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Blood lipids in 75,048 type 2 diabetic patients: a population-based survey from the Swedish National diabetes register

Background: Type 2 diabetes and diabetic dyslipidemia are high-risk conditions for cardiovascular disease. However, the description of the distribution of blood lipids in diabetic patients has not been based on population-based surveys. The aim of this study was to describe diabetic dyslipidemia in a large unselected sample of patients from the Swedish National Diabetes Register. Methods: Blood li

Desirable Skills? Non-Nordic citizens applying for work permits in Sweden, 1947–1950

Sweden’s rapid economic growth after World War II meant that the native labour supply was incapable of meeting the high demand, especially for industrial labourers. Three agreements on organised collective transfers were signed, but a large majority of the labour migrants came on their own initiative. Not all applicants were equally welcomed. In this article, logistic regressions are used to inves

Coreless vortices in rotating two-component quantum droplets

The rotation of a quantum liquid induces vortices to carry angular momentum. When the system is composed of multiple components that are distinguishable from each other, vortex cores in one component may be filled by particles of the other component, and coreless vortices form. Based on evidence from computational methods, here we show that the formation of coreless vortices occurs very similarly

Dispersionless Spin Waves and Underlying Field-Induced Magnetic Order in Gadolinium Gallium Garnet.

We report the results of neutron diffraction and inelastic neutron scattering on a powder sample of Gd_{3}Ga_{5}O_{12} at high magnetic fields. Analysis of the diffraction data shows that in high fields (B≳1.8 T) the spins are not fully aligned, but are canted slightly as a result of the dipolar interaction. The magnetic phase for fields ≲1.8 T is characterized by antiferromagnetic peaks at (210)

Fibre intake and incident colorectal cancer depending on fibre source, sex, tumour location and Tumour, Node, Metastasis stage.

Studies on fibre intake and incident colorectal cancer (CRC) indicate inverse associations. Differences by tumour stage have not been examined. We examined associations between fibre intake and its sources, and incidental CRC. Separate analyses were carried out on the basis of sex, tumour location and the Tumour, Node, Metastasis (TNM) classification. The Malmö Diet and Cancer Study is a populatio

Age- and Sex-Specific Causal Effects of Adiposity on Cardiovascular Risk Factors.

Observational studies have reported different effects of adiposity on cardiovascular risk factors across age and sex. Since cardiovascular risk factors are enriched in obese individuals, it has not been easy to dissect the effects of adiposity from those of other risk factors. We used a Mendelian randomization approach, applying a set of 32 genetic markers to estimate the causal effect of adiposit

RapidArc treatment verification in 3D using polymer gel dosimetry and Monte Carlo simulation.

The aim of this study was to verify the advanced inhomogeneous dose distribution produced by a volumetric arc therapy technique (RapidArc) using 3D gel measurements and Monte Carlo (MC) simulations. The TPS (treatment planning system)-calculated dose distribution was compared with gel measurements and MC simulations, thus investigating any discrepancy between the planned dose delivery and the actu

Platelet Monoamine Oxidase B Activity Did Not Predict Destructive Personality Traits or Violent Recidivism: A Prospective Study in Male Forensic Psychiatric Examinees.

Aims: This prospective study was designed to replicate previous findings of an association between the platelet monoamine oxidase B (MAO-B) activity and factors of relevance for criminal behaviour in a well-documented clinical study population. Methods: Subjects (n = 77, aged 17-76 years, median 30 years) were recruited among consecutive perpetrators of severe interpersonal violent and/or sexual c

Tumor selectivity at short times following systemic administration of a liposomal temoporfin formulation in a murine tumor model

Meso-tetra(hydroxyphenyl)chlorin (mTHPC) (INN: Temoporfin) is one of the most potent photodynamically active substances in clinical use. Treatment protocols for Temoporfin-mediated photodynamic therapy often rely on drug-light intervals of several days in order for the photosensitizer to accumulate within the target tissue, though tumor selectivity is limited. Here, the mTHPC localization was stud

V-ATPase-mediated phagosomal acidification is impaired by Streptococcus pyogenes through Mga-regulated surface proteins.

Streptococcus pyogenes, a significant bacterial pathogen in humans, interferes with the membrane traffic of human neutrophils and survives following phagocytosis. The mechanism(s) behind this property is not known, but in contrast to wild-type bacteria, mutant bacteria lacking virulence factors regulated by the transcriptional regulator Mga, are phagocytosed and killed. In the present work we inve

Feedback interstitial diode laser (805 nm) thermotherapy system: Ex vivo evaluation and mathematical modeling with one and four-fibers

Background and Objective: In this study a newly developed microprocessor controlled power regulation and thermometry system integrated with a diode laser (805 nm wavelength) was evaluated with respect to temperature distribution, effectiveness of regulation, and ability to predict temperature distributions by computer simulation. Study Design/Materials and Methods: Experiments were performed in gr

Quantification of N2O emission pathways via a 15N tracing model

A 15N tracing model was developed to analyse nitrous oxide (N2O) dynamics in terrestrial ecosystems, which build on previous tracing models for the quantification of the main mineral nitrogen (N) transformations and soil nitrite (NO2 -) dynamics. The N2O dynamics in the model are directly associated with three NO2 - sub-pools. Four pathways for N2O production in soil were considered in the model: