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LETM proteins play a role in the accumulation of mitochondrially encoded proteins in Arabidopsis thaliana and AtLETM2 displays parent of origin effects

The Arabidopsis thaliana genome contains two genes with homology to the mitochondrial protein LETM1 (leucine zipper-EF-hand-containing transmembrane protein). Inactivation of both genes, Atletm1 and Atletm2, together is lethal. Plants that are hemizygous for AtLETM2 and homozygous for Atletm1 (letm1(-/-) LETM2(+/-)) displayed a mild retarded growth phenotype during early seedling growth. It was sh

TCP transcription factors link the regulation of genes encoding mitochondrial proteins with the circadian clock in Arabidopsis thaliana

Diurnal regulation of transcripts encoding proteins located in mitochondria, plastids, and peroxisomes is important for adaptation of organelle biogenesis and metabolism to meet cellular requirements. We show this regulation is related to diurnal changes in promoter activities and the presence of specific cis-acting regulatory elements in the proximal promoter region [TGGGC(C/T)], previously defin

Det grälsjuka samtalet skadar demokratin

Både medborgare och politiker är trötta på trätandet i dagens politiska debatt. Samtalet måste präglas mer av dialog - annars växer politikerföraktet liksom de populistiska strömningarna. Ytterst riskeras demokratin.

Separating Blood and Water: Perfusion and Free Water Elimination from Diffusion MRI in the Human Brain.

The assessment of the free water fraction in the brain provides important information about extracellular processes such as atrophy and neuroinflammation in various clinical conditions as well as in normal development and aging. Free water estimates from diffusion MRI are assumed to account for freely diffusing water molecules in the extracellular space, but may be biased by other pools of molecul

Low diversity and high intra-island variation in prevalence of avian Haemoproteus parasites on Barbados, Lesser Antilles

Common bird species were screened during May and June 2007 on Barbados for haemosporidian parasites (Haemosporida) of the genera Haemoproteus and Plasmodium to determine whether the low parasite diversity reported in previous studies might have reflected limited sampling. PCR screening and DNA sequencing revealed a single predominant lineage of Haemoproteus identified as H. coatneyi. Sixty-two out

Efficient Software Implementation of Stream Programs

The way we use computers and mobile phones today requires large amounts of processing of data streams. Examples include digital signal processing for wireless transmission, audio and video coding for recording and watching videos, and noise reduction for the phone calls. These tasks can be performed by stream programs—computer programs that process streams of data. Stream programs can be composed

Science facilitets and stakeholder management : How a pan-European research facility ended up in a small Swedish University town

This is the story of how a large research facility of broad European and global interest, the European Spallation Source (ESS), ended up in the small university town of Lund in Sweden. This happened in spite of the fact that a number of influential European countries were at one time or another competitors to host the facility. It is also a story about politics which attempts to illustrate how clo

Association between TLR9 rs5743836 polymorphism and risk of recurrent venous thromboembolism

Recent gene knockout studies on mice have shown the role of toll-like receptor 9 (TLR9) in resolution of venous thromboembolism (VTE) through sterile inflammation. However, the role of a putative functional TLR9 polymorphism (rs5743836) in risk assessment of VTE recurrence remains unknown. The aim of our study was to investigate the TLR9 rs5743836 polymorphism in VTE patients and its association w

Active Fault Isolation: A Duality-Based Approach via Convex Programming

This paper presents the mathematical conditions and the associated design methodology of an active fault diagnosis technique for continuous-time linear systems. Given a set of faults known a priori, the system is modeled by a finite family of linear time-invariant systems, accounting for one healthy and several faulty configurations. By assuming bounded disturbances and using a residual generator,

Making a market for alternatives: marketing devices and the qualification of a vegan milk substitute

The aim of this paper is to describe, conceptualise and critically discuss how and with what consequences marketing is used to construct a mass market for vegan substitutes. Drawing on the concepts of the marketing device and qualification, it shows how Oatly – a Swedish company making oat-based products – enrols three sets of marketing devices, i.e. digital media, packaging and stores, to simulta

Microsporidia in a woodland pool I. Lanatospora costata sp. n. (opisthosporidia, microsporidia), parasite of megacyclops viridis (Crustacea, Copepoda) : Fine structure and molecular phylogeny

Lanatospora costata sp. n., a new microsporidian parasite of the adipose and connective tissue cells of Megacyclops viridis (Jurine, 1820) (Copepoda: Cyclopidae) is described. It was isolated from a woodland pool with a rich and diverse fauna of microsporidiainfected small crustaceans and insect larvae. The parasite is structurally similar to the genus Lanatospora Voronin, 1989, characterized by a

Film cooling effects on the tip flow characteristics of a gas turbine blade

An experimental investigation of the tip flow characteristics between a gas turbine blade tip and the shroud was conducted by a pressure-test system and a particle image velocimetry (PIV) system. A three-times scaled profile of the GE-E3 blade with five film cooling holes was used as specimen. The effects on flow characteristics by the rim width and the groove depth of the squealer tip were reveal

Effects of the mainstream turbulence intensity and slot injection angle on the endwall cooling and phantom cooling of the vane suction side surface

In order to obtain better performance, gas turbines always operate with high inlet temperature. This contributes to a high level of thermal load on the first stage vane endwall. To ensure safe operation of a gas turbine within a proper temperature range, the cooling performance of the vane endwall must be further investigated. In the present study, effects of the mainstream turbulence and upstream

The transition of energy intensive processing industries towards Deep decarbonization: Characteristics and implications for future research

Energy-intensive processing industries (EPIs) produce iron and steel, aluminum, chemicals, cement, glass, and paper and pulp and are responsible for a large share of global greenhouse gas emissions. To meet 2050 emission targets, an accelerated transition towards deep decarbonization is required in these industries. Insights from sociotechnical and innovation systems perspectives are needed to bet