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Lazarillo, a glycoprotein involved in axon growth and guidance in the grasshopper embryo, is the only member of the lipocalin family that is attached to the cell surface by a GPI anchor. Recently, the study of Lazarillo homologous genes in Drosophila and mouse has revealed new functions in the regulation of lifespan, stress resistance and neurodegeneration. Here we report an analysis of biochemica
The current interest in organizational culture, identity, image and reputation and in organizational discourse points towards the pressure on contemporary organizations to focus attention on the symbolic dimensions of their activities. The phenomenon of branding, while originally portrayed as a marketing tool, can also be understood as an exercise in management of meaning. Branding does not only i
We evaluated midterm functional outcome after endovascular occlusion of aneurysms in patients with subarachnoid haemorrhage (SAH) and determined the incidence of late rebleeding as an additional prognostic parameter. We treated 79 consecutive patients with SAH from an intracranial aneurysm admitted from a neurological intensive care unit by the endovascular route between 1993 and 1997 and 52 survi
The paravermal cerebellar cortex contains three spatially separate zones (the C1, C3 and Y zones) which form a functionally coupled system involved in the control of voluntary limb movements. A series of 'modules' has been postulated, each defined by a set of olivary neurons with similar receptive fields, the cortical microzones innervated by these neurons and the group of deep cerebellar nuclear
During the remodeling phase of fracture healing in mice, the callus gradually transforms into a double cortex, which thereafter merges into one cortex. In large animals, a double cortex normally does not form. We investigated whether these patterns of remodeling of the fracture callus in mice can be explained by mechanical loading. Morphologies of fractures after 21, 28, and 42 days of healing wer
The recipe described gives an easy to prepare, easy to handle and inexpensive fat phantom for the determination of absorbed-power distributions of microwave/radiofrequency radiation. If the phantom is used together with the high-water-content phantom (Guy 1971) the absorbed-power distributions can be determined in structured tissues. The phantom has been used in Utrecht to test the e-m boundary co
Pure red cell aplasia (PRCA) is a rare, but important, complication of erythropoietin (EPO) replacement therapy in patients with renal disease. There is no consensus about the best way to treat this condition; however, recent reports indicated that immunosuppressive therapy is beneficial. We report a patient with EPO-induced PRCA treated with a regimen initially designed for antifactor VIII antibo
Isozyme markers and morphological characters were studied in four populations of Sphagnum capillifolium and S. quinquefarium. Recombinant plants were found in three populations, where the two species occur sympatrically. All recombinants possessed different haplotypes and combinations of morphological characters, which show that they are results of independent hybridization events. Strongly male-b
We propose a traffic model based on microscopic stochastic dynamics. We built a Markov chain equipped with an Arrhenius interaction law. The resulting stochastic process is comprised of both spin-flip and spin-exchange dynamics which models vehicles exiting, entering and interacting in a two-dimensional lattice environment corresponding to a multi-lane highway. The process is further equipped with
Many explanations have been provided for variations of the spatial distribution and thickness of till sheets. This paper gives new insight into the architecture of a stratigraphically distinct till sheet as a function of the type of substratum and preadvance topography at a scale of similar to 10 km. This emphasises the sensitivity of the subglacial system to changes in the basal drainage conditio
Conventional Optically Stimulated Luminescence (OSL) dating using the equivalent dose distributions of 8 mm aliquots have been extended to key stratigraphical sites in southernmost Sweden and the island of Bornholm. The objective has been to bridge the lack of an independent chronology, which might catalyze a new understanding of the ice flow patterns related to the initiation of the Last Glacial
Since the late 1970s the central government of China has initiated several ecological environmental protection projects. The most significant of these has been the tui geng huan lin (returning cultivated land to forest and pasture) project in operation since the late 1990s. China's northwest region is characterized by lack of water resources, yet such resources are of vital importance. There is sc
A tissue proteomics process is presented where hepatocyte cell isolation in combination with two-dimensional (2-D) gel electrophoresis and mass spectrometric identification were used to annotate the liver proteome. Laser microdissection of 8 m liver tissue sections was performed and protein expression profiling was compared using a variety of quantities of input cells, and gel separation condition
In this paper ethical implications of parental participation in paediatric care are discussed. The paper is based on interviews with 20 parents, whose children were admitted and operated on at a paediatric surgery department in Sweden. In one part of the interview the parent was invited to speak about situations experienced as problematic during the hospitalization. Three different types of situat
BACKGROUND: Occlusion of the superior mesenteric artery (SMA) demands prompt recognition and diagnosis. No accurate diagnostic method is available. The aim of this study was to determine whether the fibrinolytic marker D-dimer is a useful early marker of acute bowel ischaemia. METHODS: Fourteen patients suspected of having acute bowel ischaemia were analysed for an increase in plasma D-dimer level
Since emf measurements with amalgam electrodes have been used, in most studies of the stabilities of complexes between soft metal acceptors and halide ions a series of investigations of the kinetics of electrode reactions were accomplished with halide systems of metal ions in the Groups 11 and 12 in aqueous and/or DMSO solutions. The aim was to establish which complexes contribute to the exchange
We characterize and control the harmonic emission in the spectral and spatial domains in order to define in which conditions the harmonic radiation can be a high-quality seed for soft x-ray and x-ray free-electron lasers. The length of the gas cell, where harmonics are generated, was optimized and the energy per pulse was determined in absolute value with a calibrated x-ray photodiode. The beam sp
