Peptides derived from apolipoprotein B (apoB)-100 have been previously used in vaccine preparations to treat atherosclerosis. Such vaccines have been shown to reduce atherosclerotic plaque development by 50 % in experimental animals, and this effect is associated with induction of T helper (Th)2 immune responses. In this study we immunised apolipoprotein E-deficient (apoE(-/-)) mice with apoB-100-

Miller R, D'Agostino D, Erlanson-Albertsson C, Lowe ME. Enterostatin deficiency increases serum cholesterol but does not influence growth and food intake in mice. Am J Physiol Endocrinol Metab 297: E856-E865, 2009. First published July 21, 2009; doi:10.1152/ajpendo.91008.2008.-A pentapeptide released from procolipase, enterostatin, selectively attenuates dietary fat intake when administered periph

A well-ordered surface oxide grown on Fe(110) has been studied using scanning tunneling microscopy (STM), low energy electron diffraction, low energy electron microscopy, and core level photoelectron spectroscopy. The iron oxide film exhibits wide terraces and is formed after exposure to 100-1000 L at 1 x 10(-6) mbar O-2 and 400 degrees C. Two domains, mirror symmetric in the Fe(110)-lattice mirro

Exposure of metazoan organisms to hypoxia engages a metabolic switch orchestrated by the hypoxia-inducible factor 1 (HIF-1). HIF-1 mediates induction of glycolysis and active repression of mitochondrial respiration that reduces oxygen consumption and inhibits the production of potentially harmful reactive oxygen species (ROS). Here, we show that FoxO3A is activated in hypoxia downstream of HIF-1 a

This article explores the “question of the animal” in Swedish artist Ann-Sofi Sidén’s project Queen of Mud, executed between 1988 and 2004. Queen of Mud revolves around a naked female creature, smeared from top to toe in wet mud, which interferes in human affairs and challenges thereby common assumptions about the human/animal divide and the human-animal continuum. By reading Queen of Mud over aga

Sture Bolin, professor of history at Lund University from 1938 to 1963, was, from the end of the 1940s, a good democrat. But he had earlier been of a very different mind. He did not want Swedish students to join the new International Confederation of Students, the CIE, because it was French-dominated and because German students were not involved. He liked Imperial Germany, but not the Weimar Repub

The author explores how a tobacco firm in crisis engaged in crisis communication and image repair work in a highly polarized ideological milieu. Through an analysis of the tobacco firm's public statements produced in the aftermath of a 1997 lawsuit, the author demonstrates how the firm dealt with its milieu by exploiting and embracing both of the ambient ideological poles. By embracing these poles

We present a dielectric continuum model that, at a semiquantitative level, explains why ion pair formation in water is favored by like-sized ions over unlike-sized pairs. Using both classical and ab initio continuum approaches, we show that the now well-established empirical rule, the so-called “law of matching water affinities”, can be rationalized in terms of ion solvation. Namely, pairing of di

Objective: A disturbed glucose metabolism has been observed in patients with aggressive behaviour. Interleukin (IL)-1β is a pro-inflammatory cytokine that can induce hypoglycaemia, but has also been suggested to be involved in the generation of hostility and aggression. Our group has previously shown an altered glucose metabolism in patients with self-inflicted aggressive behaviour. We investigat

Hot desert ecosystems are characterized by high soil temperatures with large fluctuations annually and diurnally. Thus, one could hypothesize that not only the microbial community would be adapted to high temperatures, but also have a large temperature range conducive for growth. We determined the temperature sensitivity of the soil bacterial community from the Chihuahuan Desert, Big Bend National

Xylan was extracted from wheat bran after heat pretreatment in water using either an autoclave or a microwave oven. Xylooligosaccharides (XOS) were produced from the xylan using the thermostable xylanase RmXyn10A and the potential prebiotic properties of XOS were studied in vitro with different human gut bacteria: Lactobacillus brevis (DSMZ 1269), Bifidobacterium adolescentis (ATCC 15703) and two

A fundamental precept of geochemistry is that arsenate coordinates at mineral surfaces in a predominately bridging-bidentate fashion. We show that this is incorrect for the model system, arsenate adsorbed at the surface of goethite (alpha-FeOOH), using a combination of XRD, EXAFS, and IR spectroscopic results. We report the crystal structure of pentaamminecobalt(III) arsenate, which consists of mo

A cornerstone in the successful application of semiconductor nanowire devices is controlled impurity doping. In this review article, we discuss the key results in the field of semiconductor nanowire doping. Considerable development has recently taken place in this field, and half of the references in this review are less than 3 years old. We present a simple model for dopant incorporation during i

We have studied the nocturnal flight behaviour of the common swift (Apus apus L.), by the use of a tracking radar. Birds were tracked from Lund University in southern Sweden during spring migration, summer roosting flights and autumn migration. Flight speeds were compared with predictions from flight mechanical and optimal migration theories. During spring, flight speeds were predicted to be highe

Cholestasis is a frequent clinical syndrome, which is caused by a dysfunction in bile formation of the hepatocyte or from obstruction of the biliary tract. This is associated with inflammation of the liver tissue, resulting in severe liver injury. In this inflammatory process, leukocyte recruitment has emerged as a key feature. Therefore, the aim of this thesis was to analyze the detailed mechanis

This text deals with a problem concerning processes of the productive power of knowledge. We draw on so called poststructural theories challenging the classical image of thought – as hinged upon a representational logic identifying entities in a rigid sense – when formulating a problem concerning the gap between knowledge and the object of knowledge. More specifically we are looking at this proble

Background: Dental caries is unevenly distributed within populations with a higher burden in low socio-economy groups. Several attempts have been made to allocate resources to those that need them the most; there is a need for convenient approaches to population-based monitoring of caries risk over time. The aim of this study was to develop the geo-map concept, addressing time trends in caries ris