Background: Relapse of hepatitis C virus (HCV) infection after liver transplantation (LT) is universal. Tolerance for treatment with pegylated-interferon (peg-IFN) and ribavirin (RBV) is suboptimal and withdrawals due to adverse events frequent. We sought to improve tolerance for treatment to improve outcome. Methods: We used concentration-guided RBV dosing to achieve an intended 10 mu mol/L conce

Popular Abstract in Swedish Prostatacancer är idag den vanligast diagnostiserade cancerformen i Sverige. De flesta nya fallen som upptäcks är lokaliserade till prostatan och kan i hög utsträckning botas med antingen operation eller strålbehandling. För en del män har dock prostatacancern hunnit sprida sig redan vid diagnos och då är chansen till bot mycket liten. Vid utbredd spridning, så kallad mProstate cancer is one of the most common malignancies. Its treatment is highly dependent on the presence or absence of metastases. The available invasive and non-invasive modalities for detecting metastases are imperfect. Positron-emission tomography fused with computed tomography (PET/CT) is a non-invasive method for detecting metastases that is presently evaluated for prostate cancer. Fluoride

En analys av kvinnors myndighetsansökningar i Sverige under 1800-talet.

The association of Helicobacter pylori with gastroduodenal diseases is well established. The mode of transmission of the organism is still unclear, although the faecal-oral route has been proposed. H. pylori has been detected in gastric antrum, dental plaques, faeces and water. In the light of these studies we attempted to detect H. pylori in antral biopsies, dental plaques, and stool specimens of

Hypoxia, a growing worldwide problem, has been intermittently present in the modern Baltic Sea since its formation ca. 8000 cal. yr BP. However, both the spatial extent and intensity of hypoxia have increased with anthropogenic eutrophication due to nutrient inputs. Physical processes, which control stratification and the renewal of oxygen in bottom waters, are important constraints on the formati

Purpose - The purpose of this paper is to examine if gendered differences in risk perception automatically mean that women and men rank the hazards of their community differently, focusing any risk reduction measures on the priority risks of only part of the population. Design/methodology/approach - The study applies survey research through structured personal interviews in three municipalities in

There is an urgent need for biomarkers to enable early diagnosis of Alzheimer's disease (AD). It has recently been shown that a variant within the clusterin gene is associated with increased risk of AD and plasma levels of clusterin have been found to be associated with the risk of AD. We, therefore, investigated the diagnostic value of clusterin by quantifying clusterin using an ELISA in plasma f

Cnidarians are often used as model animals in studies of eye and photopigment evolution. Most cnidarians display photosensitivity at some point in their life-cycle ranging from extraocular photoreception to image formation in camera-type eyes. The available information strongly suggests that some cnidarians even possess multiple photosystems. The evidence is strongest within Cubomedusae where all

The number of applications sharing the same embedded device is increasing dramatically. Very efficient mechanisms (resource managers) for assigning the CPU time to all demanding applications are needed. Unfortunately, existing optimization-based resource managers consume too much resource themselves. In this paper, we address the problem of distributed convergence to fair allocation of CPU resourc

Popular Abstract in Swedish Under 1700- och 1800-talet omvandlades det svenska jordbruket som en del av en euro¬peisk utveckling som uppvisar övergripande likheter. De genomgripande förändringarna och deras betydelse för den långsiktiga samhällsutvecklingen motiverar att man talar om en agrar revolution. Trots övergripande likheter rymde emellertid den agrara revolutionen såväl regio-nala som lokaThe great transformation of Swedish agriculture in the 18th and 19th centuries was part of a European-wide development sharing similar characteristics. While researchers agree that extensive agro-technological, social and institutional changes took place, opinions differ with regards to the causes, spread, timing and sequence of events. Through a systematic study of agricultural production, land u

Popular Abstract in Swedish I Immi Lundins avhandling Att föra det egna till torgs står 1960-, 1970- och 1980-talen i fokus. Tre kvinnliga författares debutromaner, en från varje decennium, undersöks och sätts i relation till de förändrade positionerna i den offentliga kvinno- och litteraturdebatten under trettioårsperioden. Frågan som avhandlingen söker svar på gäller romanernas samspel med tillkThe Swedish debate both on the role of literature and on the social position of women underwent rapid change during the thirty years from 1960 to 1990. In Bringing the Personal to Market: Narrative, Subject-Matter and Contemporary History in the First Novels of Kerstin Strandberg, Enel Melberg and Eva Adolfsson, the debut novels of three female authors’ are close-read from a thematic and narratolo

The valence of the europium dopant and selected rare earth co-dopants (Ce3+, Dy3+, and Yb3+) in the Sr2MgSi2O7:Eu2+,R3+ persistent luminescence materials were studied by room temperature XANES measurements. The results indicated the co-existence of both divalent and trivalent europium in all the studied materials. The relative amount of Eu3+ was observed to increase upon increasing exposure to X-r

The serum PSA test still is the most important biomarker for the detection and follow-up of prostate cancer. PSA-based screening can reduce disease specific mortality but coinciding unnecessary testing and overdiagnosis warrant further research for more specific biomarkers. Numerous studies of both serum and urine-based prostate cancer biomarker candidates have been presented the last ten years. H

Single-shaft gas turbines are sensitive to frequency changes which might affect the grid stability during large frequency drops. This paper presents a new control system that uses steam injection as an auxiliary input to improve the transient performance of the gas turbine during frequency drops. Steam injection is beneficial because it reduces the peak temperature in the combustion chamber and au

The need for reliable measurement of droplet velocities and droplet size has increased with the more widespread use of water mist systems. Two optical measuring techniques have been investigated, Particle Image Velocimetry (PIV) and phase Doppler anemometry (PDA). Measurements have been performed on two high-pressure nozzles, a hollow cone nozzle and a full cone nozzle. Both methods performed well

Poisson's ratio of an isotropic and free elastic plate is estimated from the polarization of the first symmetric acoustic zero-group velocity Lamb mode. This polarization is interpreted as the ratio of the absolute amplitudes of the surface normal and surface in-plane components of the acoustic mode. Results from the evaluation of simulated datasets indicate that the presented relation, which link

Soft X-ray induced chemistry of H2O, CO and CH3OH and the effects of the water and nitric acid hydrate (HNO3 center dot 1.65H(2)O) matrix on the photochemistry of CO and CH3OH have been investigated using NEXAFS spectroscopy. For pure H2O, CO and CH3OH ices, we show that the destruction rates are strongly limited by back reactions, leading to strikingly high survival rates of these molecules upon