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Giant molecular clouds (GMCs) are believed to affect the biospheres of planets as their host star passes through them. We simulate the trajectories of stars and GMCs in the Galaxy and determine how often stars pass through GMCs. We find a strong decreasing dependence with Galactocentric radius, and with the velocity perpendicular to the Galactic plane, Vz. The XY-component of the kinematic heating
Background: There is a worldwide development toward using data from hospital-based stroke registers to estimate epidemiological trends. However, incomplete case ascertainment may cause selection bias. We examined the completeness of case ascertainment and selection bias in two hospital-based Swedish stroke registers. Methods: First-ever stroke cases between March 2015 and February 2016 in the catc
Nature-based solutions (NBS) is the latest contribution to the green concept family. NBS is defined as actions based in nature addressing societal challenges. In this study, we lean on the concept boundary object, broken down into three analytical categories: use, core ideas and granularities, to explore the cohesive and fragmenting powers of the NBS concept, and discuss its future role in green s
To circumvent the detrimental effects of large-volume injection with fixed-loop injector in modern supercritical fluid chromatography, the feasibility of performing multiple injection was investigated. By accumulating analytes from a certain number of continual small-volume injections, compounds can be concentrated on the column head, and this leads to signal enhancement compared with a single inj
Scar formation after injury of the brain or spinal cord is a common event. While glial scar formation by astrocytes has been extensively studied, much less is known about the fibrotic scar, in particular after stroke. Platelet-derived growth factor receptor ß-expressing (PDGFRß+) pericytes have been suggested as a source of the fibrotic scar depositing fibrous extracellular matrix (ECM) proteins a
Philosophers’ search for the best way to explain human actions has led many to accept a core psychological model that can be supplemented by other forms of action explanation when needed. Rather than settling for this model – where everything ultimately hinges on psychological explanation – this paper argues for a pluralistic view. It does not claim that the psychological view is wrong, only that Philosophers’ search for the best way to explain human actions has led many to accept a core psychological model that can be supplemented by other forms of action explanation when needed. Rather than settling for this model –where everything ultimately hinges on psychologicalexplanation – this paper argues for a pluralistic view. It does not claim that the psychological view is wrong, only that it
In this work, we discuss a classification of (,Î)-Freudenthal-Kantor triple systems defined by bilinear forms and give all examples of such triple systems. From these results, we may see a construction of some simple Lie algebras or superalgebras associated with their Freudenthal-Kantor triple systems. We also show that we can associate a complex structure into these (,Î)-Freudenthal-Kantor triple
The report draws on socio-legal theory in relation to growing concerns over fairness, accountability and transparency of societally applied artificial intelligence (AI) and machine learning. The purpose is to contribute to a broad socio-legal orientation by describing legal and normative challenges posed by applied AI. To do so, the article first analyses a set of problematic cases, e.g. image rec
Molecular changes occurring during invasion and clinical progression of cancer are difficult to study longitudinally in patient-derived material. A unique feature of urothelial bladder cancer (UBC) is that patients frequently develop multiple nonmuscle invasive tumors, some of which may eventually progress to invade the muscle of the bladder wall. Here, we use a cohort of 73 patients that experien
This article focuses on the complex relationship between development and disaster risk. Development and disaster risk are closely linked as the people and assets exposed to risk, as well as their vulnerability and capacity, are largely determined by development processes. Transformation is key to moving from current development patterns that increase, create or unfairly distribute risks, to forms
To develop and apply goals for future sustainability, we must consider what people care about and what motivates them to engage in solving sustainability issues. Sense of place theory and methods provide a rich source of insights that, like the social-ecological systems perspective, assume an interconnected social and biophysical reality. However, these fields of research are only recently beginni
Monoclonal antibodies targeting CD20 are central in the treatment of B-cell lymphomas. In diffuse large B-cell lymphoma (DLBCL), inactivating mutations of the histone acetyltransferases CREB-binding protein (CBP) and EP300 are common. Moreover, knockdown of CBP in DLBCL has been shown to result in aberrant transcriptional silencing. Expression of CD20 is sensitive to epigenetic manipulation, and h
Objective: Posterior circulation ischemic stroke (PCiS) constitutes 20–30% of ischemic stroke cases. Detailed information about differences between PCiS and anterior circulation ischemic stroke (ACiS) remains scarce. Such information might guide clinical decision making and prevention strategies. We studied risk factors and ischemic stroke subtypes in PCiS vs. ACiS and lesion location on magnetic
The content of obsessions in obsessive–compulsive disorder (OCD) often run contrary to the actual self of the individual experiencing them. The ego-dystonic nature of obsessions has led some researchers to propose that individuals with OCD form these false beliefs about themselves due to limited introspective access. The current study therefore aimed to extend on recent findings from non-clinical
The ecology and biogeochemistry of lakes in the subarctic region are particularly sensitive to changes in the abundance and optical properties of dissolved organic matter (DOM). External input of colored DOM to these lakes is an extensively researched topic, but little is known about potential reciprocal feedbacks between the optical properties of DOM and internal microbial processes in the water.
