Objective: The goals of this study were to assess the associations of severe nonadherence to hydroxychloroquine (HCQ), objectively assessed by HCQ serum levels, and risks of systemic lupus erythematosus (SLE) flares, damage, and mortality rates over five years of follow-up. Methods: The Systemic Lupus International Collaborating Clinics (SLICC) Inception Cohort is an international multicenter init

Background. Patients on kidney replacement therapy (KRT) have been identified as a vulnerable group during the coronavirus disease 2019 (COVID-19) pandemic. This study reports the outcomes of COVID-19 in KRT patients in Sweden, a country where patients on KRT were prioritized early in the vaccination campaign. Methods. Patients on KRT between January 2019 and December 2021 in the Swedish Renal Reg

Aim: Necrotising enterocolitis (NEC) is the dominating surgical emergency in preterm neonates. The aims were to investigate indications, surgical management and mortality for surgically treated neonates with NEC. Methods: Data were retrieved from the Swedish Neonatal Quality Register for Swedish neonates with surgically treated NEC from 1 January 2017 to 31 December 2021. Diagnosis was validated b

For individuals with symptomatic wrist osteoarthritis (OA), pain is the central problem negatively affecting all aspects of life. Despite the recommendations that all OA patients should be offered self-management treatment options, this approach is often lacking for patients with wrist OA. In addition, there has been surprisingly little interest shown in investigating wrist OA patients' wishes and

Since the eruption of the war in Ukraine in February 2022, both Ukrainian and Russian diasporas in Sweden have been reframing themselves through memories, narratives and symbols. They have been revised in connection to the initial Russian-backed insurgency in eastern Ukraine and the annexation of Crimea (2014), the “homeland” as well as previous diasporic mobilizations in the country of residence.

Background: In the last decades different preclinical animal models of Parkinson's disease (PD) have been generated, aiming to mimic the progressive neuronal loss of midbrain dopaminergic (DA) cells as well as motor and non-motor impairment. Among all the available models, AAV-based models of human alpha-synuclein (h-aSYN) overexpression are promising tools for investigation of disease progression

One of the classical multi-view geometry problems is the so called P3P problem, where the absolute pose of a calibrated camera is determined from three 2D-to-3D correspondences. Since these solvers form a critical component of many vision systems (e.g. in localization and Structure-from-Motion), there have been significant effort in developing faster and more stable algorithms. While the current s

We present novel solutions to previously unsolved prob-lems of relative pose estimation from images whose calibration parameters, namely focal lengths and radial distortion, are unknown. Our approach enables metric reconstruction without modeling these parameters. The minimal case for reconstruction requires 13 points in 4 views for both the calibrated and uncalibrated cameras. We describe and imp

Finding the right coatings for cutting tools is essential in order to increase the tool wear resistance and, thus, to get better surface roughness for the machined workpieces, and to improve productivity. A coating requirements are not only its mechanical and strength properties, but also its response to a given load and a given wear exposure. To expand ideas about the phenomena and mechanisms of

By replacing conventional gray cast iron (GI) with compacted graphite iron (CGI), automotive industry could keep up with stricter regulations on emissions and demands on higher engine performance. CGI has improved properties as to GI but is more difficult to machine. This study evaluates sustainable machining performance during finish face milling when using minimum quantity lubrication applied ve

Objective Beta-blockers (BB) are an established treatment following myocardial infarction (MI). However, there is uncertainty as to whether BB beyond the first year of MI have a role in patients without heart failure or left ventricular systolic dysfunction (LVSD). Methods A nationwide cohort study was conducted including 43 618 patients with MI between 2005 and 2016 in the Swedish register for co

In this article, we trace a specific ‘situated bodily practice’, namely the ‘act of covering’ the head with a scarf during liturgy, in a church that has migrated from the Middle East to Sweden. This ‘veiled tradition’ is interpreted as a ‘ritual of migration’ that can cast light on the complexities of re-producing traditions in a new setting, functioning as a ‘cultural prism’ for the question of i

In the present topical mini-review, the beneficial impact of small-sided game football training for the increasing elderly global population is presented. As a multicomponent type of physical activity, football training executed on small pitched with 4–6 players in each team is targeting a myriad of physiological systems and causes positive adaptations of relevance for several non-communicable dis

Line segments are ubiquitous in our human-made world and are increasingly used in vision tasks. They are complementary to feature points thanks to their spatial extent and the structural information they provide. Traditional line detectors based on the image gradient are extremely fast and accurate, but lack robustness in noisy images and challenging conditions. Their learned counterparts are more

Cooperative behaviors among individuals of numerous species play a crucial role in social interactions. There is a special interest in investigating the occurrence of cooperation among apes because this knowledge could also shed light on evolutionary processes and help us understand the origin and development of cooperation in humans and primates in general. Gibbons are phylogenetically intermedia

INTRODUCTION: Variability in relationship of tau-based neurofibrillary tangles (T) and neurodegeneration (N) in Alzheimer's disease (AD) arises from non-specific nature of N, modulated by non-AD co-pathologies, age-related changes, and resilience factors. METHODS: We used regional T-N residual patterns to partition 184 patients within the Alzheimer's continuum into data-driven groups. These were c

High-energy synchrotron X-ray small-angle scattering (SAXS) is used to study the precipitate development during hot rolling and cooling of a commercial Ti–Nb micro-alloyed, high-strength, low-alloy (HSLA) steel. To study precipitation during hot rolling conditions, Gleeble and dilatometer trials are made. Samples are then studied at room temperature using SAXS in conjunction with transmission elec

Background: Lead exposure is associated with cardiovascular disease. Atherosclerosis has been hypothesized to be one of the underlying mechanisms behind this association. Aim: To investigate whether lead exposure is associated with an increased risk of atherosclerosis in the carotid arteries in a large Swedish population-based cohort. Methods: We performed a cross-sectional study using data from t