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The crystal structure of seleno-glutathione peroxidase from human plasma at 2.9 Å resolution
Metabolic control of BRISC–SHMT2 assembly regulates immune signalling
Serine hydroxymethyltransferase 2 (SHMT2) regulates one-carbon transfer reactions that are essential for amino acid and nucleotide metabolism, and uses pyridoxal-5′-phosphate (PLP) as a cofactor. Apo SHMT2 exists as a dimer with unknown functions, whereas PLP binding stabilizes the active tetrameric state. SHMT2 also promotes inflammatory cytokine signalling by interacting with the deubiquitylatin
Regulation of phospholipid biosynthesis in isolated rat hepatocytes. Effect of different substrates
RIFM fragrance ingredient safety assessment, cyclopentanol, 2-(2-hexen-1-yl)-, CAS Registry Number 34686-67-4
RIFM fragrance ingredient safety assessment, coumarin, CAS Registry Number 91-64-5
Severe asthma: Entering an era of new concepts and emerging therapies: Highlights of the 4th international severe asthma forum, Madrid, 2018
The thioredoxin and glutaredoxin systems are efficient electron donors to human plasma glutathione peroxidase
Human plasma glutathione peroxidase (GSH-Px) is a distinct extracellular selenoenzyme that detoxifies hydroperoxides when used with GSH in high (mM) non-physiological concentrations. We have discovered that NADPH and human thioredoxin reductase (TR) by itself or with thioredoxin (Trx) are efficient electron donors to this human plasma peroxidase. Incubation of 0.05 microM TR with 0.25 microM GSH-P
Torsten Ekman, Helsingfors röda fanor, anm. Roger Johansson
Formeringen av den tidiga finska arbetarrörelsen med fokus på Helsingfors
Fackförbundens sjukkassebildande : En studie i facklig självhjälp 1886-1910
Sex differences in helping effort reveal the effect of future reproduction on cooperative behaviour in birds
The evolution of helping behaviour in species that breed cooperatively in family groups is typically attributed to kin selection alone. However, in many species, helpers go on to inherit breeding positions in their natal groups, but the extent to which this contributes to selection for helping is unclear as the future reproductive success of helpers is often unknown. To quantify the role of future
Composition of rat liver triacylglycerols and diacylglycerols
Farliga fantasier i Smålandsposten
Diskussion om händelserna i Ådalen 1931
Peroxidative changes in brain cortical fatty acids and phospholipids, as characterized during Fe2+- and ascorbic acid-stimulated lipid peroxidation in vitro
MAROKKO : BLOG- TIL-TEATER
One Gene, Several Diseases : The Characteristics of Pleiotropic Proteins
Paradise : En videoinstallation med kaffe og omsorg
Automated Bone Scan Index as an Imaging Biomarker to Predict Overall Survival in the Zometa European Study/SPCG11
BACKGROUND: Owing to the large variation in treatment response among patients with high-risk prostate cancer, it would be of value to use objective tools to monitor the status of bone metastases during clinical trials. Automated Bone Scan Index (aBSI) based on artificial intelligence has been proposed as an imaging biomarker for the quantification of skeletal metastases from bone scintigraphy.OBJE
Functional and Oncologic Outcomes Between Open and Robotic Radical Prostatectomy at 24-month Follow-up in the Swedish LAPPRO Trial
BACKGROUND: The adoption of robot-assisted laparoscopic radical prostatectomy (RALP) has increased rapidly, despite lack of conclusive evidence of its superiority regarding long-term outcomes over open retropubic RP (RRP). In 2015, we reported on 12-mo follow-up from the LAPPRO trial showing a moderate advantage of RALP regarding erectile dysfunction. No significant differences were seen for urina
Apalutamide for Metastatic, Castration-Sensitive Prostate Cancer
BACKGROUND: Apalutamide is an inhibitor of the ligand-binding domain of the androgen receptor. Whether the addition of apalutamide to androgen-deprivation therapy (ADT) would prolong radiographic progression-free survival and overall survival as compared with placebo plus ADT among patients with metastatic, castration-sensitive prostate cancer has not been determined.METHODS: In this double-blind,