUND: Hormone-sensitive lipase (HSL) is expressed predominantly in adipose tissue, where it plays an important role in catecholamine-stimulated hydrolysis of stored tri- and diglycerides, thus mobilizing fatty acids. HSL exhibits broad substrate specificity and besides acylglycerides it hydrolyzes cholesteryl esters, retinyl esters and lipoidal esters. Despite its role in fatty acid mobiliza

Popular Abstract in Swedish En burk målarfärg som har lämnats bortglömd, en senapsflaska som länge har stått upprätt i ett kylskåp eller ett nyinköpt filmjölkspaket som precis ska öppnas. Det finns många vardagliga situationer där vi stöter på separation av fasta partiklar från vätskan i så kallade suspensioner. Separationsprocessen kallas sedimentering och är den tillämpning som genomgående motivA consistent theme throughout this thesis is quasilinear partial differential equations (PDEs) appearing in one-dimensional models of sedimentation for solid-liquid separation of suspensions. We mainly focus on continuous sedimentation in so-called clarifier-thickeners (CTs), which are found in mineral processing and wastewater treatment. In addition to complications with shocks and non-unique sol